Orientia tsutsugamushi Ank5 promotes NLRC5 cytoplasmic retention and degradation to inhibit MHC class I expression.

Autor: Adcox HE; Department of Microbiology and Immunology, Virginia Commonwealth University Medical Center, School of Medicine, Richmond, VA, USA.; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, School of Medicine, Charlottesville, VA, USA., Hunt JR; Department of Microbiology and Immunology, Virginia Commonwealth University Medical Center, School of Medicine, Richmond, VA, USA., Allen PE; Department of Microbiology and Immunology, Virginia Commonwealth University Medical Center, School of Medicine, Richmond, VA, USA., Siff TE; Department of Microbiology and Immunology, Virginia Commonwealth University Medical Center, School of Medicine, Richmond, VA, USA., Rodino KG; Department of Microbiology and Immunology, Virginia Commonwealth University Medical Center, School of Medicine, Richmond, VA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Ottens AK; Department of Anatomy and Neurobiology, Virginia Commonwealth University Medical Center, School of Medicine, Richmond, VA, USA., Carlyon JA; Department of Microbiology and Immunology, Virginia Commonwealth University Medical Center, School of Medicine, Richmond, VA, USA. jason.carlyon@vcuhealth.org.

Publikováno v: Nature communications [Nat Commun] 2024 Sep 14; Vol. 15 (1), pp. 8069. Date of Electronic Publication: 2024 Sep 14.

Aging influence on pulmonary and systemic inflammation and neural metabolomics arising from pulmonary multi-walled carbon nanotube exposure in apolipoprotein E-deficient and C57BL/6 female mice.

Autor: Young TL; Department of Pharmaceutical Sciences, University of New Mexico, Albuquerque, NM, USA., Scieszka D; Department of Pharmaceutical Sciences, University of New Mexico, Albuquerque, NM, USA., Begay JG; Department of Pharmaceutical Sciences, University of New Mexico, Albuquerque, NM, USA., Lucas SN; Department of Pharmaceutical Sciences, University of New Mexico, Albuquerque, NM, USA., Herbert G; Department of Pharmaceutical Sciences, University of New Mexico, Albuquerque, NM, USA., Zychowski K; College of Nursing, University of New Mexico, Albuquerque, NM, USA., Hunter R; Department of Pharmaceutical Sciences, University of New Mexico, Albuquerque, NM, USA., Salazar R; Department of Pharmaceutical Sciences, University of New Mexico, Albuquerque, NM, USA., Ottens AK; Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, VA, USA., Erdely A; Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, WV, USA., Gu H; College of Health Solutions, Arizona State University, Phoenix, AZ, USA.; Center for Translational Science, Florida International University, Port St. Lucie, FL, USA., Campen MJ; Department of Pharmaceutical Sciences, University of New Mexico, Albuquerque, NM, USA.

Publikováno v: Inhalation toxicology [Inhal Toxicol] 2023 Mar-Apr; Vol. 35 (3-4), pp. 86-100. Date of Electronic Publication: 2022 Jan 17.

Neuroinflammatory and Neurometabolomic Consequences From Inhaled Wildfire Smoke-Derived Particulate Matter in the Western United States.

Autor: Scieszka D; Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA., Hunter R; Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA., Begay J; Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA., Bitsui M; Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA., Lin Y; Department of Geography and Environmental Studies, College of Arts and Sciences, University of New Mexico, Albuquerque, New Mexico 87131, USA., Galewsky J; Department of Earth and Planetary Sciences, College of Arts and Sciences, University of New Mexico, Albuquerque, New Mexico 87131, USA., Morishita M; Department of Family Medicine, Michigan State University, East Lansing, Michigan 48824, USA., Klaver Z; Department of Family Medicine, Michigan State University, East Lansing, Michigan 48824, USA., Wagner J; College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA., Harkema JR; College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA., Herbert G; Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA., Lucas S; Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA., McVeigh C; Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA., Bolt A; Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA., Bleske B; Department of Pharmacy Practice and Administrative Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA., Canal CG; Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia 23298, USA., Mostovenko E; Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia 23298, USA., Ottens AK; Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia 23298, USA., Gu H; Arizona State University, Phoenix, Arizona, USA., Campen MJ; Department of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA., Noor S; Department of Neurosciences, School of Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA.

Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2022 Feb 28; Vol. 186 (1), pp. 149-162.

Pulmonary delivery of the broad-spectrum matrix metalloproteinase inhibitor marimastat diminishes multiwalled carbon nanotube-induced circulating bioactivity without reducing pulmonary inflammation.

Autor: Young TL; Department of Pharmaceutical Sciences, MSC09 5360, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA., Mostovenko E; Department of Anatomy and Neurobiology, Virginia Commonwealth University, PO Box 980709, Richmond, VA, 23298, USA., Denson JL; Department of Pharmaceutical Sciences, MSC09 5360, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA., Begay JG; Department of Pharmaceutical Sciences, MSC09 5360, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA., Lucas SN; Department of Pharmaceutical Sciences, MSC09 5360, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA., Herbert G; Department of Pharmaceutical Sciences, MSC09 5360, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA., Zychowski K; College of Nursing, University of New Mexico, Albuquerque, NM, 87131, USA., Hunter R; Department of Pharmaceutical Sciences, MSC09 5360, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA., Salazar R; Department of Pharmaceutical Sciences, MSC09 5360, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA., Wang T; Department of Internal Medicine, University of Arizona College of Medicine, Phoenix, AZ, USA., Fraser K; Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, WV, 26505, USA., Erdely A; Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, WV, 26505, USA., Ottens AK; Department of Anatomy and Neurobiology, Virginia Commonwealth University, PO Box 980709, Richmond, VA, 23298, USA., Campen MJ; Department of Pharmaceutical Sciences, MSC09 5360, 1 University of New Mexico, Albuquerque, NM, 87131-0001, USA. MCampen@salud.unm.edu.

Publikováno v: Particle and fibre toxicology [Part Fibre Toxicol] 2021 Sep 08; Vol. 18 (1), pp. 34. Date of Electronic Publication: 2021 Sep 08.

Secreted Peptides for Diagnostic Trajectory Assessments in Brain Injury Rehabilitation.

Autor: Patel PD; Virginia Commonwealth University, School of Medicine, Richmond, VA, USA., Stafflinger JE; Virginia Commonwealth University, School of Medicine, Richmond, VA, USA., Marwitz JH; Virginia Commonwealth University, School of Medicine, Richmond, VA, USA., Niemeier JP; Virginia Commonwealth University, School of Medicine, Richmond, VA, USA., Ottens AK; Virginia Commonwealth University, School of Medicine, Richmond, VA, USA.

Publikováno v: Neurorehabilitation and neural repair [Neurorehabil Neural Repair] 2021 Feb; Vol. 35 (2), pp. 169-184. Date of Electronic Publication: 2020 Dec 17.