Výsledky vyhledávání

Report

Uncertainty Quantification Using Ensemble Learning and Monte Carlo Sampling for Performance Prediction and Monitoring in Cell Culture Processes

Autor: Khuat, Thanh Tung, Bassett, Robert, Otte, Ellen, Gabrys, Bogdan

Biopharmaceutical products, particularly monoclonal antibodies (mAbs), have gained prominence in the pharmaceutical market due to their high specificity and efficacy. As these products are projected to constitute a substantial portion of global pharm

Externí odkaz: http://arxiv.org/abs/2409.02149

Zobrazit plný text záznamu

Report

Applications of Machine Learning in Biopharmaceutical Process Development and Manufacturing: Current Trends, Challenges, and Opportunities

Autor: Khuat, Thanh Tung, Bassett, Robert, Otte, Ellen, Grevis-James, Alistair, Gabrys, Bogdan

While machine learning (ML) has made significant contributions to the biopharmaceutical field, its applications are still in the early stages in terms of providing direct support for quality-by-design based development and manufacturing of biopharmac

Externí odkaz: http://arxiv.org/abs/2310.09991

Zobrazit plný text záznamu

Report

Multi-fidelity Gaussian Process for Biomanufacturing Process Modeling with Small Data

Autor: Sun, Yuan, Nathan-Roberts, Winton, Pham, Tien Dung, Otte, Ellen, Aickelin, Uwe

In biomanufacturing, developing an accurate model to simulate the complex dynamics of bioprocesses is an important yet challenging task. This is partially due to the uncertainty associated with bioprocesses, high data acquisition cost, and lack of da

Externí odkaz: http://arxiv.org/abs/2211.14493

Zobrazit plný text záznamu