Mechanistic Characterization of Cancer-associated Fibroblast Depletion via an Antibody-Drug Conjugate Targeting Fibroblast Activation Protein.

Autor: Gallant JP; Molecular and Cellular Pharmacology Program, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Hintz HM; Department of Pharmacology, University of Minnesota School of Medicine, Minneapolis, Minnesota., Gunaratne GS; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Breneman MT; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Recchia EE; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., West JL; Molecular and Cellular Pharmacology Program, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Ott KL; Molecular and Cellular Pharmacology Program, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Heninger E; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Jackson AE; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Luo NY; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Rosenkrans ZT; Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Hernandez R; Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Zhao SG; University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Lang JM; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Meimetis L; Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Kosoff D; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; William S Middleton Memorial Veterans' Hospital, Madison, Wisconsin., LeBeau AM; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; University of Wisconsin Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.; Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

Publikováno v: Cancer research communications [Cancer Res Commun] 2024 Jun 12; Vol. 4 (6), pp. 1481-1494.