Zobrazeno 1 - 10 of 34 pro vyhledávání: '"Ott GR"'
1
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
2
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
3
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
5
Akademický článek
Novel Macrocyclic Antagonists of the Calcitonin Gene-Related Peptide Receptor: Design, Realization, and Structural Characterization of Protein-Ligand Complexes.
Autor: Cansfield AD; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Ator MA; Teva Pharmaceuticals, 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Banerjee J; Syngene International, Biocon Park, Bommasandra, Bangalore 560099, India., Bestwick M; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Bortolato A; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Brown GA; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Brown J; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Butkovic K; Fidelta d.o.o., Prilaz Baruna Filipovića 29, 10000 Zagreb, Croatia., Cansfield JE; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Christopher JA; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Congreve M; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Cseke G; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Deflorian F; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Dugan B; Teva Pharmaceuticals, 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Hunjadi MP; Fidelta d.o.o., Prilaz Baruna Filipovića 29, 10000 Zagreb, Croatia., Hutinec A; Fidelta d.o.o., Prilaz Baruna Filipovića 29, 10000 Zagreb, Croatia., Inturi TK; Syngene International, Biocon Park, Bommasandra, Bangalore 560099, India., Landek G; Fidelta d.o.o., Prilaz Baruna Filipovića 29, 10000 Zagreb, Croatia., Mason J; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., O'Brien A; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Ott GR; Teva Pharmaceuticals, 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Rupcic R; Fidelta d.o.o., Prilaz Baruna Filipovića 29, 10000 Zagreb, Croatia., Saxty G; Fidelta d.o.o., Prilaz Baruna Filipovića 29, 10000 Zagreb, Croatia., Southall SM; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Zadravec R; Fidelta d.o.o., Prilaz Baruna Filipovića 29, 10000 Zagreb, Croatia., Watson SP; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K.
Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2022 Mar 16; Vol. 13 (6), pp. 751-765. Date of Electronic Publication: 2022 Mar 04.
Zobrazit plný text záznamu
6
Akademický článek
Structure-Based Drug Discovery of N -(( R )-3-(7-Methyl-1 H -indazol-5-yl)-1-oxo-1-((( S )-1-oxo-3-(piperidin-4-yl)-1-(4-(pyridin-4-yl)piperazin-1-yl)propan-2-yl)amino)propan-2-yl)-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3- d ][1,3]oxazine]-1-carboxamide (HTL22562): A Calcitonin Gene-Related Peptide Receptor Antagonist for Acute Treatment of Migraine.
Autor: Bucknell SJ; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Ator MA; Teva Pharmaceuticals, 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Brown AJH; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Brown J; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Cansfield AD; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Cansfield JE; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Christopher JA; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Congreve M; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Cseke G; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Deflorian F; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Jones CR; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Mason JS; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., O'Brien MA; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Ott GR; Teva Pharmaceuticals, 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Pickworth M; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K., Southall SM; Sosei Heptares, Steinmetz Building, Granta Park, Great Abington, Cambridge CB21 6DG, U.K.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2020 Jul 23; Vol. 63 (14), pp. 7906-7920. Date of Electronic Publication: 2020 Jul 08.
Zobrazit plný text záznamu
7
Akademický článek
Combined inhibition of atypical PKC and histone deacetylase 1 is cooperative in basal cell carcinoma treatment.
Autor: Mirza AN; Program in Epithelial Biology and Department of Dermatology, Stanford University School of Medicine, Stanford, California, USA., Fry MA; Children's Hospital Oakland Research Institute, Oakland, California, USA., Urman NM; Program in Epithelial Biology and Department of Dermatology, Stanford University School of Medicine, Stanford, California, USA., Atwood SX; Program in Epithelial Biology and Department of Dermatology, Stanford University School of Medicine, Stanford, California, USA., Roffey J; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London, United Kingdom., Ott GR; Teva Branded Pharmaceutical Products R&D, West Chester, Pennsylvania, USA., Chen B; Institute for Computational Health Sciences, UCSF, San Francisco, California, USA., Lee A; Children's Hospital Oakland Research Institute, Oakland, California, USA., Brown AS; Program in Epithelial Biology and Department of Dermatology, Stanford University School of Medicine, Stanford, California, USA., Aasi SZ; Program in Epithelial Biology and Department of Dermatology, Stanford University School of Medicine, Stanford, California, USA., Hollmig T; Program in Epithelial Biology and Department of Dermatology, Stanford University School of Medicine, Stanford, California, USA., Ator MA; Teva Branded Pharmaceutical Products R&D, West Chester, Pennsylvania, USA., Dorsey BD; Teva Branded Pharmaceutical Products R&D, West Chester, Pennsylvania, USA., Ruggeri BR; Teva Branded Pharmaceutical Products R&D, West Chester, Pennsylvania, USA., Zificsak CA; Teva Branded Pharmaceutical Products R&D, West Chester, Pennsylvania, USA., Sirota M; Institute for Computational Health Sciences, UCSF, San Francisco, California, USA., Tang JY; Program in Epithelial Biology and Department of Dermatology, Stanford University School of Medicine, Stanford, California, USA.; Children's Hospital Oakland Research Institute, Oakland, California, USA., Butte A; Institute for Computational Health Sciences, UCSF, San Francisco, California, USA., Epstein E; Children's Hospital Oakland Research Institute, Oakland, California, USA., Sarin KY; Program in Epithelial Biology and Department of Dermatology, Stanford University School of Medicine, Stanford, California, USA., Oro AE; Program in Epithelial Biology and Department of Dermatology, Stanford University School of Medicine, Stanford, California, USA.
Publikováno v: JCI insight [JCI Insight] 2017 Nov 02; Vol. 2 (21). Date of Electronic Publication: 2017 Nov 02.
Zobrazit plný text záznamu
8
Akademický článek
Pyrrolo[2,1-f][1,2,4]triazines: From C-nucleosides to kinases and back again, the remarkable journey of a versatile nitrogen heterocycle.
Autor: Ott GR; Discovery & Product Development, Teva Global R&D, 145 Brandywine Parkway, West Chester, PA 19380, United States. Electronic address: gregory.ott@tevapharm.com., Favor DA; Discovery & Product Development, Teva Global R&D, 145 Brandywine Parkway, West Chester, PA 19380, United States.
Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2017 Sep 15; Vol. 27 (18), pp. 4238-4246. Date of Electronic Publication: 2017 Jul 30.
Zobrazit plný text záznamu
9
Akademický článek
Technically Extended MultiParameter Optimization (TEMPO): An Advanced Robust Scoring Scheme To Calculate Central Nervous System Druggability and Monitor Lead Optimization.
Autor: Ghose AK; Discovery and Product Development, Teva Branded Pharmaceutical Products R&D, Inc. , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Ott GR; Discovery and Product Development, Teva Branded Pharmaceutical Products R&D, Inc. , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Hudkins RL; Discovery and Product Development, Teva Branded Pharmaceutical Products R&D, Inc. , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States.
Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2017 Jan 18; Vol. 8 (1), pp. 147-154. Date of Electronic Publication: 2016 Oct 26.
Zobrazit plný text záznamu
10
Akademický článek
Discovery of Clinical Candidate CEP-37440, a Selective Inhibitor of Focal Adhesion Kinase (FAK) and Anaplastic Lymphoma Kinase (ALK).
Autor: Ott GR; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Cheng M; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Learn KS; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Wagner J; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Gingrich DE; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Lisko JG; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Curry M; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Mesaros EF; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Ghose AK; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Quail MR; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Wan W; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Lu L; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Dobrzanski P; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Albom MS; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Angeles TS; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Wells-Knecht K; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Huang Z; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Aimone LD; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Bruckheimer E; Champions Oncology, Inc. , One University Plaza, Suite 307, Hackensack, New Jersey 07601, United States., Anderson N; Champions Oncology, Inc. , One University Plaza, Suite 307, Hackensack, New Jersey 07601, United States., Friedman J; Champions Oncology, Inc. , One University Plaza, Suite 307, Hackensack, New Jersey 07601, United States., Fernandez SV; Thomas Jefferson University , 233 South 10th Street, 1002 BLSB, Philadelphia, Pennsylvania 19107, United States., Ator MA; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Ruggeri BA; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States., Dorsey BD; Teva Branded Pharmaceutical Products R&D , 145 Brandywine Parkway, West Chester, Pennsylvania 19380, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2016 Aug 25; Vol. 59 (16), pp. 7478-96. Date of Electronic Publication: 2016 Aug 15.
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje