Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Otoya Ueda"'
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0305012 (2024)
Pre-messenger RNA (pre-mRNA) splicing modulation is an attractive approach for investigating the mechanisms of genetic disorders caused by mis-splicing. Previous reports have indicated that a modified U7 small nuclear RNA (U7 snRNA) is a prospective
Externí odkaz:
https://doaj.org/article/53a44f268cb741618b4f6d025f52495b
Autor:
Manami Iida, Shuichi Ohtomo, Naoko A. Wada, Otoya Ueda, Yoshinori Tsuboi, Atsuo Kurata, Kou-ichi Jishage, Naoshi Horiba
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Claudin-1 (CL-1) is responsible for the paracellular barrier function of glomerular parietal epithelial cells (PEC) in kidneys, but the role of CL-1 in proximal tubules remains to be elucidated. In this study, to evaluate CL-1 as a potential therapeu
Externí odkaz:
https://doaj.org/article/51f4917714924b249a9605b2f93c6e8a
Autor:
Taku Fukuzawa, Masanori Fukazawa, Otoya Ueda, Hideaki Shimada, Aki Kito, Mami Kakefuda, Yosuke Kawase, Naoko A Wada, Chisato Goto, Naoshi Fukushima, Kou-Ichi Jishage, Kiyofumi Honda, George L King, Yoshiki Kawabe
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56681 (2013)
Although excessive fructose intake is epidemiologically linked with dyslipidemia, obesity, and diabetes, the mechanisms regulating plasma fructose are not well known. Cells transfected with sodium/glucose cotransporter 5 (SGLT5), which is expressed e
Externí odkaz:
https://doaj.org/article/c273d1438edf4164a6e71434670c0f05
Autor:
Tomo Mukai, Hiroko Segawa, Shohei Sasaki, Saori Ohnishi, Yasuko Ishikawa, Naoshi Horiba, Otoya Ueda, Kou-ichi Jishage, Naoshi Fukushima, Sawako Tatsumi, Shinsuke Kido, Ken-ichi Miyamoto
Publikováno v:
Kidney Research and Clinical Practice, Vol 31, Iss 2, p A59 (2012)
Hyperphosphatemia is recognized as a contributor to vascular calcification in patients with chronic kidney disease (CKD) and hemodialysis (HD) patients and is independently associated with cardiac mortality. Dietary inorganic phosphorus (Pi) restrict
Externí odkaz:
https://doaj.org/article/10d409c8574d400da9bfec3adfdf15a6
Autor:
Tomoyuki Igawa, Takehisa Kitazawa, Yoshiki Kawabe, Kou-ichi Jishage, Mika Endo, Yoshito Nakanishi, Otoya Ueda, Atsuhiko Kato, Noriaki Sawada, Yasushi Tomii, Fumihisa Isomura, Masaki Kamimura, Tetsuya Wakabayashi, Ami Ito, Haruka Kuroi, Junko Shinozuka, Yuki Noguchi, Motohiko Sato, Yasuko Satoh, Nasa Savory, Sotaro Naoi, Koki Hamada, Ayano Hirako, Sayuri Horikawa, Akihisa Sakamoto, Shun-ichiro Komatsu, Shojiro Kadono, Tomochika Matsushita, Tetsushi Sakiyama, Kenji Adachi, Natsuki Ono, Tatsuhiko Tachibana, Hirofumi Mikami, Shun Shimizu, Yuki Ohte, Naoko A. Wada, Taro Miyazaki, Shoichi Metsugi, Meiri Shida-Kawazoe, Kenji Taniguchi, Naoka Hironiwa, Masaki Honda, Ryo Uchikawa, Takayuki Nemoto, Yuji Hori, Yoshinori Narita, Mika Kamata-Sakurai
Supplementary figures, tables, material and methods, and references
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef075e9b136326aba4e8a3303859f52
https://doi.org/10.1158/2159-8290.22535753.v1
https://doi.org/10.1158/2159-8290.22535753.v1
Autor:
Tatsuhiko Tachibana, Nasa Savory, Otoya Ueda, Sayuri Horikawa, Tetsushi Sakiyama, Tomochika Matsushita, Yuji Hori, Kou-ichi Jishage, Haruka Kuroi, Motohiko Sato, Tetsuya Wakabayashi, Junko Shinozuka, Naoka Hironiwa, Meiri Shida-Kawazoe, Kenji Adachi, Ryo Uchikawa, Taro Miyazaki, Koki Hamada, Masaki Honda, Fumihisa Isomura, Mika Endo, Mika Kamata-Sakurai, Yoshito Nakanishi, Yuki Noguchi, Natsuki Ono, Yasuko Satoh, Yuki Ohte, Tomoyuki Igawa, Ayano Hirako, Hirofumi Mikami, Naoko A. Wada, Noriaki Sawada, Takehisa Kitazawa, Yasushi Tomii, Shun-ichiro Komatsu, Takayuki Nemoto, Yoshinori Narita, Kenji Taniguchi, Shun Shimizu, Naoi Sotaro, Akihisa Sakamoto, Shojiro Kadono, Yoshiki Kawabe, Atsuhiko Kato, Kamimura Masaki, Shoichi Metsugi, Ami Ito
Publikováno v:
Cancer Discovery. 11:158-175
Agonistic antibodies targeting CD137 have been clinically unsuccessful due to systemic toxicity. Because conferring tumor selectivity through tumor-associated antigen limits its clinical use to cancers that highly express such antigens, we exploited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a70e3edd07d12527043287be739925bc
https://doi.org/10.1158/2159-8290.cd-20-0328
https://doi.org/10.1158/2159-8290.cd-20-0328
Autor:
Toru Fujii, Akira Maeda, Sumire Sasaki, Sawako Tatsumi, Hiroko Segawa, Ruri Kirino, Shohei Sasaki, Yasuhiro Ichida, Miwa Noguchi, Ai Hanazaki, Aoi Kushi, Yosuke Kawase, Otoya Ueda, Ichiro Kaneko, Naoshi Horiba, Hiromi Tateishi, Kayo Ikuta, Naoko A. Wada, Mami Kakefuda, Kou-ichi Jishage, Ken-ichi Miyamoto, Shuichi Ohtomo, Yuka Kawabata
Publikováno v:
Clinical and Experimental Nephrology. 22:517-528
Hyperphosphatemia is common in chronic kidney disease and is associated with morbidity and mortality. The intestinal Na+-dependent phosphate transporter Npt2b is thought to be an important molecular target for the prevention of hyperphosphatemia. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71595e3c7a5297e9a0828ca221ef28ca
https://doi.org/10.1007/s10157-017-1497-3
https://doi.org/10.1007/s10157-017-1497-3
Autor:
Mizuho Noguchi, Tsuneo Ito, Etsuko Fujii, Takahiro Ishiguro, Kou-ichi Jishage, Yasuko Kinoshita, Hiromi Tateishi, Kiyoharu Sato, Hiroshi Hino, Kunihiro Hattori, Atsuhiko Kato, Otoya Ueda, Masahiro Morita, Jun-ichi Nezu, Chisato Goto, Kaoru Matsumoto, Yosuke Kawase, Naoko A. Wada, Mami Kakefuda
Publikováno v:
Scientific Reports. 8
Correction to: Scientific Reports 7: Article number: 45839; published online: 03 April 2017; updated: 19 March 2018 In this Article, the Authors neglected to include the Data and Material Availability section. This section should read: “Data and ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::725281730f44c0c308d142dc1f1a9cb5
https://doi.org/10.1038/srep46960
https://doi.org/10.1038/srep46960
Autor:
Yui Fujita, Toshio Doi, Taichi Murakami, Yumi Kangawa, Kou Ichi Jishage, Otoya Ueda, Naoshi Fukushima, Seiji Kishi, Hideharu Abe, Yumiko Saga, Kojiro Nagai, Tatsuya Tominaga, Yashpal S. Kanwar
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Podocyte injury has been proposed to play an important role in diabetic nephropathy; however, its pathological mechanism remains unclear. We have shown that bone morphogenetic protein 4 (BMP4) signaling leads to the glomerular changes characteristic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb73c9f03e71688b83ff238bb06c86d
https://pubmed.ncbi.nlm.nih.gov/30158674
https://pubmed.ncbi.nlm.nih.gov/30158674
Autor:
Hiroshi Hino, Etsuko Fujii, Jun-ichi Nezu, Tsuneo Ito, Kaoru Matsumoto, Takahiro Ishiguro, Yosuke Kawase, Hiromi Tateishi, Mizuho Noguchi, Yasuko Kinoshita, Kiyoharu Sato, Masahiro Morita, Naoko A. Wada, Mami Kakefuda, Kou-ichi Jishage, Chisato Goto, Otoya Ueda, Kunihiro Hattori, Atsuhiko Kato
Publikováno v:
Scientific Reports
T cell–mediated immunotherapy is an attractive strategy for treatment in various disease areas. In this therapeutic approach, the CD3 complex is one of the key molecules to modulate T cell functions; however, in many cases, we cannot evaluate the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f21229ad90d2461170ebb703f0c76e49
http://europepmc.org/articles/PMC5377452
http://europepmc.org/articles/PMC5377452