Three-Coordinate Copper(II) Alkynyl Complex in C–C Bond Formation: The Sesquicentennial of the Glaser Coupling

Autor: Otome E. Okoromoba, Jeffery A. Bertke, Christine Greene, Timothy H. Warren, Mahdi Raghibi Boroujeni, Abolghasem Bakhoda

Publikováno v: Journal of the American Chemical Society. 142:18483-18490

Copper(II) alkynyl species are proposed as key intermediates in numerous Cu-catalyzed C-C coupling reactions. Supported by a β-diketiminate ligand, the three-coordinate copper(II) alkynyl [CuII]-C≡CAr (Ar = 2,6-Cl2C6H3) forms upon reaction of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43151faee709acbf97ca48b0b9aca25e
https://doi.org/10.1021/jacs.0c07137

Bromofluorination of unsaturated compounds using DMPU/HF as a fluorinating reagent

Autor: Bo Xu, Shengzong Liang, Francis J. Barrios, Otome E. Okoromoba, Zofia Hetman, Gerald B. Hammond

Publikováno v: Journal of Fluorine Chemistry. 203:136-139

Bromofluorination reactions were performed by treating of a variety of unsaturated compounds with N-bromosuccinimide (NBS) and DMPU/HF as the fluorinating reagent. The DMPU/HF complex showed to be an efficient fluorinating reagent to convert alkenes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4dfc7d0708edc834f7e9755c0be69de
https://doi.org/10.1016/j.jfluchem.2017.07.016

Copper Catalyzed sp3 C-H α-Acetylation

Autor: Timothy H. Warren, Otome E. Okoromoba, Eun Sil Jang, Thomas R. Cundari, Claire L. McMullin

α-substituted ketones are important chemical targets as synthetic intermediates as well as functionalities in in natural products and pharmaceuticals. We report the sp3 C-H α-acetylation of sp3 C-H substrates R-H with arylmethyl ketones ArC(O)Me to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59ce75847aa6edc6c3e6e6ea623592b2
https://doi.org/10.26434/chemrxiv.11407116.v1

Metal-Free and User-Friendly Regioselective Hydroxyfluorination of Olefins

Autor: Santos Fustero, Gerald B. Hammond, Pablo Barrio, Bo Xu, Nanako Kobayashi, Daniel M. Sedgwick, Raquel Román, Inés López, Otome E. Okoromoba

Publikováno v: ORGANIC LETTERS
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)

A simple, user-friendly, metal-free protocol for the regioselective anti-Markovnikov hydrofluorination of olefins using readily available and inexpensive reagents has been developed. This new approach displays a broader scope than previously reported

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f89edd9f71b934d6d9d815361727859
https://fundanet.cipf.es/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=1204

ChemInform Abstract: Preparation of Fluorinated Tetrahydropyrans and Piperidines Using a New Nucleophilic Fluorination Reagent DMPU/HF

Autor: Bo Xu, Otome E. Okoromoba, Gerald B. Hammond

Publikováno v: ChemInform. 47

DMPU/HF (HF content 65 wt %/wt) is an ideal nucleophilic fluorination reagent for the diastereoselective synthesis of substituted 4-fluorotetrahydropyrans and 4-fluoropiperidines via a fluoro-Prins reaction. When compared to classical nucleophilic fl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6429ed1bf3a3a7deb28b9e1f372becf1
https://doi.org/10.1002/chin.201602034