Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Otolaryngology/Audiology"'
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 12, p e14260 (2010)
PLoS ONE, Vol 5, Iss 12, p e14260 (2010)
Animal models continue to improve our understanding of tinnitus pathogenesis and aid in development of new treatments. However, there are no diagnostic biomarkers for tinnitus-related pathophysiology for use in awake, freely moving animals. To addres
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14317 (2010)
PLoS ONE
PLoS ONE
TRPML3, a member of the transient receptor potential (TRP) family, is an inwardly rectifying, non-selective Ca2+-permeable cation channel that is regulated by extracytosolic Na+ and H+ and can be activated by a variety of small molecules. The severe
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5 (7), pp.e11845. ⟨10.1371/journal.pone.0011845⟩
PLoS ONE, Vol 5, Iss 7, p e11845 (2010)
PLoS ONE, Public Library of Science, 2010, 5 (7), pp.e11845. ⟨10.1371/journal.pone.0011845⟩
PLoS ONE, Vol 5, Iss 7, p e11845 (2010)
Background: Frequent oulomotricity problems with orthoptic testing were reported in patients with tinnitus. This study examines with objective recordings vergence eye movements in patients with somatic tinnitus patients with ability to modify their s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::287e12a735efc6d4cbb7bbadac540841
https://hal.archives-ouvertes.fr/hal-02384248
https://hal.archives-ouvertes.fr/hal-02384248
Autor:
Dhasakumar Navaratnam, Joseph Santos-Sacchi, Mohamed Uduman, Steven H. Kleinstein, Jamie L. Duke, Corey S. Frucht
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11502 (2010)
PLoS ONE
PLoS ONE
Background Auditory hair cells spontaneously regenerate following injury in birds but not mammals. A better understanding of the molecular events underlying hair cell regeneration in birds may allow for identification and eventually manipulation of r
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10101 (2010)
PLoS ONE
PLoS ONE
The capability of processing rapid fluctuations in the temporal envelope of sound declines with age and this contributes to older adults' difficulties in understanding speech. Although, changes in central auditory processing during aging have been pr
Autor:
José G. Pichel, Lourdes Rodriguez-de la Rosa, Hortensia Sánchez-Calderón, Marta Milo, Matthew C. Holley, Isabel Varela-Nieto
Publikováno v:
PLoS One
PLoS ONE, Vol 5, Iss 1, p e8699 (2010)
PLoS ONE
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS ONE, Vol 5, Iss 1, p e8699 (2010)
PLoS ONE
Digital.CSIC. Repositorio Institucional del CSIC
instname
17 páginas, 8 figuras.-- et al.
[Background]: Insulin-like growth factor-I (IGF-I) provides pivotal cell survival and differentiation signals during inner ear development throughout evolution. Homozygous mutations of human IGF1 cause syndromic
[Background]: Insulin-like growth factor-I (IGF-I) provides pivotal cell survival and differentiation signals during inner ear development throughout evolution. Homozygous mutations of human IGF1 cause syndromic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8af8d6596062bb539cc62e979c21110
Autor:
María Rodríguez Aburto, Isabel Varela-Nieto, Ulf R. Rapp, Carmen Muñoz-Agudo, Hortensia Sánchez-Calderón, Marta Magariños
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14435 (2010)
PLoS ONE
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS ONE
Digital.CSIC. Repositorio Institucional del CSIC
instname
[Background]: Early inner ear development requires the strict regulation of cell proliferation, survival, migration and differentiation, coordinated by the concerted action of extrinsic and intrinsic factors. Deregulation of these processes is associ
Autor:
Yoko Nakano, Yuzhou Zhang, Richard J.H. Smith, Botond Banfi, Hyoung-Mi Kim, Daniel C. Marcus, Sung Huhn Kim, Joel D. Sanneman, Randy Alan Nessler, Philine Wangemann
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 5, Iss 8, p e1000610 (2009)
PLoS Genetics, Vol 5, Iss 8, p e1000610 (2009)
Hereditary hearing loss is one of the most common birth defects, yet the majority of genes required for audition is thought to remain unidentified. Ethylnitrosourea (ENU)–mutagenesis has been a valuable approach for generating new animal models of
Autor:
Ian N. M. Day, W.H. Irwin McLean, Raquel Granell, George Davey Smith, Santiago Rodriguez, Alan D. Irvine, Colin N. A. Palmer, Amanda Hall, John Henderson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 6, p e5784 (2009)
PLoS ONE, Vol 4, Iss 6, p e5784 (2009)
BACKGROUND: Filaggrin is a major protein in the epidermis. Several mutations in the filaggrin gene (FLG) have been associated with a number of conditions. Filaggrin is expressed in the tympanic membrane and could alter its mechanical properties, but
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 3, p e5026 (2009)
PLoS ONE, Vol 4, Iss 3, p e5026 (2009)
BACKGROUND: Tinnitus is a frequent condition with high morbidity and impairment in quality of life. The pathophysiology is still incompletely understood. Electromagnetic fields are discussed to be involved in the multi-factorial pathogenesis of tinni