Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Otila Dumetrescu"'
Autor:
Barbara Grant, Andrew D. Zelenetz, A. Dimitrios Colevas, Paul A. Hamlin, Carol S. Portlock, Michael D. Stubblefield, David J. Straus, Craig H. Moskowitz, Otila Dumetrescu, Owen A. O'Connor
Publikováno v:
British journal of haematology. 143(2)
The epothilones represent a novel group of microtubule stabilization agents that appear to retain activity even in chemotherapy-resistant cell lines and animal models. Because of their ability to overcome chemotherapy resistance, we conducted a phase
Autor:
Debra M. Sarasohn, Andrew D. Zelenetz, Martin Fleischer, Otila Dumetrescu, Barbara MacGregor-Cortelli, Craig H. Moskowitz, Diane R. Mould, Steven M. Horwitz, Ariela Noy, Paul A. Hamlin, Frank Sirotnak, Owen A. O'Connor, David J. Straus, Ellen Neylon, Carol S. Portlock
Publikováno v:
British journal of haematology. 139(3)
T-cell lymphomas (TCLs) are characterised by poor responses to therapy with brief durations of remissions. An early phase study of pralatrexate has demonstrated dramatic activity in patients with relapsed/refractory disease. Of the first 20 lymphoma
Autor:
Owen A. O'Connor, Elizabeth Trehu, David J. Straus, Michael D. Stubblefield, John J. Wright, Jamie Muzzy, Paul A. Hamlin, Otila Dumetrescu, Dixie Lee Esseltine, Julian Adams, Carol S. Portlock, Craig H. Moskowitz, Andrew D. Zelenetz, Barbara MacGregor-Cortelli, David P. Schenkein, Elizabeth Choi
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 23(4)
Purpose To determine the antitumor activity of the novel proteasome inhibitor bortezomib in patients with indolent and mantle-cell lymphoma (MCL). Patients and Methods Patients with indolent and MCL were eligible. Bortezomib was given at a dose of 1.
Autor:
J. Pappanicolou, Diane R. Mould, Paul A. Hamlin, Ariela Noy, Martin Fleischer, Otila Dumetrescu, John F. Gerecitano, Debra M. Sarasohn, Chaya S. Moskowitz, Andrew D. Zelenetz, Frank Sirotnak, Ellen Neylon, Owen A. O'Connor, Steve Horwitz, David J. Straus, Carol S. Portlock, Michael Saunders
Publikováno v:
Blood. 108:400-400
T-cell lymphomas (TCL) represent a diverse and heterogeneous group of diseases. The prognosis of patients with TCL is generally much worse than for patients with B-cell lymphoma (BCL). Pralatrexate is a novel 10-deazaminopoterin rationally designed t