Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Othon J. Mena"'
Autor:
Andrew L. Frelinger, Robin L. Haynes, Richard D. Goldstein, Michelle A. Berny-Lang, Anja J. Gerrits, Molly Riehs, Elisabeth A. Haas, Brankica Paunovic, Othon J. Mena, Steven C. Campman, Ginger L. Milne, Lynn A. Sleeper, Hannah C. Kinney, Alan D. Michelson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Sudden infant death syndrome (SIDS) is the leading cause of post-neonatal infant mortality, but the underlying cause(s) are unclear. A subset of SIDS infants has abnormalities in the neurotransmitter, serotonin (5-hydroxytryptamine [5-HT]) a
Externí odkaz:
https://doaj.org/article/3c59b8e94be64128b9d6845b97a05786
Autor:
Robin L Haynes, Felicia Trachtenberg, Ryan Darnall, Elisabeth A Haas, Richard D Goldstein, Othon J Mena, Henry F Krous, Hannah C Kinney
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 82:467-482
The sudden infant death syndrome (SIDS), the leading cause of postneonatal infant mortality in the United States, is typically associated with a sleep period. Previously, we showed evidence of serotonergic abnormalities in the medulla (e.g. altered s
Autor:
Olafur Sveinsson, Othon J. Mena, Janice Drabek, Cory A Massey, Elisabeth A. Haas, Samantha J Thompson, Ryan W Ostrom, Alica M. Goldman, Jeffrey L. Noebels, Torbjörn Tomson
Publikováno v:
Brain Communications
Sudden Unexpected Death in Epilepsy is a leading cause of epilepsy-related mortality, and the analysis of mouse Sudden Unexpected Death in Epilepsy models is steadily revealing a spectrum of inherited risk phenotypes based on distinct genetic mechani
Autor:
Annapurna Poduri, Ingrid A. Holm, Jonathan R. Lucas, Christopher H. Thompson, Othon J. Mena, Hannah C. Kinney, Catherine A. Brownstein, Elisabeth A. Haas, Robin L. Haynes, Matthew N. Bainbridge, Richard D. Goldstein, Alfred L. George, Emma K. Giles, Bethann Schaber, Beth Rosen Sheidley
Publikováno v:
Epilepsia. 59:e56-e62
We identified SCN1A variants in two infants who died of Sudden Infant Death Syndrome (SIDS) from an exome sequencing study of 10 cases of SIDS with hippocampal abnormalities but no history of seizures. One harbored SCN1A G682V, and the other had two
Autor:
Steven K White, Elizabeth A Bundock, Othon J Mena, Orrin Devinsky, Daniel Friedman, Daniel S. Atherton, Dale C. Hesdorffer, Mitchel Morey, Zian H. Tseng, Elizabeth J. Donner, Torbjörn Tomson, Owen Middleton, Cyndi Wright, Niu Tian, Aileen McCrillis, David J. Thurman, Heather S Jarrell
Publikováno v:
Academic forensic pathology, vol 8, iss 1
Epilepsia, vol 59, iss 3
Epilepsia, vol 59, iss 3
Sudden unexpected death of an individual with epilepsy (SUDEP) can pose a challenge to death investigators, as most deaths are unwitnessed and the individual is commonly found dead in bed. Anatomic findings (e.g., tongue/lip bite) are commonly absent
Autor:
Andrew L. Frelinger, Elisabeth A. Haas, Hoa Tran, Harry P.W. Kozakewich, Hannah C. Kinney, Khosrow Adeli, David S. Paterson, Robin L. Haynes, Alan D. Michelson, Richard D. Goldstein, Gerard T. Berry, Anja J. Gerrits, Felicia L. Trachtenberg, Emma K. Giles, Othon J. Mena
Publikováno v:
Proceedings of the National Academy of Sciences. 114:7695-7700
Sudden infant death syndrome (SIDS), the leading cause of postneonatal infant mortality, likely comprises heterogeneous disorders with the common phenotype of sudden death without explanation upon postmortem investigation. Previously, we reported tha
Publikováno v:
Australian Journal of Forensic Sciences. 48:37-41
Toxicology testing revealed dramatic increases in whole-blood concentrations of verapamil and diphenhydramine in the short time between hospital admission and death (53 min) in a subject (with a history of overdosing) found unresponsive. While some d
Autor:
Ingvar J. Rognum, Robin L. Haynes, Keith Hyland, Hoa Tran, David S. Paterson, Elisabeth A. Haas, Kevin G. Broadbelt, Hannah C. Kinney, Brian J. Harty, Othon J. Mena, Henry F. Krous
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 73:115-122
Forensic biomarkers are needed in sudden infant death syndrome (SIDS) to help identify this group among other sudden unexpected deaths in infancy. Previously, we reported multiple serotonergic (5-HT) abnormalities in nuclei of the medulla oblongata t
Autor:
Lisa A. Teot, Othon J. Mena, Beata Hargitai, Walter L. Kemp, Catherine A. Brownstein, Harry S. Abram, Robin L. Haynes, Richard D. Goldstein, Simon K. Warfield, Dawna D. Armstrong, Jane B. Cryan, Michael C. Kruer, Ingrid A. Holm, Sanjay P. Prabhu, Elisabeth A. Haas, Lynn A. Sleeper, Gerald T. Berry, Hannah C. Kinney, Annapurna Poduri, Joanne Gastrang, Roya Dastjerdi
Publikováno v:
Journal of neuropathology and experimental neurology. 75(10)
Sudden infant death syndrome (SIDS) and sudden unexplained death in childhood (SUDC) are defined as sudden death in a child remaining unexplained despite autopsy and death scene investigation. They are distinguished from each other by age criteria, i
Publikováno v:
American Journal of Forensic Medicine & Pathology. 32:55-57
We present the case of a 7-month-old female infant who was found crying and limp. She was transported to a hospital where a possible subarachnoid hemorrhage was diagnosed radiologically. Before further studies could be pursued, her condition worsened