Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Otgontuya Ganbaatar"'
Autor:
Tomohiro Okagawa, Satoru Konnai, Shinya Goto, Yamato Sajiki, Otgontuya Ganbaatar, Kei Watari, Hayato Nakamura, Cai-Xia Wang, Taro Tachibana, Yukinari Kato, Yayoi Kameda, Junko Kohara, Nobuhiro Terasaki, Manabu Kubota, Akira Takeda, Hirofumi Takahashi, Yasuhiko Suzuki, Naoya Maekawa, Shiro Murata, Kazuhiko Ohashi
Publikováno v:
Veterinary Research, Vol 54, Iss 1, Pp 1-14 (2023)
Abstract Immune checkpoint molecules PD-1/PD-L1 cause T-cell exhaustion and contribute to disease progression in chronic infections of cattle. We established monoclonal antibodies (mAbs) that specifically inhibit the binding of bovine PD-1/PD-L1; how
Externí odkaz:
https://doaj.org/article/d1e0e81c1ed349c095a5bc6af2dd26e6
Autor:
Otgontuya Ganbaatar, Satoru Konnai, Tomohiro Okagawa, Yutaro Nojima, Naoya Maekawa, Yoshiki Ichikawa, Atsushi Kobayashi, Tomoyuki Shibahara, Yojiro Yanagawa, Hidetoshi Higuchi, Yukinari Kato, Yasuhiko Suzuki, Shiro Murata, Kazuhiko Ohashi
Publikováno v:
Immunity, Inflammation and Disease, Vol 9, Iss 4, Pp 1573-1583 (2021)
Abstract Introduction Chronic infections lead to the functional exhaustion of T cells. Exhausted T cells are phenotypically differentiated by the surface expression of the immunoinhibitory receptor, such as programmed death‐1 (PD‐1). The inhibito
Externí odkaz:
https://doaj.org/article/c1781704b73940e2bfc77036577955b1
Autor:
Tomohiro Okagawa, Satoru Konnai, Hayato Nakamura, Otgontuya Ganbaatar, Yamato Sajiki, Kei Watari, Haruka Noda, Mitsuru Honma, Yukinari Kato, Yasuhiko Suzuki, Naoya Maekawa, Shiro Murata, Kazuhiko Ohashi
Publikováno v:
Vaccines, Vol 11, Iss 3, p 559 (2023)
Interactions between programmed death 1 (PD-1) and PD-ligand 1 (PD-L1) cause functional exhaustion of T cells by inducing inhibitory signals, thereby attenuating effector functions of T cells. We have developed an anti-bovine PD-L1 blocking antibody
Externí odkaz:
https://doaj.org/article/9b1ef7c06a6e4dc39be8f67a5c02b2b4
Autor:
Otgontuya Ganbaatar, Satoru Konnai, Tomohiro Okagawa, Yutaro Nojima, Naoya Maekawa, Erina Minato, Atsushi Kobayashi, Ryo Ando, Nobuya Sasaki, Daisuke Miyakoshi, Osamu Ichii, Yukinari Kato, Yasuhiko Suzuki, Shiro Murata, Kazuhiko Ohashi
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0234218 (2020)
Programmed death-1 (PD-1) is an immunoinhibitory receptor expressed on lymphocytes. Interaction of PD-1 with its ligand PD-ligand 1 (PD-L1) delivers inhibitory signals and impairs proliferation, cytokine production, and cytotoxicity of T cells. In ou
Externí odkaz:
https://doaj.org/article/af45bb119142484c9b3fe705289e8a4d
Autor:
Wisa Tiyamanee, Satoru Konnai, Tomohiro Okagawa, Yutaro Nojima, Otgontuya Ganbaatar, Naoya Maekawa, Rie Hasebe, Yumiko Kagawa, Yukinari Kato, Yasuhiko Suzuki, Shiro Murata, Kazuhiko Ohashi
Publikováno v:
Veterinary Immunology and Immunopathology. 261:110609
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f646c592110d71466c363023ae70a0cd
https://doi.org/10.1016/j.vetimm.2023.110609
https://doi.org/10.1016/j.vetimm.2023.110609
Autor:
Satoru Konnai, Tomohiro Okagawa, Yojiro Yanagawa, Atsushi Kobayashi, Otgontuya Ganbaatar, Tomoyuki Shibahara, Yutaro Nojima, Shiro Murata, Hidetoshi Higuchi, Kazuhiko Ohashi, Yoshiki Ichikawa, Yasuhiko Suzuki, Yukinari Kato, Naoya Maekawa
Publikováno v:
Immunity, Inflammation and Disease, Vol 9, Iss 4, Pp 1573-1583 (2021)
Immunity, Inflammation and Disease
Immunity, Inflammation and Disease
Introduction Chronic infections lead to the functional exhaustion of T cells. Exhausted T cells are phenotypically differentiated by the surface expression of the immunoinhibitory receptor, such as programmed death‐1 (PD‐1). The inhibitory signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b32672b93180158284b478e6d03153
https://doi.org/10.1002/iid3.510
https://doi.org/10.1002/iid3.510
Autor:
Tomohiro Okagawa, Nobuya Sasaki, Satoru Konnai, Shiro Murata, Daisuke Miyakoshi, Atsushi Kobayashi, Naoya Maekawa, Yutaro Nojima, Otgontuya Ganbaatar, Osamu Ichii, Ryo Ando, Erina Minato, Kazuhiko Ohashi, Yasuhiko Suzuki, Yukinari Kato
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0234218 (2020)
PLoS ONE
PLoS ONE
Programmed death-1 (PD-1) is an immunoinhibitory receptor expressed on exhausted T cells during chronic illness. Interaction of PD-1 with its ligand PD-ligand 1 (PD-L1) delivers inhibitory signals and impairs proliferation, cytokine production, and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca6548b0fd37544b44476e619e9607e
https://doaj.org/article/af45bb119142484c9b3fe705289e8a4d
https://doaj.org/article/af45bb119142484c9b3fe705289e8a4d
Autor:
Shiro Murata, Fumi Kayasaki, Hayato Nakamura, Mitsuru Honma, Honami Shimakura, Haruka Noda, Kazuhiko Ohashi, Erina Minato, Satoru Konnai, Yamato Sajiki, Akira Takeda, Atsushi Kobayashi, Manabu Kubota, Shinya Goto, Otgontuya Ganbaatar, Junko Kohara, Tomohiro Okagawa, Naoya Maekawa, Nobuhiro Terasaki, Kei Watari
Publikováno v:
Veterinary Microbiology. 254:108976
Diarrhea is a major cause of death in calves and this is linked directly to economic loss in the cattle industry. Fermented milk replacer (FMR) has been used widely in clinical settings for calf feeding to improve its health and growth. However, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7077af5d9aa010187da49126b631dcd
https://doi.org/10.1016/j.vetmic.2020.108976
https://doi.org/10.1016/j.vetmic.2020.108976