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pro vyhledávání: '"Otília Menyhart"'
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274662 (2022)
[This corrects the article DOI: 10.1371/journal.pone.0245824.].
Externí odkaz:
https://doaj.org/article/669898d023814a74918beac23621a8e4
MultipleTesting.com: A tool for life science researchers for multiple hypothesis testing correction.
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0245824 (2021)
Scientists from nearly all disciplines face the problem of simultaneously evaluating many hypotheses. Conducting multiple comparisons increases the likelihood that a non-negligible proportion of associations will be false positives, clouding real dis
Externí odkaz:
https://doaj.org/article/263f61f414544e018ceb151307966ae4
Akademický článek
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Publikováno v:
F1000Research. 12:418
Background Gene co-expression correlations frequently signal shared biological functions with coordinated regulation. We hypothesized that maintained correlations might be essential for cellular survival, representing potential vulnerabilities of can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::797e4a19be84569879117664c58eb8d7
https://doi.org/10.12688/f1000research.131414.1
https://doi.org/10.12688/f1000research.131414.1
Autor:
Otília Menyhárt, Balázs Győrffy
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 949-960 (2021)
While cost-effective high-throughput technologies provide an increasing amount of data, the analyses of single layers of data seldom provide causal relations. Multi-omics data integration strategies across different cellular function levels, includin
Externí odkaz:
https://doaj.org/article/08595476bfc346ee841e18d80234c4e0
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Despite much effort on the treatment of breast cancer over the decades, a great uncertainty regarding the appropriate molecular biomarkers and optimal therapeutic strategy still exists. This research was performed to analyze the a
Externí odkaz:
https://doaj.org/article/7d01c18eb9584990b234e8225a963cde
Autor:
Otília Menyhárt, Balázs Győrffy
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 5, Pp 990-1005 (2019)
Abstract SHH‐activated medulloblastomas (SHH‐MB) account for 25–30% of all medulloblastomas (MB) and occur with a bimodal age distribution, encompassing many infant and adult, but fewer childhood cases. Different age groups are characterized by
Externí odkaz:
https://doaj.org/article/b04223d41e6746698e71c630f021ebaf
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-17 (2019)
Abstract Childhood medulloblastomas (MB) are heterogeneous and are divided into four molecular subgroups. The provisional non-wingless-activated (WNT)/non-sonic hedgehog-activated (SHH) category combining group 3 and group 4 represents over two third
Externí odkaz:
https://doaj.org/article/cc456ab3a0634542b83ef7e7e8709bef
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2019)
The immunotherapy agent pembrolizumab has been approved for gastric cancer (GC) patients with recurrent or advanced disease who are PD-L1 positive. Mutations in the primary lesion may drive the expression of immune targets thereby priming the tumor t
Externí odkaz:
https://doaj.org/article/683915b769cd4d2eaf589f282c0ad7c9
Publikováno v:
Royal Society Open Science, Vol 5, Iss 12 (2018)
Background: Potential prognostic biomarker candidates for hepatocellular carcinoma (HCC) are abundant, but their generalizability is unexplored. We cross-validated markers of overall survival (OS) and vascular invasion in independent datasets. Method
Externí odkaz:
https://doaj.org/article/4dbe3480ec064d4eb5e832d016ef15a7