Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Otávio de Melo Espíndola"'
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Externí odkaz:
https://doaj.org/article/f7143a6178b747319f277fccdbb25680
Autor:
Nicole Lardini Freitas, Yago Côrtes Pinheiro Gomes, Flávia dos Santos Souza, Rafael Carvalho Torres, Juliana Echevarria-Lima, Ana Claudia Celestino Bezerra Leite, Marco Antonio Sales Dantas Lima, Abelardo Queiroz Campos Araújo, Marcus Tulius Teixeira Silva, Otávio de Melo Espíndola
Publikováno v:
Viruses, Vol 14, Iss 10, p 2146 (2022)
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a neurodegenerative disease that leads to motor impairment due to a chronic inflammatory process in the central nervous system (CNS). However, the HAM/TSP pathogenesis is not comp
Externí odkaz:
https://doaj.org/article/d5e848e726f74bb8b8a8da435a4ff3af
Autor:
Otávio de Melo Espíndola, Marilda Siqueira, Cristiane Nascimento Soares, Marco Antonio Sales Dantas de Lima, Ana Claudia Celestino Bezerra Leite, Abelardo Queiroz Campos Araujo, Carlos Otávio Brandão, Marcus Tulius Teixeira Silva
Publikováno v:
International Journal of Infectious Diseases, Vol 96, Iss , Pp 567-569 (2020)
We report that patients with COVID-19 displaying distinct neurological disorders have undetectable or extremely low levels of SARS-CoV-2 RNA in the cerebrospinal fluid, indicating that viral clearance precede the neurological involvement. This findin
Externí odkaz:
https://doaj.org/article/9ee78fc994ac4f888bdacb636bb5cc25
Autor:
Caio Thomaz, Cintia Xavier de Mello, Otávio de Melo Espíndola, Armando de Oliveira Shubach, Leonardo Pereira Quintella, Raquel Vasconcelos Carvalhaes de Oliveira, Adriane Corrêa Gomes Duarte, Maria Inês Fernandes Pimentel, Marcelo Rosandiski Lyra, Mauro Celio de Almeida Marzochi
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0243978 (2021)
BackgroundCutaneous leishmaniasis (CL) is an infectious vector-borne disease caused by protozoa of the Leishmania genus that affects humans and animals. The distribution of parasites in the lesion is not uniform, and there are divergences in the lite
Externí odkaz:
https://doaj.org/article/06de12750125454bbb12ec4da2e1b7e5
Autor:
Otávio de Melo Espíndola, Esther Siteur-van Rijnstra, Esmay Frankin, Kees Weijer, Yme Ubeles van der Velden, Ben Berkhout, Bianca Blom, Julien Villaudy
Publikováno v:
Cells, Vol 10, Iss 10, p 2514 (2021)
Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy of CD4+ T-cells associated with HTLV-1 infection. In this study, we used the model of immunodeficient NSG mice reconstituted with a functional human immune system (HIS) to investigate
Externí odkaz:
https://doaj.org/article/1ed3b594db9c4b3a8ace1167fd2d9719
Autor:
Zilton Vasconcelos, Claudia Raja Gabaglia, Luana Damasceno, Patrícia Brasil, Myrna C. Bonaldo, Thomas Jaenisch, James D. Cherry, Liege Maria Abreu de Carvalho, Boris Pastorino, Andrea Zin, Maria Elisabeth Lopes Moreira, Otávio de Melo Espíndola, Denise Cotrim da Cunha, Marcos Vinicius da Silva Pone, Karin Nielsen-Saines, Raquel de Vasconcellos Carvalhaes de Oliveira, Sheila Moura Pone, Xavier de Lamballerie, Ieda Pereira Ribeiro
Publikováno v:
J Infect Dis.
J Infect Dis
J Infect Dis
Background Zika virus (ZIKV) is associated with severe congenital abnormalities and laboratory diagnosis of antenatal infection is difficult. Here we evaluated ZIKV neutralizing antibody (nAb) kinetics in infants born to mothers with PCR-confirmed ZI
Autor:
Leticia Guida, Elizabeth de Souza Neves, Otávio de Melo Espíndola, Leonardo Henrique Ferreira Gomes, Danielle Nascimento Rocha, André Luiz Land Curi, Maria Regina Reis Amendoeira
Publikováno v:
Parasitology Research. 120:763-767
Toxoplasmosis is the most prevalent zoonosis in the world and is associated with a large spectrum of diseases. Acute acquired toxoplasmosis (AAT) is considered a benign and self-limiting disease but severe postnatal infections have been reported, par
Autor:
Marco A. Lima, Otávio de Melo Espíndola, Cristiane Nascimento Soares, Marcus Tulius T. Silva, Abelardo Q.C. Araújo, Ana Claudia Celestino Bezerra Leite, Renan Amaral Coutinho, Livia Afonso, Henrique Souza Barros de Oliveira
Publikováno v:
Journal of NeuroVirology
COVID-19 pandemic revealed several neurological syndromes related to this infection. We describe the clinical, laboratory, and radiological features of eight patients with COVID-19 who developed peripheral facial palsy during infection. In three pati
Autor:
Ketiuce de Azevedo Zukeram, Chris Smith, Cláudio Tadeu Daniel-Ribeiro, Otávio de Melo Espíndola, James A. G. Whitworth, Isabella Campos Vargas de Moraes, Michele Fernanda Borges da Silva, Stephanie Lema Suarez Penetra, Mia Ferreira Araujo, Claudia Raja Gabaglia, Maria Ogrzewalska, Trevon L Fuller, Mayumi Duarte Wakimoto, Myrna C. Bonaldo, Renata Serrano Lopes, Anielle da Pina-Costa, Alex Pauvolid-Corrêa, Heloisa F P Santos, Ighor Arantes, Guilherme Amaral Calvet, Paola Cristina Resende, Larissa R Lira-Silva, Lusiele Guaraldo, Karin Nielsen-Saines, Ana Beatriz Machado Lima, Marilda M. Siqueira, Patrícia Brasil
Publikováno v:
International Journal of Infectious Diseases
International Journal of Infectious Diseases, Vol 114, Iss, Pp 58-61 (2022)
International Journal of Infectious Diseases, Vol 114, Iss, Pp 58-61 (2022)
We describe a case of prolonged COVID-19 caused by the SARS-CoV-2 Gamma variant in a fully vaccinated healthcare worker, 387 days after an infection caused by lineage B.1.1.33. Infections were confirmed by whole-genome sequencing and corroborated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e1574b081a6817d3caa564ba3cf0fb
https://researchonline.lshtm.ac.uk/id/eprint/4663436/7/Penetra_etal_2021_Post-acute-covid-19-syndrome.pdf
https://researchonline.lshtm.ac.uk/id/eprint/4663436/7/Penetra_etal_2021_Post-acute-covid-19-syndrome.pdf
Autor:
Marcus Tulius T. Silva, Ana Claudia Celestino Bezerra Leite, Marco A. Lima, Isaac Lima Silva Filho, Yago Côrtes Pinheiro Gomes, Otávio de Melo Espíndola, Abelardo Q.C. Araújo, Ana Carolina Paulo Vicente
Publikováno v:
Journal of General Virology. 102
Human T-lymphotropic virus type 1 (HTLV-1) provirus expression is mainly directed by Tax-responsive elements (TRE) within the long terminal repeats (LTR). Mutations in TRE can reduce provirus expression and since a high proviral load (PVL) is a risk