Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Oswaldo L. Castro"'
Autor:
Sergei Nekhai, Min Xu, Altreisha Foster, Ishmael Kasvosve, Sharmin Diaz, Roberto F. Machado, Oswaldo L. Castro, Gregory J. Kato, James G. Taylor, Victor R. Gordeuk
Publikováno v:
Haematologica, Vol 98, Iss 3 (2013)
Ferroportin Q248H mutation has an allele frequency of 2.2–13.4% in African populations and is associated with a mild tendency to increased serum ferritin in the general population. Some investigators have reported that ferroportin Q248H is degraded
Externí odkaz:
https://doaj.org/article/a6b6f2ba26804914837fbe8a6611129d
Autor:
Mehdi Nouraie, Janet S. Lee, Yingze Zhang, Tamir Kanias, Xuejun Zhao, Zeyu Xiong, Timothy B. Oriss, Qilu Zeng, Gregory J. Kato, J. Simon R. Gibbs, Mariana E. Hildesheim, Vandana Sachdev, Robyn J. Barst, Roberto F. Machado, Kathryn L. Hassell, Jane A. Little, Dean E. Schraufnagel, Lakshmanan Krishnamurti, Enrico Novelli, Reda E. Girgis, Claudia R. Morris, Erika Berman Rosenzweig, David B. Badesch, Sophie Lanzkron, Oswaldo L. Castro, Jonathan C. Goldsmith, Victor R. Gordeuk, Mark T. Gladwin
Publikováno v:
Haematologica, Vol 98, Iss 3 (2013)
The intensity of hemolytic anemia has been proposed as an independent risk factor for the development of certain clinical complications of sickle cell disease, such as pulmonary hypertension, hypoxemia and cutaneous leg ulceration. A composite variab
Externí odkaz:
https://doaj.org/article/6186f62dfbe0472a8d73981f8e61f9fb
Autor:
Craig A. Sable, Zakari Y. Aliyu, Niti Dham, Mehdi Nouraie, Vandana Sachdev, Stanislav Sidenko, Galina Y. Miasnikova, Lydia A. Polyakova, Adelina I. Sergueeva, Daniel J. Okhotin, Vladimir Bushuev, Alan T. Remaley, Xiaomei Niu, Oswaldo L. Castro, Mark T. Gladwin, Gregory J. Kato, Josef T. Prchal, Victor R. Gordeuk
Publikováno v:
Haematologica, Vol 97, Iss 2 (2012)
Background Patients with Chuvash polycythemia, (homozygosity for the R200W mutation in the von Hippel Lindau gene (VHL)), have elevated levels of hypoxia inducible factors HIF-1 and HIF-2, often become iron-deficient secondary to phlebotomy, and have
Externí odkaz:
https://doaj.org/article/d9c537e8b8aa4aeb95cb987b860a82cf
Autor:
Mehdi Nouraie, Kevin Cheng, Xiaomei Niu, Evadne Moore-King, Margaret F. Fadojutimi-Akinsi, Caterina P. Minniti, Craig Sable, Sohail Rana, Niti Dham, Andrew Campbell, Gregory Ensing, Gregory J. Kato, Mark T. Gladwin, Oswaldo L. Castro, Victor R. Gordeuk
Publikováno v:
Haematologica, Vol 96, Iss 8 (2011)
Background Bone changes are common in sickle cell disease, but the pathogenesis is not fully understood. Tartrate-resistant acid phosphatase (TRACP) type 5b is produced by bone-resorbing osteoclasts. In other forms of hemolytic anemia, increased iron
Externí odkaz:
https://doaj.org/article/38b5671823ab413bbbb46c59b858d75c
Autor:
Victor R. Gordeuk, Caterina P. Minniti, Mehdi Nouraie, Andrew D. Campbell, Sohail R Rana, Lori Luchtman-Jones, Craig Sable, Niti Dham, Gregory Ensing, Josef T. Prchal, Gregory J. Kato, Mark T. Gladwin, Oswaldo L. Castro
Publikováno v:
Haematologica, Vol 96, Iss 1 (2011)
Background While in adults with sickle cell disease an elevation of tricuspid regurgitation velocity is associated with increased mortality, the importance of this finding in children has not been established. The role of intravascular hemolysis in t
Externí odkaz:
https://doaj.org/article/cbad73da1b0c4536a05c08bc395f9984
Autor:
Caterina P. Minniti, Craig Sable, Andrew Campbell, Sohail Rana, Gregory Ensing, Niti Dham, Onyinye Onyekwere, Mehdi Nouraie, Gregory J. Kato, Mark T. Gladwin, Oswaldo L. Castro, Victor R. Gordeuk
Publikováno v:
Haematologica, Vol 94, Iss 3 (2009)
Background Elevation of echocardiography-determined tricuspid regurgitant jet velocity predicts high systolic pulmonary artery pressure and early mortality in adults with sickle cell disease. The definition, prevalence and clinical correlates of elev
Externí odkaz:
https://doaj.org/article/62000928e9b94706bd4371703dc45de4
Autor:
Gregory J. Kato, Niti Dham, Mehdi Nouraie, Andrew D. Campbell, Manuel Arteta, Victor R. Gordeuk, Caterina P. Minniti, Deepika S. Darbari, James G. Taylor, Lori Luchtman-Jones, Mark T. Gladwin, Gregory J. Ensing, Sohail Rana, Sergei Nekhai, Oswaldo L. Castro, Craig Sable
Publikováno v:
Am J Hematol
In the US, mortality in sickle cell disease (SCD) increases after age 18–20 years. Biomarkers of mortality risk can identify patients who need intensive follow-up and early or novel interventions. We prospectively enrolled 510 SCD patients aged 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f306716ac5190cde0f75a6037ed77337
https://doi.org/10.1002/ajh.25799
https://doi.org/10.1002/ajh.25799
Autor:
Mark T Gladwin, Robyn J Barst, J Simon R Gibbs, Mariana Hildesheim, Vandana Sachdev, Mehdi Nouraie, Kathryn L Hassell, Jane A Little, Dean E Schraufnagel, Lakshmanan Krishnamurti, Enrico Novelli, Reda E Girgis, Claudia R Morris, Erika Berman Rosenzweig, David B Badesch, Sophie Lanzkron, Oswaldo L Castro, James G Taylor, Jonathan C Goldsmith, Gregory J Kato, Victor R Gordeuk, Roberto F Machado, walk-PHaSST Investigators and Patients
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e99489 (2014)
The role of pulmonary hypertension as a cause of mortality in sickle cell disease (SCD) is controversial.We evaluated the relationship between an elevated estimated pulmonary artery systolic pressure and mortality in patients with SCD. We followed pa
Externí odkaz:
https://doaj.org/article/36ede0ae221943d1887a84c560bea8cc
Autor:
Victor R, Gordeuk, Binal N, Shah, Xu, Zhang, Philip E, Thuma, Stenford, Zulu, Rodgers, Moono, N Scott, Reading, Jihyun, Song, Yingze, Zhang, Mehdi, Nouraie, Andrew, Campbell, Caterina P, Minniti, Sohail R, Rana, Deepika S, Darbari, Gregory J, Kato, Mei, Niu, Oswaldo L, Castro, Roberto, Machado, Mark T, Gladwin, Josef T, Prchal
Publikováno v:
Am J Hematol
Genetic modifiers of anemia in Plasmodium falciparum infection and sickle cell disease (SCD) are not fully known. Both conditions are associated with oxidative stress, hemolysis and anemia. The CYB5R3 gene encodes cytochrome b5 reductase 3, which con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3978aaa9edd44ac9c6513c4d1ce13eb1
https://pubmed.ncbi.nlm.nih.gov/32697331
https://pubmed.ncbi.nlm.nih.gov/32697331
Autor:
Xiaomei Niu, Mehdi Nouraie, Andrew Campbell, Sohail Rana, Caterina P Minniti, Craig Sable, Deepika Darbari, Niti Dham, N Scott Reading, Josef T Prchal, Gregory J Kato, Mark T Gladwin, Oswaldo L Castro, Victor R Gordeuk
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7956 (2009)
BACKGROUND:Pulmonary hypertension and left ventricular diastolic dysfunction are complications of sickle cell disease. Pulmonary hypertension is associated with hemolysis and hypoxia, but other unidentified factors are likely involved in pathogenesis
Externí odkaz:
https://doaj.org/article/bd4d922f8353415780c2d3a51668442b