Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Oswaldo G. Rodriguez-Mora"'
Publikováno v:
Antioxidants & Redox Signaling. 8:1807-1817
Oxygen radicals have diverse effects on cells. In many cases, exposure to reactive oxygen intermediates (ROI) can induce cell death. Conversely, there is also evidence that suggests oxygen radicals can activate signaling pathways that are thought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::852ada8e063e6cf1341bf003496bc724
https://doi.org/10.1089/ars.2006.8.1807
https://doi.org/10.1089/ars.2006.8.1807
Autor:
Kawana S White, M. J. Evans, Richard A. Franklin, Kovacs Cj, Michelle M. LaHair, Claudio Sibata, James A. McCubrey, Oswaldo G. Rodriguez-Mora, Ron R. Allison
Publikováno v:
Cancer Biology & Therapy. 5:1022-1030
Many cancer treatments induce cell death through lethal oxidative stress. Oxidative stress also induces the activation of the calcium/calmodulin-dependent kinases (CaM-Ks), CaM-KII and CaM-KIV. In turn, the CaM-Ks are known to induce the activation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69aecce8b0f02631710deaed2e67e6c
https://doi.org/10.4161/cbt.5.8.2910
https://doi.org/10.4161/cbt.5.8.2910
Autor:
Christopher J. Howe, Michelle M. LaHair, James A. McCubrey, Richard A. Franklin, Oswaldo G. Rodriguez-Mora
Publikováno v:
Expert Opinion on Therapeutic Targets. 9:791-808
In this review the authors discuss the expression and activation of a family of protein kinases known as the calcium/calmodulin-dependent kinases (CaM-kinase) and the role that these kinases have in the activation of antiapoptotic signalling pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23acd74d2a1dd678f7d6db51a521d930
https://doi.org/10.1517/14728222.9.4.791
https://doi.org/10.1517/14728222.9.4.791
Autor:
Oswaldo G. Rodriguez-Mora, Christopher J. Howe, Richard A. Franklin, James A. McCubrey, Michelle M. LaHair
Publikováno v:
Free Radical Biology and Medicine. 38:1653-1661
Hydrogen peroxide (HP) induced the phosphorylation of cAMP response element binding protein (CREB) on Ser133 in Jurkat T lymphocytes via p38 and MSK1. Although CREB Ser133 was phosphorylated, increases in HP-stimulated CREB-mediated transcription wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5559b4a055d638431ebac4da3f284160
https://doi.org/10.1016/j.freeradbiomed.2005.02.035
https://doi.org/10.1016/j.freeradbiomed.2005.02.035
Autor:
James A. McCubrey, Richard A. Franklin, Christopher J. Howe, Oswaldo G. Rodriguez-Mora, Michelle M. LaHair, Penni J. Robinson
Publikováno v:
ASSAY and Drug Development Technologies. 1:537-544
We investigated two model systems to study anergy in a human T cell line. OKT3 or calcium ionophore stimulation of Jurkat cells, in the absence of costimulation, resulted in a steep reduction in the transcription and secretion of IL-2 in response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18939ae80aea48539bf09fff5dded3b2
https://doi.org/10.1089/154065803322302790
https://doi.org/10.1089/154065803322302790
Publikováno v:
Cancer research. 65(12)
Calcium is universally required for cell growth and proliferation. Calmodulin is the main intracellular receptor for calcium. Although calcium and calmodulin are well known to be required for cell cycle regulation, the target pathways for their actio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5db716781b8004188f8248161a7e92
https://pubmed.ncbi.nlm.nih.gov/15958590
https://pubmed.ncbi.nlm.nih.gov/15958590
Publikováno v:
Cancer Biology & Therapy. 2:354-355
Commentary to:mda-7 (IL-24) Inhibits Growth and Enhances Radiosensitivity of Glioma Cells In Vitro via JNK SignalingAdly Yacoub, Clint Mitchell, Irina V. Lebedeva, Devanand Sarkar, Zao-Zhong Su, Robert McKinstry, Rahul V. Gopalkrishnan, Steven Grant,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66411432d87d1a44fc97f5f32e095e28
https://doi.org/10.4161/cbt.2.4.438
https://doi.org/10.4161/cbt.2.4.438
Activation of the Calcium/Calmodulin-Dependent Protein Kinases as a Consequence of Oxidative Stress.
Publikováno v:
Antioxidants & Redox Signaling; Sep2006, Vol. 8 Issue 9/10, p1807-1817, 11p