Small-molecule inhibition of SARS-CoV-2 NSP14 RNA cap methyltransferase.

Autor: Meyer C; Laboratory for RNA Molecular Biology, The Rockefeller University, New York, NY, USA., Garzia A; Laboratory for RNA Molecular Biology, The Rockefeller University, New York, NY, USA., Miller MW; Sanders Tri-Institutional Therapeutics Discovery Institute, The Rockefeller University, New York, NY, USA., Huggins DJ; Sanders Tri-Institutional Therapeutics Discovery Institute, The Rockefeller University, New York, NY, USA.; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY, USA., Myers RW; Sanders Tri-Institutional Therapeutics Discovery Institute, The Rockefeller University, New York, NY, USA., Hoffmann HH; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA., Ashbrook AW; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA., Jannath SY; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA., Liverton N; Sanders Tri-Institutional Therapeutics Discovery Institute, The Rockefeller University, New York, NY, USA., Kargman S; Sanders Tri-Institutional Therapeutics Discovery Institute, The Rockefeller University, New York, NY, USA., Zimmerman M; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Nelson AM; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Sharma V; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Dolgov E; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Cangialosi J; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Penalva-Lopez S; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Alvarez N; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Chang CW; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA.; Department of Medicine, Division of Infectious Diseases, Columbia University, New York, NY, USA., Oswal N; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Gonzalez I; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Rasheed R; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Goldgirsh K; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Davis JA; Laboratory for RNA Molecular Biology, The Rockefeller University, New York, NY, USA., Ramos-Espiritu L; Fisher Drug Discovery Resource Center, The Rockefeller University, New York, NY, USA., Menezes MR; Fisher Drug Discovery Resource Center, The Rockefeller University, New York, NY, USA., Larson C; Fisher Drug Discovery Resource Center, The Rockefeller University, New York, NY, USA., Nitsche J; PROTEROS Biostructures GmbH, Planegg-Martinsried, Germany., Ganichkin O; PROTEROS Biostructures GmbH, Planegg-Martinsried, Germany., Alwaseem H; Proteomics Resource Center, The Rockefeller University, New York, NY, USA., Molina H; Proteomics Resource Center, The Rockefeller University, New York, NY, USA., Steinbacher S; PROTEROS Biostructures GmbH, Planegg-Martinsried, Germany., Glickman JF; Fisher Drug Discovery Resource Center, The Rockefeller University, New York, NY, USA., Perlin DS; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA., Rice CM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA., Meinke PT; Sanders Tri-Institutional Therapeutics Discovery Institute, The Rockefeller University, New York, NY, USA., Tuschl T; Laboratory for RNA Molecular Biology, The Rockefeller University, New York, NY, USA. ttuschl@rockefeller.edu.

Publikováno v: Nature [Nature] 2024 Dec 11. Date of Electronic Publication: 2024 Dec 11.

The Influence of Body Fat Dynamics on Pulmonary Immune Responses in Murine Tuberculosis: Unraveling Sex-Specific Insights.

Autor: Dhanyalayam D; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA., Thangavel H; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA., Sidrat T; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA., Oswal N; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA., Lizardo K; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA., Mauro M; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA., Zhao X; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA., Xue HH; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA., Desai JV; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA., Nagajyothi JF; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 21; Vol. 25 (13). Date of Electronic Publication: 2024 Jun 21.

High-Throughput Behavioral Aging and Lifespan Assays Using the Lifespan Machine.

Autor: Del Carmen-Fabregat A; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST); Universitat Pompeu Fabra (UPF)., Sedlackova L; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST)., Oswal N; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST); Universitat Pompeu Fabra (UPF)., Stroustrup N; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST); Universitat Pompeu Fabra (UPF); nicholas.stroustrup@crg.eu.

Publikováno v: Journal of visualized experiments : JoVE [J Vis Exp] 2024 Jan 26 (203). Date of Electronic Publication: 2024 Jan 26.

IgA Determines Bacterial Composition in the Gut.

Autor: Gupta S; Mucosa Immunology Laboratory, National Institute of Immunology, New Delhi, India.; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA., Gupta SL; Mucosa Immunology Laboratory, National Institute of Immunology, New Delhi, India.; Department of Pediatrics, Division of Infectious Disease, School of Medicine, Emory University, Atlanta, Georgia, USA., Singh A; Mucosa Immunology Laboratory, National Institute of Immunology, New Delhi, India., Oswal N; Mucosa Immunology Laboratory, National Institute of Immunology, New Delhi, India.; Center for Discovery and Innovation, Hackensack University Medical Center, Nutley, New Jersey, USA., Bal V; Mucosa Immunology Laboratory, National Institute of Immunology, New Delhi, India.; Indian Institute of Science Education and Research, Pune, India., Rath S; Mucosa Immunology Laboratory, National Institute of Immunology, New Delhi, India.; Translational Health Science and Technology Institute, Faridabad, India., George A; Mucosa Immunology Laboratory, National Institute of Immunology, New Delhi, India., Basu S; Mucosa Immunology Laboratory, National Institute of Immunology, New Delhi, India.; Department of Medicine, Weill Cornell Medicine, New York, New York, USA.

Publikováno v: Crohn's & colitis 360 [Crohns Colitis 360] 2023 May 26; Vol. 5 (3), pp. otad030. Date of Electronic Publication: 2023 May 26 (Print Publication: 2023).

Children's SARS-CoV-2 Infection and Their Vaccination.

Autor: Gupta SL; National Institute of Immunology, New Delhi 110067, India., Tyagi R; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China., Dhar A; National Institute of Immunology, New Delhi 110067, India., Oswal N; National Institute of Immunology, New Delhi 110067, India., Khandelwal A; Jhalawar Medical College, Jhalawar 326001, India., Jaiswal RK; Department of Cancer Biology, Cardinal Bernardin Cancer Center, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.

Publikováno v: Vaccines [Vaccines (Basel)] 2023 Feb 12; Vol. 11 (2). Date of Electronic Publication: 2023 Feb 12.