Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Osvaldo Yañez"'
Autor:
Kevin Taype-Huanca, Manuel I. Osorio, Diego Inostroza, Luis Leyva-Parra, Lina Ruíz, Ana Valderrama-Negrón, Jesús Alvarado-Huayhuaz, Osvaldo Yañez, William Tiznado
Publikováno v:
Biophysica, Vol 4, Iss 2, Pp 182-194 (2024)
This study explored the inhibitory potential of gallium maltolate against severe acute respiratory syndrome coronavirus 2 and main and papain-like proteases. Computational methods, including density functional theory and molecular docking, were used
Externí odkaz:
https://doaj.org/article/3631f23a8bcd4da3bf4a22a4c62d393a
Autor:
Roger Espinosa-Saez, Sara M. Robledo, Tatiana Pineda, Javier Murillo, César Zúñiga, Osvaldo Yañez, Plinio Cantero-López, Alex Saez-Vega, Camilo Guzmán-Teran
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract In this study, six analogs of 2-arylquinoline were synthesized and evaluated for their in vitro and in vivo antiplasmodial and leishmanicidal activity. At a later stage, hemolytic activity and druggability were tested in vitro and in silico,
Externí odkaz:
https://doaj.org/article/aba95f9bcd404416bedaef8f97b1ee5e
Autor:
Diego Inostroza, Luis Leyva-Parra, Osvaldo Yañez, Andrew L. Cooksy, Venkatesan S. Thimmakondu, William Tiznado
Publikováno v:
Chemistry, Vol 5, Iss 3, Pp 1535-1545 (2023)
This study scrutinizes the complexities of designing and exploring the potential energy surfaces of systems containing more than twenty atoms with planar tetracoordinate carbons (ptCs). To tackle this issue, we utilized an established design rule to
Externí odkaz:
https://doaj.org/article/8379e50b417d49b4921777a434e28b82
Autor:
Francisco Altimiras, Leonardo Pavéz, Alireza Pourreza, Osvaldo Yañez, Lisdelys González-Rodríguez, José García, Claudio Galaz, Andrés Leiva-Araos, Héctor Allende-Cid
Publikováno v:
Agronomy, Vol 14, Iss 3, p 613 (2024)
In agricultural production, it is fundamental to characterize the phenological stage of plants to ensure a good evaluation of the development, growth and health of crops. Phenological characterization allows for the early detection of nutritional def
Externí odkaz:
https://doaj.org/article/95bedfdea6f544048a74b0b8b7130abd
Autor:
Diego Inostroza, Luis Leyva-Parra, Osvaldo Yañez, José Solar-Encinas, Alejandro Vásquez-Espinal, Maria Luisa Valenzuela, William Tiznado
Publikováno v:
Atoms, Vol 11, Iss 3, p 56 (2023)
Here, we present evidence that the D2h M2C50/2+ (M = Li-K, Be-Ca, Al-In, and Zn) species comprises planar hexacoordinate carbon (phC) structures that exhibit four covalent and two electrostatic interactions. These findings have been made possible usi
Externí odkaz:
https://doaj.org/article/feced9c699644e98903492b5d3e3afb3
Autor:
José Solar-Encinas, Alejandro Vásquez-Espinal, Luis Leyva-Parra, Osvaldo Yañez, Diego Inostroza, Maria Luisa Valenzuela, Walter Orellana, William Tiznado
Publikováno v:
Molecules, Vol 28, Iss 1, p 236 (2022)
Here, it is shown that the M3B12 (M = Cu-Au) clusters’ global minima consist of an elongated planar B12 fragment connected by an in-plane linear M3 fragment. This result is striking since this B12 planar structure is not favored in the bare cluster
Externí odkaz:
https://doaj.org/article/7177d2dfeff64294bfd032078f23e6f6
Autor:
Walter Orellana, Ricardo Pino-Rios, Osvaldo Yañez, Alejandro Vásquez-Espinal, Francesca Peccati, Julia Contreras-García, Carlos Cardenas, William Tiznado
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
We computationally explore an alternative to stabilize one-dimensional (1D) silicon-lithium nanowires (NWs). The Li12Si9 Zintl phase exhibits the NW [Li6Si5]∞1, combined with Y-shaped Si4 structures. Interestingly, this NW could be assembled from t
Externí odkaz:
https://doaj.org/article/0135f35894d945bca87da2d19f5ea79b
Autor:
Osvaldo Yañez, Manuel Isaías Osorio, Carlos Areche, Alejandro Vasquez-Espinal, Jessica Bravo, Angélica Sandoval-Aldana, José M. Pérez-Donoso, Fernando González-Nilo, Maria João Matos, Edison Osorio, Olimpo García-Beltrán, William Tiznado
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 140, Iss , Pp 111764- (2021)
Cocoa beans contain antioxidant molecules with the potential to inhibit type 2 coronavirus (SARS-CoV-2), which causes a severe acute respiratory syndrome (COVID-19). In particular, protease. Therefore, using in silico tests, 30 molecules obtained fro
Externí odkaz:
https://doaj.org/article/6fcab25d03e0492c9fa5c0f483560e92
Autor:
Osvaldo Yañez, Manuel Isaías Osorio, Eugenio Uriarte, Carlos Areche, William Tiznado, José M. Pérez-Donoso, Olimpo García-Beltrán, Fernando González-Nilo
Publikováno v:
Frontiers in Chemistry, Vol 8 (2021)
The pandemic that started in Wuhan (China) in 2019 has caused a large number of deaths, and infected people around the world due to the absence of effective therapy against coronavirus 2 of the severe acute respiratory syndrome (SARS-CoV-2). Viral ma
Externí odkaz:
https://doaj.org/article/989ba5b657e0463bb4b90c42dfdd77fb
Autor:
Luis Leyva-Parra, Diego Inostroza, Osvaldo Yañez, Julio César Cruz, Jorge Garza, Víctor García, William Tiznado
Publikováno v:
Atoms, Vol 10, Iss 1, p 27 (2022)
Recently, we reported a series of global minima whose structures consist of carbon rings decorated with heavier group 14 elements. Interestingly, these structures feature planar tetracoordinate carbons (ptCs) and result from the replacement of five o
Externí odkaz:
https://doaj.org/article/290d9395589e4eeb92185ff03385dd95