Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Osvaldo P de Melo Neto"'
Autor:
Ludmila A Assis, Moezio V C Santos Filho, Joao R da Cruz Silva, Maria J R Bezerra, Irassandra R P U C de Aquino, Kleison C Merlo, Fabiola B Holetz, Christian M Probst, Antonio M Rezende, Barbara Papadopoulou, Tamara D C da Costa Lima, Osvaldo P de Melo Neto
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009899 (2021)
Poly(A) Binding Proteins (PABPs) are major eukaryotic RNA-binding proteins (RBPs) with multiple roles associated with mRNA stability and translation and characterized mainly from multicellular organisms and yeasts. A variable number of PABP homologue
Externí odkaz:
https://doaj.org/article/7582158e93974ec7b0804d1be9beaee2
Autor:
Rhaíssa E M Ramos, Wagner J T Santos, Franklin B Magalhães, George T N Diniz, Carlos H N Costa, Osvaldo P de Melo Neto, Zulma M Medeiros, Christian R S Reis
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251861 (2021)
Visceral Leishmaniasis and HIV-AIDS coinfection (VL/HIV) is considered a life-threatening pathology when undiagnosed and untreated, due to the immunosuppression caused by both diseases. Serological tests largely used for the VL diagnosis include the
Externí odkaz:
https://doaj.org/article/65d9654ea7dd4c50a35bc4baeafc4d59
Autor:
Wagner J T Santos, Diego H C Tavares, Artur L Castro Neto, Marília B Nascimento, Rafael Dhalia, Alessandra L Albuquerque, Carlos H N Costa, Franklin B Magalhães, Antônio M Rezende, Osvaldo P de Melo Neto
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 7, p e0008488 (2020)
BackgroundVisceral leishmaniasis (VL) is a major neglected disease, potentially fatal, whose control is still impaired by inefficient and/or expensive treatment and diagnostic methods. The most promising approach for VL diagnosis uses serological ass
Externí odkaz:
https://doaj.org/article/23e52a803e854beaadd9cc3ce31f0c96
Autor:
Bruna S L Figueiredo de Sá, Antonio M Rezende, Osvaldo P de Melo Neto, Maria Edileuza F de Brito, Sinval P Brandão Filho
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 6, p e0007382 (2019)
Leishmania braziliensis, the main etiological agent of cutaneous leishmaniasis (CL) in Latin America, is characterized by major differences in basic biology in comparison with better-known Leishmania species. It is also associated with a high phenoty
Externí odkaz:
https://doaj.org/article/37bd11eb787e460789a403fdcbde7e57
Autor:
Franklin B Magalhães, Artur L Castro Neto, Marilia B Nascimento, Wagner J T Santos, Zulma M Medeiros, Adelino S Lima Neto, Dorcas L Costa, Carlos H N Costa, Washington L C Dos Santos, Lain C Pontes de Carvalho, Geraldo G S Oliveira, Osvaldo P de Melo Neto
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184867 (2017)
Current strategies for the control of zoonotic visceral leishmaniasis (VL) rely on its efficient diagnosis in both human and canine hosts. The most promising and cost effective approach is based on serologic assays with recombinant proteins. However,
Externí odkaz:
https://doaj.org/article/544226c170de459db0cdca9439dc982e
Autor:
Hiva Azizi, Tatiany P Romão, Karen Santos Charret, Prasad K Padmanabhan, Osvaldo P de Melo Neto, Michaela Müller-McNicoll, Barbara Papadopoulou
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180678 (2017)
We have reported previously that Short Interspersed Degenerate Retroposons of the SIDER2 subfamily, largely located within 3'UTRs of Leishmania transcripts, promote rapid turnover of mRNAs through endonucleolytic cleavage within the highly conserved
Externí odkaz:
https://doaj.org/article/92144055325c405e8346b7c456940097
Autor:
Renato Ferras Penteado, Renata Santana da Silva, Danielle Maria Nascimento Moura, Gustavo Barbosa de Lima, Amaranta Muniz Malvezzi, Tallyta Tâmara da Silva Monteiro, Camila Cavalcanti Xavier, Sophie Vichier-Guerre, Laurence Dugué, Sylvie Pochet, Nilson Ivo Tonin Zanchin, Christian Robson de Souza Reis, Osvaldo Pompílio de Melo Neto, Beatriz Gomes Guimarães
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Recognition of the mRNA 5′ end is a critical step needed for translation initiation. This step is performed by the cap binding protein eIF4E, which joins the larger eIF4G subunit to form the eIF4F complex. Trypanosomatids have a minimum of
Externí odkaz:
https://doaj.org/article/f7786e52a72f4a5ab2057eaf649e92ed
Autor:
Tatiana M. T. Rezende, Heverly S. G. Menezes, Antonio M. Rezende, Milena P. Cavalcanti, Yuri M. G. Silva, Osvaldo P. de-Melo-Neto, Tatiany P. Romão, Maria Helena N. L. Silva-Filha
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 33 (2023)
Culex quinquefasciatus resistance to the binary (Bin) toxin, the major larvicidal component from Lysinibacillus sphaericus, is associated with mutations in the cqm1 gene, encoding the Bin-toxin receptor. Downregulation of the cqm1 transcript was foun
Externí odkaz:
https://doaj.org/article/0ce161a7d4a84e199cb685d075b15011
Autor:
Nilma C. Leal, Túlio L. Campos, Antonio M. Rezende, Cássia Docena, Carina L. Mendes-Marques, Felipe L. de Sá Cavalcanti, Gabriel L. Wallau, Igor V. Rocha, Carmelita L. B. Cavalcanti, Dyana L. Veras, Lilian R. Alves, Mariana Andrade-Figueiredo, Maria P. Silva de Barros, Alzira M. Paiva de Almeida, Marcia M. Camargo de Morais, Tereza C. Leal-Balbino, Danilo E. Xavier, Osvaldo P. de-Melo-Neto
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Acinetobacter baumannii is an opportunistic bacterial pathogen infecting immunocompromised patients and has gained attention worldwide due to its increased antimicrobial resistance. Here, we report a comparative whole-genome sequencing and analysis c
Externí odkaz:
https://doaj.org/article/284197cf49244007a79c7a7f6056d87a
Autor:
Rafael de Freitas e Silva, Beatriz Coutinho de Oliveira, Ailton Alvaro da Silva, Maria Carolina Accioly Brelaz de Castro, Luiz Felipe Gomes Rebello Ferreira, Marcelo Zaldini Hernandes, Maria Edileuza Felinto de Brito, Osvaldo Pompílio de-Melo-Neto, Antônio Mauro Rezende, Valéria Rêgo Alves Pereira
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Background: A safe and effective vaccine against human leishmaniasis still requires the identification of better antigens for immunization and adequate models to evaluate the immune response. To support vaccine development, this work tested the immun
Externí odkaz:
https://doaj.org/article/839b768bcf44497d8cfd017d62dc449c