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Nucleolar RNA polymerase II drives ribosome biogenesis.

Autor: Abraham KJ; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Khosraviani N; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Chan JNY; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Gorthi A; Greehey Children's Cancer Research Institute, Department of Cell Systems and Anatomy, University of Texas Health at San Antonio, San Antonio, TX, USA., Samman A; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Zhao DY; Department of Molecular Genetics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada., Wang M; Sylvester Comprehensive Cancer Center, Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL, USA., Bokros M; Sylvester Comprehensive Cancer Center, Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL, USA., Vidya E; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Ostrowski LA; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Oshidari R; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Pietrobon V; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Patel PS; Princess Margaret Cancer Research Centre, University Health Network, and Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Algouneh A; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Princess Margaret Cancer Research Centre, University Health Network, and Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Singhania R; Princess Margaret Cancer Research Centre, University Health Network, and Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Liu Y; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Yerlici VT; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., De Carvalho DD; Princess Margaret Cancer Research Centre, University Health Network, and Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Ohh M; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Dickson BC; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada., Hakem R; Princess Margaret Cancer Research Centre, University Health Network, and Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Greenblatt JF; Department of Molecular Genetics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada., Lee S; Sylvester Comprehensive Cancer Center, Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL, USA., Bishop AJR; Greehey Children's Cancer Research Institute, Department of Cell Systems and Anatomy, University of Texas Health at San Antonio, San Antonio, TX, USA.; Mays Cancer Center, University of Texas Health at San Antonio, San Antonio, TX, USA., Mekhail K; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. karim.mekhail@utoronto.ca.; Canada Research Chairs Program, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. karim.mekhail@utoronto.ca.

Publikováno v: Nature [Nature] 2020 Sep; Vol. 585 (7824), pp. 298-302. Date of Electronic Publication: 2020 Jul 15.

Phase Separation as a Melting Pot for DNA Repeats.

Autor: Hall AC; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, 661 University Avenue, Toronto, ONT, M5G 1M1, Canada., Ostrowski LA; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, 661 University Avenue, Toronto, ONT, M5G 1M1, Canada., Mekhail K; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, 661 University Avenue, Toronto, ONT, M5G 1M1, Canada; Canada Research Chairs Program, Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, ONT, M5S 1A8, Canada. Electronic address: karim.mekhail@utoronto.ca.

Publikováno v: Trends in genetics : TIG [Trends Genet] 2019 Aug; Vol. 35 (8), pp. 589-600. Date of Electronic Publication: 2019 May 31.

Investigating Teliospore Germination Using Microrespiration Analysis and Microdissection.

Autor: Ostrowski LA; Environmental and Life Sciences Graduate Department, Trent University., Seto AM; Environmental and Life Sciences Graduate Department, Trent University., Saville B; Environmental and Life Sciences Graduate Department, Trent University; Forensic Science Department, Trent University; barrysaville@trentu.ca.

Publikováno v: Journal of visualized experiments : JoVE [J Vis Exp] 2018 May 13 (135). Date of Electronic Publication: 2018 May 13.

Functional Amyloids and their Possible Influence on Alzheimer Disease.

Autor: Lau A; Department of Laboratory Medicine & Pathobiology, University of Toronto, Medical Sciences Building, 6th Floor, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada.; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Krembil Discovery Centre, 6th Floor, 60 Leonard Avenue, Toronto, Ontario M5T 2S8, Canada., Bourkas M; Department of Laboratory Medicine & Pathobiology, University of Toronto, Medical Sciences Building, 6th Floor, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada.; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Krembil Discovery Centre, 6th Floor, 60 Leonard Avenue, Toronto, Ontario M5T 2S8, Canada., Lu YQQ; Department of Laboratory Medicine & Pathobiology, University of Toronto, Medical Sciences Building, 6th Floor, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada., Ostrowski LA; Department of Laboratory Medicine & Pathobiology, University of Toronto, Medical Sciences Building, 6th Floor, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada., Weber-Adrian D; Department of Laboratory Medicine & Pathobiology, University of Toronto, Medical Sciences Building, 6th Floor, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada., Figueiredo C; Department of Laboratory Medicine & Pathobiology, University of Toronto, Medical Sciences Building, 6th Floor, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada., Arshad H; Department of Laboratory Medicine & Pathobiology, University of Toronto, Medical Sciences Building, 6th Floor, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada.; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Krembil Discovery Centre, 6th Floor, 60 Leonard Avenue, Toronto, Ontario M5T 2S8, Canada., Shoaei SZS; Department of Laboratory Medicine & Pathobiology, University of Toronto, Medical Sciences Building, 6th Floor, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada., Morrone CD; Department of Laboratory Medicine & Pathobiology, University of Toronto, Medical Sciences Building, 6th Floor, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada., Matan-Lithwick S; Department of Laboratory Medicine & Pathobiology, University of Toronto, Medical Sciences Building, 6th Floor, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada., Abraham KJ; Department of Laboratory Medicine & Pathobiology, University of Toronto, Medical Sciences Building, 6th Floor, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada., Wang H; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Krembil Discovery Centre, 6th Floor, 60 Leonard Avenue, Toronto, Ontario M5T 2S8, Canada., Schmitt-Ulms G; Department of Laboratory Medicine & Pathobiology, University of Toronto, Medical Sciences Building, 6th Floor, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada.; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Krembil Discovery Centre, 6th Floor, 60 Leonard Avenue, Toronto, Ontario M5T 2S8, Canada.

Publikováno v: Discoveries (Craiova, Romania) [Discoveries (Craiova)] 2017 Oct 16; Vol. 5 (4), pp. e79. Date of Electronic Publication: 2017 Oct 16.