Impact of type III receptor tyrosine kinases on viability, proliferation, metabolism and therapy-sensitivity of stem-like glioma cells

Autor: Boldt, LM, Lueg, T, Willeke, V, Elssner, J, Ostermaier, JJ, Däumer, F, Tronnier, VM, Zechel, C

Publikováno v: 71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie; 20200621-20200624; sine loco [digital]; DOCV275 /20200626/

Objective: The glioblastoma multiforme (GBM) and the gliosarcoma (GSarc) are primary brain tumors with a high morbidity and mortality, offering only palliation. Stem-like glioma cells (SLGCs) are considered as one major cause of treatment failure and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc7dced5b6f3f178a4e71caf541d53c

Molecular signature of stem-like glioma cells (SLGCs) from human glioblastoma and gliosarcoma.

Autor: Zechel C; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Lübeck, Germany.; Department of Neurosurgery, University Clinic Schleswig-Holstein, Campus Lübeck, Lübeck, Germany., Loy M; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Lübeck, Germany., Wegner C; Institute for Neuro- and Bioinformatics (INB), University Lübeck, Lübeck, Germany., Dahlke E; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Lübeck, Germany., Soetje B; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Lübeck, Germany., Baehr L; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Lübeck, Germany., Leppert J; Department of Neurosurgery, University Clinic Schleswig-Holstein, Campus Lübeck, Lübeck, Germany., Ostermaier JJ; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Lübeck, Germany., Lueg T; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Lübeck, Germany., Nielsen J; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Lübeck, Germany., Elßner J; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Lübeck, Germany., Willeke V; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Lübeck, Germany., Marzahl S; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Lübeck, Germany., Tronnier V; Department of Neurosurgery, University Clinic Schleswig-Holstein, Campus Lübeck, Lübeck, Germany., Madany Mamlouk A; Institute for Neuro- and Bioinformatics (INB), University Lübeck, Lübeck, Germany.

Publikováno v: PloS one [PLoS One] 2024 Feb 02; Vol. 19 (2), pp. e0291368. Date of Electronic Publication: 2024 Feb 02 (Print Publication: 2024).