Insufficient insulin administration to diabetic rats increases substrate utilization and maintains lactate production in the kidney.

Autor: Laustsen C; Department of Clinical Medicine, MR Research Centre, Aarhus University, Aarhus, Denmark., Lipsø K; Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark Department of Electrical Engineering, Technical University of Denmark, Kgs. Lyngby, Denmark., Ostergaard JA; Department of Endocrinology and Internal Medicine and Danish Diabetes Academy, Aarhus University Hospital, Aarhus, Denmark Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark., Nørregaard R; Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark., Flyvbjerg A; Department of Endocrinology and Internal Medicine and Danish Diabetes Academy, Aarhus University Hospital, Aarhus, Denmark Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark., Pedersen M; Department of Clinical Medicine, MR Research Centre, Aarhus University, Aarhus, Denmark Comparative Medicine Lab, Aarhus University, Aarhus, Denmark., Palm F; Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden Division of Drug Research, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden Center for Medical Image Science and Visualization, Linköping University, Linköping, Sweden., Ardenkjær-Larsen JH; Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark Department of Electrical Engineering, Technical University of Denmark, Kgs. Lyngby, Denmark GE Healthcare, Broendby, Denmark.

Publikováno v: Physiological reports [Physiol Rep] 2014 Dec 11; Vol. 2 (12). Date of Electronic Publication: 2014 Dec 11 (Print Publication: 2014).

Comment on: Lin et al. (2010) Immune cell-derived C3 is required for autoimmune diabetes induced by multiple low doses of streptozotocin. Diabetes;59: 2247-2252.

Autor: Ostergaard JA, Thiel S, Hansen TK, Rasch R, Flyvbjerg A

Publikováno v: Diabetes [Diabetes] 2011 Jan; Vol. 60 (1), pp. e7-8; author reply e9.