Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Osteogenesis / drug effects"'
Autor:
Elizabeth R. Balmayor, Carlos J Peniche Silva, Manish K. Aneja, Christian Plank, Christopher H. Evans, Martijn van Griensven, Sebastian A Müller, Michael J. Coenen, Rodolfo E. De la Vega, Wen Zhang
Publikováno v:
Tissue Engineering. Part A, 25(1-2), 131-144. Mary Ann Liebert Inc.
The first therapeutic application of messenger RNA (mRNA) was suggested more than two decades ago. However, its application was constrained by the ability of mRNA to activate the innate immune response, cytotoxicity, and poor potency. We and others r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b8b4dbefa5bac75702e829a494bc86
https://doi.org/10.1089/ten.tea.2018.0112
https://doi.org/10.1089/ten.tea.2018.0112
Autor:
Karsten Skjødt, Moustapha Kassem, Charlotte Harken Jensen, Søren P. Sheikh, Nicholas Ditzel, Florence Figeac, Casper A. Nipper Nielsen, Basem M. Abdallah, Ditte Caroline Andersen
Publikováno v:
Figeac, F, Andersen, D C, Nipper Nielsen, C A, Ditzel, N, Sheikh, S P, Skjødt, K, Kassem, M, Jensen, C H & Abdallah, B M 2018, ' Antibody-based inhibition of circulating DLK1 protects from estrogen deficiency-induced bone loss in mice ', Bone, vol. 110, pp. 312-320 . https://doi.org/10.1016/j.bone.2018.02.030
Soluble delta-like 1 homolog (DLK1) is a circulating protein that belongs to the Notch/Serrate/delta family, which regulates many differentiation processes including osteogenesis and adipogenesis. We have previously demonstrated an inhibitory effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3754b76f7cc73551cea316d4fda0e1
https://doi.org/10.1016/j.bone.2018.02.030
https://doi.org/10.1016/j.bone.2018.02.030
Autor:
Frédéric Baron, Arnold Bolomsky, Elodie Duray, Jo Caers, Roy Heusschen, Joséphine Muller, Heinz Ludwig, Yves Beguin, Nadia Withofs, Eline Menu
Publikováno v:
Leukemia & Lymphoma. 59:14-28
Multiple myeloma (MM) bone disease is a major cause of morbidity and mortality in MM patients and persists even in patients in remission. This bone disease is caused by an uncoupling of bone remodeling, with increased osteoclast and decreased osteobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::183515d0fc0c6aa5876c01201607f1c2
https://doi.org/10.1080/10428194.2017.1323272
https://doi.org/10.1080/10428194.2017.1323272
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 11(4):1122-1131
Synthetic graft materials are considered as possible substitutes for cancellous bone, but lack osteogenic and osteoinductive properties. In this study, we investigated how composite scaffolds of βTCP containing osteogenic human bone marrow mesenchym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od________83::d5e767bff007a7089471f92d5d0bbc0d
https://cris.maastrichtuniversity.nl/en/publications/8d76bbf5-a1cd-4b10-b05e-532c727e38b8
https://cris.maastrichtuniversity.nl/en/publications/8d76bbf5-a1cd-4b10-b05e-532c727e38b8
Autor:
Rubens Spin-Neto, Andreas Stavropoulos, Guilherme José Pimentel Lopes de Oliveira, Cássio Rocha Scardueli, Fernanda Castanheira Gonçalves, Rosemary Adriana Chierici Marcantonio
Publikováno v:
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Brazilian Oral Research, Vol 34 (2020)
Gonçalves, F C, Oliveira, G J P L D, Scardueli, C R, Spin-Neto, R, Stavropoulos, A & Marcantonio, R A C 2020, ' Cyclosporine A impairs bone repair in critical defects filled with different osteoconductive bone substitutes ', Brazilian Oral Research, vol. 34, e007 . https://doi.org/10.1590/1807-3107bor-2020.vol34.0007
Brazilian Oral Research, Volume: 34, Article number: e007, Published: 07 FEB 2020
Brazilian Oral Research v.34 2020
Brazilian Oral Research
Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron:SBPQO
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Brazilian Oral Research, Vol 34 (2020)
Gonçalves, F C, Oliveira, G J P L D, Scardueli, C R, Spin-Neto, R, Stavropoulos, A & Marcantonio, R A C 2020, ' Cyclosporine A impairs bone repair in critical defects filled with different osteoconductive bone substitutes ', Brazilian Oral Research, vol. 34, e007 . https://doi.org/10.1590/1807-3107bor-2020.vol34.0007
Brazilian Oral Research, Volume: 34, Article number: e007, Published: 07 FEB 2020
Brazilian Oral Research v.34 2020
Brazilian Oral Research
Sociedade Brasileira de Pesquisa Odontológica (SBPqO)
instacron:SBPQO
Made available in DSpace on 2020-12-12T01:56:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01 The aim of this study was to assess the influence of cyclosporine administration on the repair of critical-sized calvaria defects (CSDs) in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feaedec429a845e28c57cb3ba4c7559b
Autor:
Anja Seckinger, Giorgio Mori, Volker Martin, Anna Luise Grab, Elisabetta Ada Cavalcanti-Adam, Slobodan Vukicevic, Francesca Posa, Dirk Hose
Publikováno v:
Cells
Volume 8
Issue 12
Volume 8
Issue 12
We report on the covalent immobilization of bone morphogenetic protein 6 (BMP-6) and its co-presentation with integrin ligands on a nanopatterned platform to study cell adhesion and signaling responses which regulate the transdifferentiation of myobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::585faf31fe1d433826775658439c7746
Publikováno v:
Sølling, A S K, Harsløf, T & Langdahl, B 2019, ' Current Status of Bone-Forming Therapies for the Management of Osteoporosis ', Drugs & Aging, vol. 36, no. 7, pp. 625-638 . https://doi.org/10.1007/s40266-019-00675-8
In patients with osteoporosis and severely reduced bone mass and/or recurring fractures, antiresorptive therapy may not be the optimal first-line treatment. Two recent clinical trials comparing bone-forming treatment with antiresorptive therapy have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1519fe9d6301952282d1f883e8e9f492
https://pubmed.ncbi.nlm.nih.gov/31066015
https://pubmed.ncbi.nlm.nih.gov/31066015
Autor:
Christian Koch, Christian Plank, Carsten Rudolph, Elizabeth R. Balmayor, Martijn van Griensven, Johannes Geiger, Manish K. Aneja
Publikováno v:
Stem Cells and Development, 26(1), 25-34. Mary Ann Liebert Inc.
Bone regeneration using stem cells and growth factors has disadvantages while needing to use supraphysiological growth factors concentrations. Gene therapy has been proposed as alternative, but also has limitation. Messenger RNA (mRNA)-based transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b99fee874a31717442ee1a3d0d1cb9
https://doi.org/10.1089/scd.2016.0171
https://doi.org/10.1089/scd.2016.0171
Publikováno v:
Acta Biomaterialia
Multiple myeloma is a malignant disease characterized by accumulation of clonal plasma cells in the bone marrow. Uncoupling of bone formation and resorption by myeloma cells leads to osteolytic lesions. These are prone to fracture and represent a pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e16eb0c25a47a13380ebb950f4647e07
https://doi.org/10.2139/ssrn.3368806
https://doi.org/10.2139/ssrn.3368806
Autor:
Sabine Schluessel, Andreas Fottner, Paul J. Kostenuik, Julia I. Redeker, Marina Unger, Martijn van Griensven, Jan Michael, Susanne Mayer-Wagner, Rene Beutner, Eliza S. Hartmann, Baerbel Schmitt, Miriam I. Koehler, Dieter Scharnweber, Burkhard Summer, Karl-Heinz Kunzelmann, Felicitas Beck
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 5
International Journal of Molecular Sciences, Vol 20, Iss 5, p 1002 (2019)
International journal of molecular sciences, 20(5):1002. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 20
Issue 5
International Journal of Molecular Sciences, Vol 20, Iss 5, p 1002 (2019)
International journal of molecular sciences, 20(5):1002. Multidisciplinary Digital Publishing Institute (MDPI)
Immobilization of proteins has been examined to improve implant surfaces. In this study, titanium surfaces were modified with nanofunctionalized denosumab (cDMAB), a human monoclonal anti-RANKL IgG. Noncoding DNA oligonucleotides (ODN) served as link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee58e8738d71feb31e8b23f8c037a5c
https://mediatum.ub.tum.de/doc/1546329/document.pdf
https://mediatum.ub.tum.de/doc/1546329/document.pdf