Inhibition of Notch Signaling Stimulates Osteoclastogenesis From the Common Trilineage Progenitor Under Inflammatory Conditions

Autor: Maša Filipović, Darja Flegar, Alan Šućur, Dino Šisl, Inga Kavazović, Mariastefania Antica, Tomislav Kelava, Nataša Kovačić, Danka Grčević

Publikováno v: Frontiers in Immunology
Volume 13

Osteoclasts, macrophages and dendritic cells (DCs) can be derived from a common trilineage myeloid progenitor of hematopoietic origin. Progenitor commitment is susceptible to regulation through Notch signaling. Our aim was to determine the effects of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32b1c4e57a79a2564e954062a80111e
https://repository.medri.uniri.hr/islandora/object/medri:6735/datastream/FILE0

Osteoclast Fusion: Time‐Lapse Reveals Involvement of CD47 and Syncytin‐1 at Different Stages of Nuclearity

Autor: Marie Julie Møller, Anaïs, Delaissé, Jean-Marie, Søe, Kent

Publikováno v: Journal of Cellular Physiology
Marie Julie Møller, A, Delaissé, J-M & Søe, K 2017, ' Osteoclast Fusion : Time-Lapse Reveals Involvement of CD47 and Syncytin-1 at Different Stages of Nuclearity ', Journal of Cellular Physiology, vol. 232, no. 6, pp. 1396-1403 . https://doi.org/10.1002/jcp.25633

Investigations addressing the molecular keys of osteoclast fusion are primarily based on end-point analyses. No matter if investigations are performed in vivo or in vitro the impact of a given factor is predominantly analyzed by counting the number o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9dda2fbc191ad880cf41549b9cebd316
http://europepmc.org/articles/PMC6221100

Co-Culture with Human Osteoblasts and Exposure to Extremely Low Frequency Pulsed Electromagnetic Fields Improve Osteogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells

Publikováno v: International journal of molecular sciences. 19(4)

Human adipose-derived mesenchymal stem cells (Ad-MSCs) have been proposed as suitable option for cell-based therapies to support bone regeneration. In the bone environment, Ad-MSCs will receive stimuli from resident cells that may favor their osteoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___00893::94e1845b5e615dd4031610acdbf17f5e
https://doi.org/10.3390/ijms19040994

The transient receptor potential channel TRPV6 is dynamically expressed in bone cells but is not crucial for bone mineralization in mice

Autor: Marc Freichel, Petra Weissgerber, Johannes P.T.M. van Leeuwen, Veit Flockerzi, Klaus Klaushofer, Paul Roschger, Marijke Schreuders-Koedam, René J. M. Bindels, Marco Eijken, Nadja Fratzl-Zelman, Joost G. J. Hoenderop, Teun J. de Vries, Jenny Olausson, Bram C. J. van der Eerden, Hideki Chiba

Publikováno v: Journal of Cellular Physiology, 227, 5, pp. 1951-9
Journal of Cellular Physiology, 227(5), 1951-1959. Wiley-Liss Inc.
van der Eerden, B C J, Weissgerber, P, Fratzl-Zelman, N, Olausson, J, Hoenderop, J G J, Schreuders-Koedam, M, Eijken, M, Roschger, P, de Vries, T J, Chiba, H, Klaushofer, K, Flockerzi, V, Bindels, R J M, Freichel, M & van Leeuwen, J P T M 2012, ' The transient receptor potential channel TRPV6 is dynamically expressed in bone cells but is not crucial for bone mineralization in mice ', Journal of Cellular Physiology, vol. 227, no. 5, pp. 1951-9 . https://doi.org/10.1002/jcp.22923
van der Eerden, B C J, Weissgerber, P, Fratzl-Zelman, N, Olausson, J, Hoenderop, J G J, Schreuders-Koedam, M, Eijken, M, Roschger, P, de Vries, T J, Chiba, H, Klaushofer, K, Flockerzi, V, Bindels, R J M, Freichel, M & van Leeuwen, J P T M 2012, ' The transient receptor potential channel TRPV6 is dynamically expressed in bone cells but is not crucial for bone mineralization in mice ', Journal of Cellular Physiology, vol. 227, no. 5, pp. 1951-1959 . https://doi.org/10.1002/jcp.22923
Journal of Cellular Physiology, 227, 1951-9

Item does not contain fulltext Bone is the major store for Ca(2+) in the body and plays an important role in Ca(2+) homeostasis. During bone formation and resorption Ca(2+) must be transported to and from bone by osteoblasts and osteoclasts, respecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5163b0856b736a07368f4d6179ee5792
https://hdl.handle.net/2066/109949