Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Osteoblastic lesions"'
Autor:
Fanchun Zeng, Chunrong Zhao, Rujie Wang, Lingyan Ren, Hao Qiu, Zhi Zou, Haibin Ding, Zhongyi Sun, Jianmei Li, Shiwu Dong
Publikováno v:
Genes and Diseases, Vol 10, Iss 4, Pp 1626-1640 (2023)
More than 50% of prostate cancer (PCa) patients have bone metastasis with osteoblastic lesions. MiR-18a-5p is associated with the development and metastasis of PCa, but it remains unclear whether it is involved in osteoblastic lesions. We first found
Externí odkaz:
https://doaj.org/article/90276746e6aa4ac0903f66ad2543dea4
Akademický článek
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Autor:
O. Annibali, M.T. Petrucci, D. Santini, V. Bongarzoni, M. Russano, F. Pisani, O. Venditti, F. Pantano, A. Rago, A. Siniscalchi, E. Cerchiara, L. Franceschini, L. De Rosa, M. Mariani, S Andriani, L. Cudillo, M. Garcia, M. Cantonetti, S. Mohamed, B. Anaclerico, T. Caravita, F. Stocchi, G. Cimino, S. Gumenyuk, F. Vozella, G. Avvisati
Publikováno v:
Journal of Bone Oncology, Vol 26, Iss , Pp 100338- (2021)
Introduction: Bone involvement in Multiple Myeloma results from increased osteoclast formation and activity that occurs in proximity to myeloma cells. The role of Alkaline Phosphatse (ALP) in this process and the diagnostic significance of plasma lev
Externí odkaz:
https://doaj.org/article/8841fd0890204e22a2c39a92f4d2d0cc
Publikováno v:
Cells, Vol 11, Iss 8, p 1309 (2022)
Metastatic bone disease is a common and devastating complication to cancer, confounding treatments and recovery efforts and presenting a significant barrier to de-escalating the adverse outcomes associated with disease progression. Despite significan
Externí odkaz:
https://doaj.org/article/42b25d0c60f3451bb4192e0a9a61bfcb
Akademický článek
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Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 10; Pages: 2850
Metastatic lesions compromise the mechanical integrity of vertebrae, increasing the fracture risk. Screw fixation is usually performed to guarantee spinal stability and prevent dramatic fracture events. Accordingly, predicting the overall mechanical
Autor:
Mariana Quiroz-Munoz, Beatrice Wong, Alexander Kirschenbaum, Alice C. Levine, Dushyanthy Arumugam, Sudeh Izadmehr
Publikováno v:
Journal of the Endocrine Society
Prostate cancer (PCa) preferentially metastasizes to bone, leading to complications including severe pain, fractures, spinal cord compression, bone marrow suppression, and a mortality of ∼70%. In spite of recent advances in chemo-, hormonal, and ra
Akademický článek
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Autor:
S. Mohamed, F. Stocchi, Ombretta Annibali, Barbara Anaclerico, Svitlana Gumenyuk, Agostina Siniscalchi, Luca Franceschini, Velia Bongarzoni, Maria Cantonetti, Giuseppe Avvisati, Angela Rago, L. Cudillo, Tommaso Caravita, Federico Vozella, O. Venditti, Marco Russano, María de las Olas Palma García, Giuseppe Cimino, E. Cerchiara, Francesco Pisani, Daniele Santini, L. De Rosa, Marco Mariani, M.T. Petrucci, Francesco Pantano, S Andriani
Publikováno v:
Journal of Bone Oncology
Journal of Bone Oncology, Vol 26, Iss, Pp 100338-(2021)
Journal of Bone Oncology, Vol 26, Iss, Pp 100338-(2021)
Highlights • Plasma ALP could be used as a discriminating marker in presence of bone lesions in solid tumor or MM. • Multiple Myeloma, ALP values were mainly in the range of normality than those observed in patients with solid cancers and bone le
Autor:
Rachel Deplus, Martine Duterque-Coquillaud, Anne Flourens, Edith Bonnelye, Nathalie Vanpouille, Tian V. Tian, Philippe Clézardin, Anais Fradet, Carine Delliaux, Xavier Leroy, Yvan de Launoit, Mathilde Bouchet, Arnauld Villers
Publikováno v:
Cancer Letters
Cancer Letters, Elsevier, 2018, 438, pp.32-43. ⟨10.1016/j.canlet.2018.08.027⟩
Cancer Letters, 2018, 438, pp.32-43. ⟨10.1016/j.canlet.2018.08.027⟩
Cancer Letters, Elsevier, 2018, 438, pp.32-43. ⟨10.1016/j.canlet.2018.08.027⟩
Cancer Letters, 2018, 438, pp.32-43. ⟨10.1016/j.canlet.2018.08.027⟩
International audience; Abstract : Prostate cancers have a strong propensity to metastasize to bone and promote osteoblastic lesions. TMPRSS2:ERG is the most frequent gene rearrangement identified in prostate cancer, but whether it is involved in pro