Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ossie F Dyson"'
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33364 (2012)
In the field of herpesvirus research, the exact molecular mechanism by which such viruses reactivate from latency remains elusive. Kaposi's sarcoma-associated herpesvirus (KSHV) primarily exists in a latent state, while only 1-3% of cells support lyt
Externí odkaz:
https://doaj.org/article/6bf2d48d05de4466b6a8bf120b0b5eb0
Publikováno v:
Journal of Virology. 91
Epstein-Barr virus (EBV) infection and lytic replication are known to induce a cellular DNA damage response. We previously showed that the virally encoded BPLF1 protein interacts with and regulates several members of the translesion synthesis (TLS) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c04a2bd63519483a2a5c9a5ed51f0e0
https://doi.org/10.1128/jvi.00600-17
https://doi.org/10.1128/jvi.00600-17
Autor:
Shaw M. Akula, John F. Williams, Sergio Arce, Ossie F. Dyson, Hersh Patel, Wylder Fondaw, Lia R. Walker, Sheran Mahatme, Christopher M. Traylen
Publikováno v:
Future Virology. 6:451-463
Viruses are obligate intracellular parasites, relying to a major extent on the host cell for replication. An active replication of the viral genome results in a lytic infection characterized by the release of new progeny virus particles, often upon t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d500d607b9d1cbabd189b8f3f2943f1c
https://doi.org/10.2217/fvl.11.21
https://doi.org/10.2217/fvl.11.21
Publikováno v:
Journal of Biological Chemistry. 285:37491-37502
One of the important questions in the field of virus research is about the balance between latent and lytic cycles of replication. Kaposi's sarcoma-associated herpesvirus (KSHV) remains predominantly in a latent state, with only 1–3% of cells suppo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1731cdedfce53f37e80ec234d65ee114
https://doi.org/10.1074/jbc.m110.159103
https://doi.org/10.1074/jbc.m110.159103
Publikováno v:
Journal of Cellular and Molecular Medicine
Kaposi's sarcoma-associated herpesvirus (KSHV) has both latent and lytic phases of replication. The molecular switch that triggers a reactivation is still unclear. Cells from S phase of cell cycle provide apt conditions for an active reactivation. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3325440677342922319d6e23f7e0c7e3
http://europepmc.org/articles/PMC2819606
http://europepmc.org/articles/PMC2819606
Publikováno v:
Cellular Microbiology. 10:1546-1558
Kaposi's sarcoma-associated herpesvirus (KSHV) has two modes of replications: latent and lytic replications. Reactivation from latency is dictated, in part, by the cell cycle. Herein, we have attempted to delineate the importance of cell cycle in KSH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23793bd98480ac9d1ca9b2ba321dac41
https://doi.org/10.1111/j.1462-5822.2008.01149.x
https://doi.org/10.1111/j.1462-5822.2008.01149.x
Autor:
Adrian J. Reber, Ossie F. Dyson, Audy G. Whitman, Shaw M. Akula, Aniqa Z Shahrier, James A. McCubrey, Phelps J. Lambert
Publikováno v:
Expert Opinion on Therapeutic Targets. 11:589-599
Cells require the ability to appropriately respond to signals in their extracellular environment. To initiate, inhibit and control these processes, the cell has developed a complex network of signaling cascades. The phosphatidylinositol 3-kinase (PI3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332580449983fc4c5511b610b6523261
https://doi.org/10.1517/14728222.11.5.589
https://doi.org/10.1517/14728222.11.5.589
Publikováno v:
Intervirology. 50:245-253
Objective: Angiogenesis is defined as the formation of new blood vessels. In a recently concluded study, we identified Kaposi’s sarcoma-associated herpesvirus (KSHV)-infected cells derived from primary effusion lymphoma (PEL) to overexpress vascula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70fb261b48bdf6880fdd2900d718d34e
https://doi.org/10.1159/000101995
https://doi.org/10.1159/000101995
Autor:
Patrick W. Ford, Benjaman A. Bryan, Shaw M. Akula, Douglas A. Weidner, Vishnu Chintalgattu, Ossie F. Dyson
Publikováno v:
Journal of General Virology. 87:1139-1144
Kaposi's sarcoma-associated herpesvirus (KSHV) causes Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease. KSHV infection of cells produces both latent and lytic cycles of infection. In vivo, the virus is found predominan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::571344fd7291de336b8b860d1b21727e
https://doi.org/10.1099/vir.0.81628-0
https://doi.org/10.1099/vir.0.81628-0
Publikováno v:
Journal of General Virology. 87:519-529
Kaposi's sarcoma-associated herpesvirus (KSHV) is the latest addition to the long list of human herpesviruses. Reactivation of latent herpesvirus infections is still a mystery. It was demonstrated recently that the phorbol ester TPA was efficient in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7101024a6418fda6bdff8001d80cdbaa
https://doi.org/10.1099/vir.0.81603-0
https://doi.org/10.1099/vir.0.81603-0