Data from Chemosensitization by Knockdown of Adenine Nucleotide Translocase-2

Autor: Catherine Brenner, Etienne Jacotot, Guido Kroemer, Christophe Lemaire, Dominique Rebouillat, Gael Lecellier, Evelyne Maillier, Aurélien Deniaud, Ossama Sharaf El Dein, Zahia Touat, Annie Borgne-Sanchez, Morgane Le Bras

Mitochondrial membrane permeabilization (MMP) is a rate-limiting step of apoptosis, including in anticancer chemotherapy. Adenine nucleotide translocase (ANT) mediates the exchange of ADP and ATP on the inner mitochondrial membrane in healthy cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8560311be7ed3ccf231cad4e1c5f0334
https://doi.org/10.1158/0008-5472.c.6494123

Involvement of mitochondria-mediated apoptosis in deoxynivalenol cytotoxicity

Autor: Mohamed Rabeh Hajlaoui, Hassen Bacha, Christophe Lemaire, Cindy Gallerne, Fatma Bensassi, Ossama Sharaf el dein

Publikováno v: Food and Chemical Toxicology. 50:1680-1689

Deoxynivalenol (DON) is a widespread trichothecene mycotoxin which contaminates cereal crops and harmfully affects the gastrointestinal tract. Since it is well known that mitochondria play a central role in apoptosis triggered by many stimuli, an eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44eae8aba5ce820b44e65db3bbf2190
https://doi.org/10.1016/j.fct.2012.01.015

The fourth isoform of the adenine nucleotide translocator inhibits mitochondrial apoptosis in cancer cells

Autor: Cécile Martel, Morgane Le Bras, Etienne Jacotot, Christophe Lemaire, Zahia Touat, Shazib Pervaiz, Zhi Xiong Chen, Annie Borgne-Sanchez, Nelly Buron, Antoinette Lemoine, Cindy Gallerne, Catherine Brenner, Eleonore Mayola, Ossama Sharaf el dein

Publikováno v: The International Journal of Biochemistry & Cell Biology. 42:623-629

The adenine nucleotide translocator (ANT) is a mitochondrial bi-functional protein, which catalyzes the exchange of ADP and ATP between cytosol and mitochondria and participates in many models of mitochondrial apoptosis. The human adenine nucleotide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afefef4c65edced14bba6f8b649182ec
https://doi.org/10.1016/j.biocel.2009.12.024

Combined effects of alternariols mixture on human colon carcinoma cells

Autor: Christophe Lemaire, Cindy Gallerne, Hassen Bacha, Mohamed Rabeh Hajlaoui, Ossama Sharaf el dein, Fatma Bensassi

Publikováno v: Toxicology mechanisms and methods. 25(1)

Mycotoxins are naturally occurring contaminants encountered at high levels in a wide variety of agricultural products intended for human and animal consumptions. Various Alternaria mycotoxins may occur simultaneously in small grain cereals. Consideri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b852107ee3af24ad242ffdf4a9a21dd
https://pubmed.ncbi.nlm.nih.gov/25496143

ANT-VDAC1 interaction is direct and depends on ANT isoform conformation in vitro

Autor: Céline Henry, Maya Allouche, Cécile Martel, Ossama Sharaf el dein, Nathalie Saint, Catherine Brenner, Joël Chopineau, Jean-Luc Robert, Claire Pertuiset, Remi Veneziano

Publikováno v: Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, Elsevier, 2012, 429 (1-2), pp.12-7. ⟨10.1016/j.bbrc.2012.10.108⟩

International audience; The voltage-dependent anion channel (VDAC) and the adenine nucleotide translocase (ANT) have central roles in mitochondrial functions such as nucleotides transport and cell death. The interaction between VDAC, an outer mitocho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f169dbedc15b57f254a1177985410a3f
https://hal.archives-ouvertes.fr/hal-00828068