Benzothiazole Substitution Analogs of Rhodacyanine Hsp70 Inhibitors Modulate Tau Accumulation .

Autor: Hill SE; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, Florida 33612, United States., Beaulieu-Abdelahad D; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, Florida 33612, United States., Lemus A; Department of Chemistry, University of South Florida, 4202 East Fowler Avenue, CHE 205, Tampa, Florida 33620, United States., Webster JM; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, Florida 33612, United States., Ospina SR; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, Florida 33612, United States., Darling AL; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, Florida 33612, United States., Martin MD; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, Florida 33612, United States., Patel S; Department of Chemistry, University of South Florida, 4202 East Fowler Avenue, CHE 205, Tampa, Florida 33620, United States., Bridenstine L; Department of Chemistry, University of South Florida, 4202 East Fowler Avenue, CHE 205, Tampa, Florida 33620, United States., Swonger R; Department of Chemistry, University of South Florida, 4202 East Fowler Avenue, CHE 205, Tampa, Florida 33620, United States., Paul S; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, Florida 33612, United States., Blackburn R; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, Florida 33612, United States., Calcul L; Department of Chemistry, University of South Florida, 4202 East Fowler Avenue, CHE 205, Tampa, Florida 33620, United States., Dickey CA; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, Florida 33612, United States.; Research Service, James A Haley Veterans Hospital, 13000 Bruce B Downs Blvd, Tampa, Florida 33612, United States., Leahy JW; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.; Department of Chemistry, University of South Florida, 4202 East Fowler Avenue, CHE 205, Tampa, Florida 33620, United States.; Center for Drug Discovery and Innovation, University of South Florida, 3720 Spectrum Boulevard, Suite 303, Tampa, Florida 33612, United States., Blair LJ; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida 33612, United States.; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, Florida 33612, United States.; Research Service, James A Haley Veterans Hospital, 13000 Bruce B Downs Blvd, Tampa, Florida 33612, United States.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2023 May 19; Vol. 18 (5), pp. 1124-1135. Date of Electronic Publication: 2023 May 05.

Structural and Mechanistic Analysis of Drosophila melanogaster Agmatine N-Acetyltransferase, an Enzyme that Catalyzes the Formation of N-Acetylagmatine.

Autor: Dempsey DR; Department of Chemistry, University of South Florida, Tampa, Florida, 33620, United States.; Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA., Nichols DA; Department of Molecular Medicine, University of South Florida, Tampa, Florida, 33612, United States.; Moffitt Cancer Center, Tampa, FL, 33612, United States., Battistini MR; Department of Chemistry, University of South Florida, Tampa, Florida, 33620, United States., Pemberton O; Department of Molecular Medicine, University of South Florida, Tampa, Florida, 33612, United States., Ospina SR; Department of Chemistry, University of South Florida, Tampa, Florida, 33620, United States., Zhang X; Department of Molecular Medicine, University of South Florida, Tampa, Florida, 33612, United States., Carpenter AM; Department of Chemistry, University of South Florida, Tampa, Florida, 33620, United States.; University of Florida, College of Medicine, Gainesville, FL, 32610-0216, United States., O'Flynn BG; Department of Chemistry, University of South Florida, Tampa, Florida, 33620, United States., Leahy JW; Department of Chemistry, University of South Florida, Tampa, Florida, 33620, United States.; Department of Molecular Medicine, University of South Florida, Tampa, Florida, 33612, United States.; Florida Center of Excellence for Drug Discovery and Innovation, 3720 Spectrum Boulevard, Suite 305, Tampa, FL, 33612, United States., Kanwar A; Department of Chemistry, University of South Florida, Tampa, Florida, 33620, United States., Lewandowski EM; Department of Molecular Medicine, University of South Florida, Tampa, Florida, 33612, United States., Chen Y; Department of Molecular Medicine, University of South Florida, Tampa, Florida, 33612, United States. ychen1@health.usf.edu., Merkler DJ; Department of Chemistry, University of South Florida, Tampa, Florida, 33620, United States. merkler@usf.edu.

Publikováno v: Scientific reports [Sci Rep] 2017 Oct 18; Vol. 7 (1), pp. 13432. Date of Electronic Publication: 2017 Oct 18.