Zobrazeno 1 - 2 of 2 pro vyhledávání: '"Osmany Diaz-Bravo"'
1
Akademický článek
Molecular reshaping of phage-displayed Interleukin-2 at beta chain receptor interface to obtain potent super-agonists with improved developability profiles
Autor: Gertrudis Rojas, Ernesto Relova-Hernández, Annia Pérez-Riverón, Camila Castro-Martínez, Osmany Diaz-Bravo, Yanelys Cabrera Infante, Tania Gómez, Joaquín Solozábal, Ana Beatriz DíazBravo, Maren Schubert, Marlies Becker, Beatriz Pérez-Massón, Dayana Pérez-Martínez, Rydell Alvarez-Arzola, Osmany Guirola, Glay Chinea, Luis Graca, Stefan Dübel, Kalet León, Tania Carmenate
Publikováno v: Communications Biology, Vol 6, Iss 1, Pp 1-20 (2023)
Abstract Interleukin-2 (IL-2) engineered versions, with biased immunological functions, have emerged from yeast display and rational design. Here we reshaped the human IL-2 interface with the IL-2 receptor beta chain through the screening of phage-di
Externí odkaz: https://doaj.org/article/fc54223928184a9ab56c2dddb4e1f03a
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2
Akademický článek
Molecular reshaping of phage-displayed Interleukin-2 at beta chain receptor interface to obtain potent super-agonists with improved developability profiles.
Autor: Rojas, Gertrudis1 (AUTHOR) grojas@cim.sld.cu, Relova-Hernández, Ernesto1 (AUTHOR), Pérez-Riverón, Annia1 (AUTHOR), Castro-Martínez, Camila1 (AUTHOR), Diaz-Bravo, Osmany1 (AUTHOR), Infante, Yanelys Cabrera1 (AUTHOR), Gómez, Tania1 (AUTHOR), Solozábal, Joaquín1 (AUTHOR), DíazBravo, Ana Beatriz1 (AUTHOR), Schubert, Maren2 (AUTHOR), Becker, Marlies2 (AUTHOR), Pérez-Massón, Beatriz1 (AUTHOR), Pérez-Martínez, Dayana1 (AUTHOR), Alvarez-Arzola, Rydell1 (AUTHOR), Guirola, Osmany3 (AUTHOR), Chinea, Glay3 (AUTHOR), Graca, Luis4 (AUTHOR), Dübel, Stefan2 (AUTHOR), León, Kalet1 (AUTHOR), Carmenate, Tania1 (AUTHOR)
Publikováno v: Communications Biology. 8/9/2023, Vol. 6 Issue 1, p1-20. 20p.
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