Výsledky vyhledávání

Akademický článek

Utilization of computational methods for the identification of new natural inhibitors of human neutrophil elastase in inflammation therapy

Autor: Alzain Abdulrahim A., Elbadwi Fatima A., Al-Karmalawy Ahmed A., Elhag Rashid, Osman Wadah, Mothana Ramzi A.

Publikováno v: Open Chemistry, Vol 21, Iss 1, Pp 31736-44 (2023)

Human neutrophil elastase (HNE) plays a crucial role in causing tissue damage in various chronic and inflammatory disorders, making it a target for treating inflammatory diseases. While some inhibitors of HNE’s activity have been identified, only a

Externí odkaz: https://doaj.org/article/11fb72d28f03420b9b2722b895682199

Zobrazit plný text záznamu

Akademický článek

Insights into the molecular basis of some chalcone analogues as potential inhibitors of Leishmania donovani: An integrated in silico and in vitro study

Autor: Osman Marwa S., Awad Talal A., Shantier Shaza W., Garelnabi Elrashied A. E., Mukhtar Moawia M., Osman Wadah, Mothana Ramzi A., Elhag Rashid I.

Publikováno v: Open Chemistry, Vol 20, Iss 1, Pp 680-693 (2022)

Protozoal infections caused by species belonging to Leishmania donovani complex are responsible for the most severe form of leishmaniasis, especially in Sudan and other developing countries. Drugs commonly used for the treatment of the disease show v

Externí odkaz: https://doaj.org/article/4b345cbd3c7f417e95019d56d8358eee

Zobrazit plný text záznamu