The Tumor Microbiome Reacts to Hypoxia and Can Influence Response to Radiation Treatment in Colorectal Cancer.

Autor: Benej M; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Hoyd R; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Kreamer M; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Wheeler CE; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Grencewicz DJ; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Choueiry F; Department of Health Sciences, The Ohio State University, Columbus, Ohio., Chan CHF; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa., Zakharia Y; Division of Oncology, Hematology and Blood & Marrow Transplantation, Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa., Ma Q; Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio.; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Dodd RD; Department of Internal Medicine, University of Iowa, Iowa City, Iowa., Ulrich CM; Department of Population Health Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah., Hardikar S; Department of Population Health Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah., Churchman ML; Aster Insights, Hudson, Florida., Tarhini AA; Department of Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Robinson LA; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Singer EA; Department of Urologic Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Ikeguchi AP; Department of Hematology/Oncology, Stephenson Cancer Center of University of Oklahoma, Oklahoma City, Oklahoma., McCarter MD; Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado., Tinoco G; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Husain M; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Jin N; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Tan AC; Department of Oncological Science, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.; Department of Biomedical Informatics, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah., Osman AEG; Department of Internal Medicine, University of Utah, Salt Lake City, Utah., Eljilany I; Department of Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.; Clinical Science Lab, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Riedlinger G; Department of Precision Medicine, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey., Schneider BP; Indiana University Simon Comprehensive Cancer Center, Indianapolis, Indiana., Benejova K; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Kery M; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Papandreou I; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Zhu J; Department of Health Sciences, The Ohio State University, Columbus, Ohio., Denko N; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Spakowicz D; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.

Publikováno v: Cancer research communications [Cancer Res Commun] 2024 Jul 01; Vol. 4 (7), pp. 1690-1701.

A Bioinformatics Tool for Identifying Intratumoral Microbes from the ORIEN Dataset.

Autor: Wang C; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, Ohio., Ma A; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, Ohio.; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Li Y; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, Ohio., McNutt ME; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, Ohio., Zhang S; Department of Human Sciences, College of Education and Human Ecology, The Ohio State University, Columbus, Ohio., Zhu J; Department of Human Sciences, College of Education and Human Ecology, The Ohio State University, Columbus, Ohio., Hoyd R; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Wheeler CE; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Robinson LA; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Chan CHF; University of Iowa, Holden Comprehensive Cancer Center, Iowa City, Iowa., Zakharia Y; Division of Oncology, Hematology and Blood & Marrow Transplantation, University of Iowa, Holden Comprehensive Cancer Center, Iowa City, Iowa., Dodd RD; Department of Internal Medicine, University of Iowa, Iowa City, Iowa., Ulrich CM; Department of Population Health Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah., Hardikar S; Department of Population Health Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah., Churchman ML; Clinical & Life Sciences, M2GEN, Tampa, Florida., Tarhini AA; Departments of Cutaneous Oncology and Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Singer EA; Department of Urologic Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Ikeguchi AP; Department of Hematology/Oncology, Stephenson Cancer Center of University of Oklahoma, Oklahoma City, Oklahoma., McCarter MD; Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado., Denko N; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Tinoco G; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Husain M; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Jin N; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Osman AEG; Department of Internal Medicine, University of Utah, Salt Lake City, Utah., Eljilany I; Clinical Science Lab - Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Tan AC; Departments of Oncological Science and Biomedical Informatics, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah., Coleman SS; Departments of Oncological Science and Biomedical Informatics, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah., Denko L; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Riedlinger G; Department of Precision Medicine, Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey., Schneider BP; Indiana University Simon Comprehensive Cancer Center, Indianapolis, Indiana., Spakowicz D; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio., Ma Q; Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, Ohio.; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.

Publikováno v: Cancer research communications [Cancer Res Commun] 2024 Feb 05; Vol. 4 (2), pp. 293-302.

The tumor microbiome as a predictor of outcomes in patients with metastatic melanoma treated with immune checkpoint inhibitors.

Autor: Wheeler CE; Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Coleman SS 4th; Departments of Oncological Science and Biomedical Informatics, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Hoyd R; Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Denko L; Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Chan CHF; University of Iowa, Holden Comprehensive Cancer Center, Iowa City, IA, USA., Churchman ML; Clinical & Life Sciences, M2GEN, Tampa, FL, USA., Denko N; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Dodd RD; Department of Internal Medicine, University of Iowa, Iowa City, IA, USA., Eljilany I; Clinical Science Lab -- Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA., Hardikar S; Department of Population Health Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Husain M; Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Ikeguchi AP; Department of Hematology/Oncology, Stephenson Cancer Center of University of Oklahoma, Oklahoma City, OK, USA., Jin N; Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Ma Q; Department of Biomedical Informatics, The Ohio State University, Columbus, OH, USA., McCarter MD; Department of Surgery, University of Colorado School of Medicine, Aurora, CO, USA., Osman AEG; Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA., Robinson LA; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA., Singer EA; Department of Urologic Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Tinoco G; Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Ulrich CM; Department of Population Health Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Zakharia Y; Division of Oncology, Hematology and Blood & Marrow Transplantation, University of Iowa, Holden Comprehensive Cancer Center, Iowa City, IA, USA., Spakowicz D; Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.; Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Tarhini AA; Departments of Cutaneous Oncology and Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA., Tan AC; Departments of Oncological Science and Biomedical Informatics, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 May 25. Date of Electronic Publication: 2023 May 25.

Paired bone marrow and peripheral blood samples demonstrate lack of widespread dissemination of some CH clones.

Autor: Osman AEG; Division of Hematology and Hematologic Malignancies, The University of Utah, Salt Lake City, UT., Mencia-Trinchant N; Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY., Saygin C; Department of Medicine, Section of Hematology/Oncology, The University of Chicago, Chicago, IL., Moma L; Department of Medicine, Section of Hematology/Oncology, The University of Chicago, Chicago, IL., Kim A; Department of Medicine, Section of Hematology/Oncology, The University of Chicago, Chicago, IL., Housman G; Department of Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL., Pozsgai M; Department of Medicine, Section of Hematology/Oncology, The University of Chicago, Chicago, IL., Sinha E; Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY., Chandra P; Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY., Hassane DC; Department of Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL., Sboner A; Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY., Sangani K; Departments of Pathology and Pediatrics, Committee on Immunology, University of Chicago, Chicago, IL., DiNardi N; Departments of Pathology and Pediatrics, Committee on Immunology, University of Chicago, Chicago, IL., Johnson C; Department of Orthopedic Surgery, University of Chicago, Chicago, IL., Wallace SS; Department of Orthopedic Surgery, University of Chicago, Chicago, IL., Jabri B; Departments of Pathology and Pediatrics, Committee on Immunology, University of Chicago, Chicago, IL., Luu H; Department of Orthopedic Surgery, University of Chicago, Chicago, IL., Guzman ML; Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY., Desai P; Division of Hematology and Oncology, Weill Cornell Medical College, New York, NY., Godley LA; Department of Medicine, Section of Hematology/Oncology, The University of Chicago, Chicago, IL.

Publikováno v: Blood advances [Blood Adv] 2023 May 09; Vol. 7 (9), pp. 1910-1914.

Solitary manifestations of primary B-lymphoblastic lymphoma of the spine: Systematic literature review with case illustration.

Autor: Croci DM; Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, 175N Medical Drive East, Salt Lake City, UT 84132, USA. Electronic address: neuropub@hsc.utah.edu., Gamboa NT; Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, 175N Medical Drive East, Salt Lake City, UT 84132, USA., Osman AEG; Department of Internal Medicine, Division of Hematology & Hematologic Malignancies, 2000 Circle of Hope, Salt Lake City, UT 84112, USA., Maese L; Department of Pediatric Hematology and Oncology, University of Utah & Huntsman Cancer Institute, Salt Lake City, UT, USA., Mazur M; Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, 175N Medical Drive East, Salt Lake City, UT 84132, USA., Bisson EF; Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, 175N Medical Drive East, Salt Lake City, UT 84132, USA., Dailey AT; Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, 175N Medical Drive East, Salt Lake City, UT 84132, USA.

Publikováno v: Clinical neurology and neurosurgery [Clin Neurol Neurosurg] 2022 Jan; Vol. 212, pp. 107064. Date of Electronic Publication: 2021 Nov 24.