Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Osman, Morwan M"'
Autor:
Conrad, William H., Osman, Morwan M., Shanahan, Jonathan K., Chu, Frances, Takaki, Kevin K., Cameron, James, Hopkinson-Woolley, Digby, Brosch, Roland, Ramakrishnan, Lalita
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Feb 01. 114(6), 1371-1376.
Externí odkaz:
https://www.jstor.org/stable/26479223
Autor:
Osman, Morwan M.1 (AUTHOR), Pagán, Antonio J.1 (AUTHOR), Shanahan, Jonathan K.1 (AUTHOR), Ramakrishnan, Lalita1 (AUTHOR) lr404@cam.ac.uk
Publikováno v:
PLoS ONE. 7/23/2020, Vol. 15 Issue 7, p1-10. 10p.
Autor:
Osman, Morwan M, Shanahan, Jonathan, Chu, Frances, Takaki, Kevin, Pinckert, Malte L, Pag��n, Antonio J, Brosch, Roland, Conrad, William H, Ramakrishnan, Lalita
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (11), pp.e2122161119. ⟨10.1073/pnas.2122161119⟩
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (11), pp.e2122161119. ⟨10.1073/pnas.2122161119⟩
Mycobacterium tuberculosis and its close relative Mycobacterium marinum infect macrophages and induce the formation of granulomas, organized macrophage-rich immune aggregates. These mycobacterial pathogens can accelerate and co-opt granuloma formatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b87b7e6031f041289c2d7f109e13369e
https://www.repository.cam.ac.uk/handle/1810/335970
https://www.repository.cam.ac.uk/handle/1810/335970
Autor:
Osman, Morwan M., Pinckert, Malte L., Peak-Chew, Sew, Troll, Mark A., Conrad, William H., Ramakrishnan, Lalita
The type VII secretion system ESX-1 (ESAT-6 secretion system 1) is required for virulence in Mycobacterium tuberculosis and M. marinum . Here, we identify the clinical drug candidate ebselen as an inhibitor of ESX-1 secretion in both organisms. We fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=sharebioRxiv::bae66ee0574dd4d9268db31bf901c1f2
Akademický článek
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Akademický článek
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Autor:
Harrison, Suzanna H.1,2 (AUTHOR), Walters, Rowan C.1,2 (AUTHOR), Osman, Morwan M.1,2 (AUTHOR) morwan.osman@york.ac.uk, Springett, Roger J.3 (AUTHOR), Cook, Gregory M.4 (AUTHOR), Blaza, James N.1,2 (AUTHOR) jamie.blaza@york.ac.uk
Publikováno v:
BBA - Bioenergetics. 2024 Supplement, Vol. 1865, pN.PAG-N.PAG. 1p.
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0233252 (2020)
PLoS ONE, Vol 15, Iss 7, p e0233252 (2020)
Phthiocerol dimycocerosates (PDIMs) are a class of mycobacterial lipids that promote virulence in Mycobacterium tuberculosis and Mycobacterium marinum. It has recently been shown that PDIMs work in concert with the M. tuberculosis Type VII secretion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b478e0bcfcd2b44eb7d47b9cbc2bc3c
Autor:
Osman MM; Molecular Immunity Unit, Cambridge Institute of Therapeutic Immunology and Infectious Diseases, Department of Medicine, University of Cambridge, CB2 OQH Cambridge, United Kingdom.; Cell Biology Division, Medical Research Council Laboratory of Molecular Biology, CB2 0QH Cambridge, United Kingdom., Shanahan JK; Molecular Immunity Unit, Cambridge Institute of Therapeutic Immunology and Infectious Diseases, Department of Medicine, University of Cambridge, CB2 OQH Cambridge, United Kingdom.; Cell Biology Division, Medical Research Council Laboratory of Molecular Biology, CB2 0QH Cambridge, United Kingdom., Chu F; Department of Microbiology, University of Washington, Seattle, WA 98105., Takaki KK; Molecular Immunity Unit, Cambridge Institute of Therapeutic Immunology and Infectious Diseases, Department of Medicine, University of Cambridge, CB2 OQH Cambridge, United Kingdom.; Cell Biology Division, Medical Research Council Laboratory of Molecular Biology, CB2 0QH Cambridge, United Kingdom., Pinckert ML; Molecular Immunity Unit, Cambridge Institute of Therapeutic Immunology and Infectious Diseases, Department of Medicine, University of Cambridge, CB2 OQH Cambridge, United Kingdom.; Cell Biology Division, Medical Research Council Laboratory of Molecular Biology, CB2 0QH Cambridge, United Kingdom., Pagán AJ; Molecular Immunity Unit, Cambridge Institute of Therapeutic Immunology and Infectious Diseases, Department of Medicine, University of Cambridge, CB2 OQH Cambridge, United Kingdom.; Cell Biology Division, Medical Research Council Laboratory of Molecular Biology, CB2 0QH Cambridge, United Kingdom., Brosch R; Institut Pasteur, Université de Paris, CNRS UMR 3525, Unit for Integrated Mycobacterial Pathogenomics, 75724 Paris Cedex 15, France., Conrad WH; Molecular Immunity Unit, Cambridge Institute of Therapeutic Immunology and Infectious Diseases, Department of Medicine, University of Cambridge, CB2 OQH Cambridge, United Kingdom.; Cell Biology Division, Medical Research Council Laboratory of Molecular Biology, CB2 0QH Cambridge, United Kingdom., Ramakrishnan L; Molecular Immunity Unit, Cambridge Institute of Therapeutic Immunology and Infectious Diseases, Department of Medicine, University of Cambridge, CB2 OQH Cambridge, United Kingdom.; Cell Biology Division, Medical Research Council Laboratory of Molecular Biology, CB2 0QH Cambridge, United Kingdom.; Department of Microbiology, University of Washington, Seattle, WA 98105.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Mar 15; Vol. 119 (11), pp. e2122161119. Date of Electronic Publication: 2022 Mar 10.
Autor:
Lancaster SM; Department of Epidemiology, University of Washington, Seattle, Washington, USA., Schick UM; Department of Public Health Genetics, University of Washington, Seattle, Washington, USA., Osman MM; Department of Epidemiology, University of Washington, Seattle, Washington, USA., Enquobahrie DA; Department of Epidemiology, University of Washington, Seattle, Washington, USA.
Publikováno v:
Journal of clinical medicine research [J Clin Med Res] 2016 Aug; Vol. 8 (8), pp. 623. Date of Electronic Publication: 2016 Jul 01.