Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Oskar Popik"'
Autor:
Karol Molga, Sara Szymkuć, Patrycja Gołębiowska, Oskar Popik, Piotr Dittwald, Martyna Moskal, Rafal Roszak, Jacek Mlynarski, Bartosz A. Grzybowski
Publikováno v:
Nature Synthesis. 1:49-58
Autor:
Karl A. Scheidt, Patrycja Gołębiowska, Wiktor Beker, Olga Staszewska-Krajewska, Oskar Popik, Bartosz A. Grzybowski, Karol Molga, Ewa P. Gajewska, Milan Mrksich, Tomasz Badowski, Sara Szymkuć, Piotr Dittwald, Alison A. Bayly, Barbara Mikulak-Klucznik, Tomasz Klucznik, Jacek Mlynarski
Publikováno v:
Nature. 588:83-88
Training algorithms to computationally plan multistep organic syntheses has been a challenge for more than 50 years1-7. However, the field has progressed greatly since the development of early programs such as LHASA1,7, for which reaction choices at
Autor:
Sara Szymkuć, Bartosz A. Grzybowski, Jacek Mlynarski, Michał Startek, Ewa P. Gajewska, Oskar Popik, Piotr Dittwald
Publikováno v:
Chem. 6:280-293
Summary Whereas most organic molecules can be synthesized from progressively simpler substrates, syntheses of complex organic targets often involve counterintuitive sequence of steps that first complexify the structure but, by doing so, open up possi
Autor:
Oskar Popik, Adam S. Hogendorf, Mikołaj Matłoka, Rafal Moszczynski, Agnieszka Nikiforuk, Agnieszka Potasiewicz, Piotr Popik, Joanna Golebiowska, Jeffrey M. Witkin, Agata Kuziak, Shaun Yon-Seng Khoo
Although (S)-ketamine was approved for use in treatment-resistant depression in 2019, new preclinical findings suggest that (R)-ketamine might produce better efficacy and tolerability relative to (S)-ketamine. Here we evaluated the effects of (R)-, (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0f4c1a98b634c8feec99d9671ff685
https://doi.org/10.1016/j.pbb.2020.173011
https://doi.org/10.1016/j.pbb.2020.173011
Autor:
Bartłomiej Furman, Olga Staszewska-Krajewska, Marek Chmielewski, Oskar Popik, Barbara Grzeszczyk
Publikováno v:
Organicbiomolecular chemistry. 18(15)
Intramolecular Kinugasa reactions on in situ generated carbohydrate-derived alkynylnitrones are described. The effects of the length of chains, their mutual configuration, influence of experimental conditions on product distribution and feasibility o
Publikováno v:
ChemistryOpen
Herein we report a short and efficient protocol for the synthesis of naturally occurring higher‐carbon sugars—sedoheptulose (d‐altro‐hept‐2‐ulose) and d‐glycero‐l‐galacto‐oct‐2‐ulose—from readily available sugar aldehydes an
The synthesis of a legionaminic acid donor from N-acetyl neuraminic acid in fifteen steps and 17% overall yield is described. Activation of the adamantanyl thioglycoside in the donor with N-iodosuccinimide and trifluoromethanesulfonic acid in dichlor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb26c7cb5ea4ffddefef5e510e87572
https://europepmc.org/articles/PMC5545936/
https://europepmc.org/articles/PMC5545936/
Autor:
Marcin Górecki, Magdalena Jawiczuk, Jadwiga Frelek, Monika Pasternak-Suder, Oskar Popik, Jacek Mlynarski, Katarzyna Leśniak
Publikováno v:
The Journal of organic chemistry. 79(12)
This article presents comprehensive studies on the application of primary, secondary, and tertiary amines as e ffi cient organocatalysts for the de novo synthesis of ketoses and deoxyketoses. Mimicking the actions of aldolase enzymes, the synthesis o
Publikováno v:
ChemInform. 45
It is found that the serinamides (SBS) and (RBS) efficiently promote highly enantioselective syn-selective reaction of dihydroxyacetone with diverse aldehydes including optically pure ones.