Zobrazeno 1 - 10
of 881
pro vyhledávání: '"Oskar Hansson"'
Autor:
Lyduine E. Collij, Sophie E. Mastenbroek, Niklas Mattsson-Carlgren, Olof Strandberg, Ruben Smith, Shorena Janelidze, Sebastian Palmqvist, Rik Ossenkoppele, Oskar Hansson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Identifying concomitant Lewy body (LB) pathology through seed amplification assays (SAA) might enhance the diagnostic and prognostic work-up of Alzheimer’s disease (AD) in clinical practice and trials. This study examined whether LB pathol
Externí odkaz:
https://doaj.org/article/b424508f5d0d443ba15018c78ace4615
Autor:
Ondrej Lerch, Daniel Ferreira, Erik Stomrud, Danielle van Westen, Pontus Tideman, Sebastian Palmqvist, Niklas Mattsson-Carlgren, Jakub Hort, Oskar Hansson, Eric Westman
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder where pathophysiological changes begin decades before the onset of clinical symptoms. Analysis of brain atrophy patterns using structural MRI and multivariate
Externí odkaz:
https://doaj.org/article/40514354ff8e49bc8df96ba9fc69af5a
Autor:
Matthew D. Howe, Karysa J. Britton, Hannah E. Joyce, William Menard, Sheina Emrani, Zachary J. Kunicki, Melanie A. Faust, Brittany C. Dawson, Meghan C. Riddle, Edward D. Huey, Shorena Janelidze, Oskar Hansson, Stephen P. Salloway
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background With the approval of disease-modifying treatments (DMTs) for early Alzheimer’s disease (AD), there is an increased need for efficient and non-invasive detection methods for cerebral amyloid-β (Aβ) pathology. Current methods, i
Externí odkaz:
https://doaj.org/article/45714cef87b14c3381fb405472bc50ab
Autor:
Isabelle Glans, Katarina Nägga, Anna-Märta Gustavsson, Erik Stomrud, Peter M Nilsson, Olle Melander, Oskar Hansson, Sebastian Palmqvist
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Although several cardiovascular, demographic, genetic and lifestyle factors have been associated with cognitive function, little is known about what type of cognitive impairment they are associated with. The aim was to examine the
Externí odkaz:
https://doaj.org/article/fbd1cc4a0a784acbaa25cf7ce5a947a7
Autor:
Anna Orduña Dolado, Erik Stomrud, Nicholas J. Ashton, Johanna Nilsson, Clara Quijano-Rubio, Alexander Jethwa, Wagner S. Brum, Ann Brinkmalm Westman, Henrik Zetterberg, Kaj Blennow, Shorena Janelidze, Oskar Hansson
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Background Studies suggest that cerebrospinal fluid (CSF) levels of amyloid-β (Aβ)42 and Aβ40 present a circadian rhythm. However sustained sampling of large volumes of CSF with indwelling intrathecal catheters used in most of these studi
Externí odkaz:
https://doaj.org/article/f78a34bbdde94bdab236ffea02e7059b
Autor:
Sophie E. Mastenbroek, Jacob W. Vogel, Lyduine E. Collij, Geidy E. Serrano, Cécilia Tremblay, Alexandra L. Young, Richard A. Arce, Holly A. Shill, Erika D. Driver-Dunckley, Shyamal H. Mehta, Christine M. Belden, Alireza Atri, Parichita Choudhury, Frederik Barkhof, Charles H. Adler, Rik Ossenkoppele, Thomas G. Beach, Oskar Hansson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Lewy body (LB) diseases, characterized by the aggregation of misfolded α-synuclein proteins, exhibit notable clinical heterogeneity. This may be due to variations in accumulation patterns of LB neuropathology. Here we apply a data-driven di
Externí odkaz:
https://doaj.org/article/8ead8da20952462faeaafda287e2a07f
Autor:
Yoshiki Niimi, Shorena Janelidze, Kenichiro Sato, Naoki Tomita, Tadashi Tsukamoto, Takashi Kato, Kenji Yoshiyama, Hisatomo Kowa, Atsushi Iwata, Ryoko Ihara, Kazushi Suzuki, Kensaku Kasuga, Takeshi Ikeuchi, Kenji Ishii, Kengo Ito, Akinori Nakamura, Michio Senda, Theresa A. Day, Samantha C. Burnham, Leonardo Iaccarino, Michael J. Pontecorvo, Oskar Hansson, Takeshi Iwatsubo
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Maximizing the efficiency to screen amyloid-positive individuals in asymptomatic and non-demented aged population using blood-based biomarkers is essential for future success of clinical trials in the early stage of Alzheimer’s
Externí odkaz:
https://doaj.org/article/d12e8157ca6b40da9d6b4f81cfd4802f
Autor:
Linda Karlsson, Jacob Vogel, Ida Arvidsson, Kalle Åström, Shorena Janelidze, Kaj Blennow, Sebastian Palmqvist, Erik Stomrud, Niklas Mattsson-Carlgren, Oskar Hansson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Cerebrospinal fluid (CSF) biomarkers reflect brain pathophysiology and are used extensively in translational research as well as in clinical practice for diagnosis of neurological diseases, e.g., Alzheimer’s disease (AD). However, CSF biom
Externí odkaz:
https://doaj.org/article/83a754f4856845649154ab6fc1777235
Autor:
Alexander F. Santillo, Tor O. Strandberg, Nina H. Reislev, Markus Nilsson, Erik Stomrud, Nicola Spotorno, Danielle van Westen, Oskar Hansson
Publikováno v:
NeuroImage, Vol 296, Iss , Pp 120672- (2024)
Age-related white matter hyperintensities are a common feature and are known to be negatively associated with structural integrity, functional connectivity, and cognitive performance. However, this has yet to be fully understood mechanistically. We a
Externí odkaz:
https://doaj.org/article/ffa8bb1dfc934fd8b565fe36e837e2d4
Autor:
Ida Arvidsson, Olof Strandberg, Sebastian Palmqvist, Erik Stomrud, Nicholas Cullen, Shorena Janelidze, Pontus Tideman, Anders Heyden, Karl Åström, Oskar Hansson, Niklas Mattsson-Carlgren
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background Predicting future Alzheimer’s disease (AD)-related cognitive decline among individuals with subjective cognitive decline (SCD) or mild cognitive impairment (MCI) is an important task for healthcare. Structural brain imaging as m
Externí odkaz:
https://doaj.org/article/49a2d49cc014492c8756c4880a8e5d5c