The Psychosis Metabolic Risk Calculator (PsyMetRiC) for Young People with Psychosis: International External Validation and Site-Specific Recalibration in Two Independent European Samples

Autor: Benjamin I. Perry, Frederik Vandenberghe, Nathalia Garrido-Torres, Emanuele F. Osimo, Marianna Piras, Javier Vazquez-Bourgon, Rachel Upthegrove, Claire Grosu, Victor Ortiz-Garcia De La Foz, Peter B. Jones, Nermine Laaboub, Miguel Ruiz-Veguilla, Jan Stochl, Celine Dubath, Manuel Canal-Rivero, Pavan Mallikarjun, Aurélie Delacrétaz, Nicolas Ansermot, Emilio Fernandez-Egea, Severine Crettol, Franziska Gamma, Kerstin J. Plessen, Philippe Conus, Golam M. Khandaker, Graham K. Murray, Chin B. Eap, Benedicto Crespo-Facorro

Publikováno v: The Lancet regional health. Europe, vol. 22, pp. 100493

[Background]: Cardiometabolic dysfunction is common in young people with psychosis. Recently, the Psychosis Metabolic Risk Calculator (PsyMetRiC) was developed and externally validated in the UK, predicting up-to six-year risk of metabolic syndrome (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbea01b0e18ac2dbb515f4393b215a3
https://www.repository.cam.ac.uk/handle/1810/341524

Contribution of severe mental disorders to fatally harmful effects of physical disorders: national cohort study.

Autor: Formánek T; Department of Psychiatry, University of Cambridge, Cambridge, UK; and Department of Public Mental Health, National Institute of Mental Health, Klecany, Czech Republic., Krupchanka D; Department of Mental Health and Substance Use, World Health Organization, Geneva, Switzerland., Perry BI; Department of Psychiatry, University of Cambridge, Cambridge, UK; and Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK., Mladá K; Department of Public Mental Health, National Institute of Mental Health, Klecany, Czech Republic; and Department of Psychiatry, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic., Osimo EF; Department of Psychiatry, University of Cambridge, Cambridge, UK; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK; Institute of Clinical Sciences, Imperial College, London, UK; MRC London Institute of Medical Sciences, London, UK; and South London and Maudsley NHS Foundation Trust, London, UK., Masopust J; Department of Psychiatry, University Hospital Hradec Králové, Hradec Králové, Czech Republic; and Faculty of Medicine, Charles University, Hradec Králové, Czech Republic., Jones PB; Department of Psychiatry, University of Cambridge, Cambridge, UK; and Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK., Plana-Ripoll O; Department of Clinical Epidemiology, Aarhus University, Aarhus, Denmark; Aarhus University Hospital, Aarhus, Denmark; and National Centre for Register-based Research, Aarhus University, Aarhus, Denmark.

Publikováno v: The British journal of psychiatry : the journal of mental science [Br J Psychiatry] 2024 Oct; Vol. 225 (4), pp. 436-445.

Assessing the generalisability of the psychosis metabolic risk calculator (PsyMetRiC) for young people with first-episode psychosis with validation in a Hong Kong Chinese Han population: a 4-year follow-up study.

Autor: Tse W; Department of Psychiatry, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China., Khandaker GM; Bristol Medical School, University of Bristol, Bristol, England., Zhou H; Department of Psychiatry, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.; Department of Social Work and Social Administration, Faculty of Social Sciences, The University of Hong Kong, Hong Kong Special Administrative Region, China., Luo H; Department of Social Work and Social Administration, Faculty of Social Sciences, The University of Hong Kong, Hong Kong Special Administrative Region, China., Yan WC; Department of Psychiatry, Kowloon Hospital, Hong Kong Special Administrative Region, China., Siu MW; Department of Psychiatry, Kowloon Hospital, Hong Kong Special Administrative Region, China., Poon LT; Department of Psychiatry, United Christian Hospital, Hong Kong Special Administrative Region, China., Lee EHM; Department of Psychiatry, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China., Zhang Q; Musketeers Foundation Institute of Data Science, The University of Hong Kong, Hong Kong Special Administrative Region, China.; Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China., Upthegrove R; Institute for Mental Health, University of Birmingham, England., Osimo EF; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge, England.; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, England., Perry BI; Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge, England.; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, England., Chan SKW; Department of Psychiatry, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.; The State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong Special Administrative Region, China.

Publikováno v: The Lancet regional health. Western Pacific [Lancet Reg Health West Pac] 2024 May 14; Vol. 47, pp. 101089. Date of Electronic Publication: 2024 May 14 (Print Publication: 2024).

Effect of polygenic risk for schizophrenia on cardiac structure and function: a UK Biobank observational study.

Autor: Pillinger T; Institute of Psychiatry, Psychology and Neuroscience, Department of Psychosis Studies, King's College London, London, UK; Psychiatric Imaging Group, Imperial College London, London, UK. Electronic address: toby.pillinger@kcl.ac.uk., Osimo EF; Department of Psychiatry, University of Cambridge, Cambridge, UK; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK; Psychiatric Imaging Group, Imperial College London, London, UK., de Marvao A; British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine and Sciences, King's College London, London, UK; Department of Women and Children's Health, King's College London, London, UK., Shah M; Computational Cardiac Imaging Group, Imperial College London, London, UK., Francis C; MRC London Institute of Medical Sciences, Department of Cardiovascular Genetics and Genomics, National Heart and Lung Institute, Imperial College London, London, UK; Royal Brompton Hospital, Royal Brompton and Harefield NHS Foundation Trust, Uxbridge, UK., Huang J; Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK; Singapore Institute for Clinical Sciences (SICS), the Agency for Science, Technology and Research (A*STAR), Singapore., D'Ambrosio E; Institute of Psychiatry, Psychology and Neuroscience, Department of Psychosis Studies, King's College London, London, UK; Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari 'Aldo Moro', Italy., Firth J; Division of Psychology and Mental Health, University of Manchester, and Greater Manchester Mental Health NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Nour MM; Institute of Psychiatry, Psychology and Neuroscience, Department of Psychosis Studies, King's College London, London, UK; Max Planck University College London Centre for Computational Psychiatry and Ageing Research, and Wellcome Trust Centre for Human Neuroimaging, University College London, London, UK; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK., McCutcheon RA; Institute of Psychiatry, Psychology and Neuroscience, Department of Psychosis Studies, King's College London, London, UK; Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK., Pardiñas AF; MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK., Matthews PM; Department of Brain Sciences and UK Dementia Research Institute Centre, Imperial College London, London, UK., O'Regan DP; Computational Cardiac Imaging Group, Imperial College London, London, UK., Howes OD; Department of Psychological Medicine, King's College London, London, UK; Psychiatric Imaging Group, Imperial College London, London, UK; H Lundbeck A/S, St Albans, UK.

Publikováno v: The lancet. Psychiatry [Lancet Psychiatry] 2023 Feb; Vol. 10 (2), pp. 98-107. Date of Electronic Publication: 2023 Jan 08.

The psychosis metabolic risk calculator (PsyMetRiC) for young people with psychosis: International external validation and site-specific recalibration in two independent European samples.

Autor: Perry BI; Department of Psychiatry, University of Cambridge, Cambridge, England, United Kingdom.; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, England, United Kingdom., Vandenberghe F; Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Prilly, Switzerland., Garrido-Torres N; Virgen del Rocío University Hospital, Network Centre for Biomedical Research in Mental Health (CIBERSAM), Institute of Biomedicine of Seville (IBiS), University of Seville, First-episode Psychosis Research Network of Andalusia (Red PEPSur), Spain., Osimo EF; Department of Psychiatry, University of Cambridge, Cambridge, England, United Kingdom.; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, England, United Kingdom.; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Imperial College, Hammersmith Campus, London, England, United Kingdom., Piras M; Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Prilly, Switzerland., Vazquez-Bourgon J; Virgen del Rocío University Hospital, Network Centre for Biomedical Research in Mental Health (CIBERSAM), Institute of Biomedicine of Seville (IBiS), University of Seville, First-episode Psychosis Research Network of Andalusia (Red PEPSur), Spain.; Department of Psychiatry, Marques de Valdecilla University Hospital, Institute of Biomedicine Marqués de Valdecilla (IDIVAL), Universidad de Cantabria, Santander, Spain., Upthegrove R; Institute for Mental Health and Centre for Human Brain Health, University of Birmingham, Birmingham, England, United Kingdom.; Early Intervention Service, Birmingham Womens and Childrens NHS Foundation Trust., Grosu C; Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Prilly, Switzerland., De La Foz VO; Department of Psychiatry, Marques de Valdecilla University Hospital, Institute of Biomedicine Marqués de Valdecilla (IDIVAL), Universidad de Cantabria, Santander, Spain., Jones PB; Department of Psychiatry, University of Cambridge, Cambridge, England, United Kingdom.; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, England, United Kingdom., Laaboub N; Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Prilly, Switzerland., Ruiz-Veguilla M; Virgen del Rocío University Hospital, Network Centre for Biomedical Research in Mental Health (CIBERSAM), Institute of Biomedicine of Seville (IBiS), University of Seville, First-episode Psychosis Research Network of Andalusia (Red PEPSur), Spain., Stochl J; Department of Psychiatry, University of Cambridge, Cambridge, England, United Kingdom.; Department of Kinanthropology, Charles University, Prague, Czech Republic., Dubath C; Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Prilly, Switzerland., Canal-Rivero M; Virgen del Rocío University Hospital, Network Centre for Biomedical Research in Mental Health (CIBERSAM), Institute of Biomedicine of Seville (IBiS), University of Seville, First-episode Psychosis Research Network of Andalusia (Red PEPSur), Spain., Mallikarjun P; Institute for Mental Health and Centre for Human Brain Health, University of Birmingham, Birmingham, England, United Kingdom., Delacrétaz A; Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Prilly, Switzerland., Ansermot N; Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Prilly, Switzerland., Fernandez-Egea E; Department of Psychiatry, University of Cambridge, Cambridge, England, United Kingdom.; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, England, United Kingdom., Crettol S; Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Prilly, Switzerland., Gamma F; Les Toises Psychiatry and Psychotherapy Centre, Lausanne, Switzerland., Plessen KJ; Service of Child and Adolescent Psychiatry, Department of Psychiatry, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland., Conus P; Service of General Psychiatry, Department of Psychiatry, Lausanne University Hospital, University of Lausanne, Prilly, Switzerland., Khandaker GM; Department of Psychiatry, University of Cambridge, Cambridge, England, United Kingdom.; Centre for Academic Mental Health, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England, United Kingdom.; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England, United Kingdom., Murray GK; Department of Psychiatry, University of Cambridge, Cambridge, England, United Kingdom.; Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, England, United Kingdom., Eap CB; Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Prilly, Switzerland.; School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland.; Center for Research and Innovation in Clinical Pharmaceutical Sciences, Lausanne University Hospital and University of Lausanne, Switzerland.; Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, University of Lausanne, Geneva, Switzerland., Crespo-Facorro B; Virgen del Rocío University Hospital, Network Centre for Biomedical Research in Mental Health (CIBERSAM), Institute of Biomedicine of Seville (IBiS), University of Seville, First-episode Psychosis Research Network of Andalusia (Red PEPSur), Spain.

Publikováno v: The Lancet regional health. Europe [Lancet Reg Health Eur] 2022 Aug 19; Vol. 22, pp. 100493. Date of Electronic Publication: 2022 Aug 19 (Print Publication: 2022).