Real-World Evidence to Assess Medication Safety or Effectiveness in Children: Systematic Review

Autor: Tamar Lasky, Bruce Carleton, Daniel B. Horton, Lauren E. Kelly, Dimitri Bennett, Angela S. Czaja, Dina Gifkins, Osemeke U. Osokogu, Ann W. McMahon

Publikováno v: Drugs - Real World Outcomes, Vol 7, Iss 2, Pp 97-107 (2020)

Abstract Background The promise of real-world evidence (RWE) is especially relevant to pediatrics, where medicines prescribed for children are often used without evidence derived from randomized clinical trials. Objectives The aim of this systematic

Externí odkaz: https://doaj.org/article/0354b3c3d9834ed9b340c65340f87ffd

Masking by vaccines in pediatric drug safety signal detection in the EudraVigilance database

Autor: Daniel Weibel, Carmen Ferrajolo, Caitlin Dodd, Benedikt F.H. Becker, Alexandra Pacurariu, Jan A. Kors, Dang H. Vo, Osemeke U. Osokogu, Miriam C. J. M. Sturkenboom

Publikováno v: Pharmacoepidemiology and Drug Safety, 27(11), 1249-1256. John Wiley & Sons Ltd.
Pharmacoepidemiology and Drug Safety, 27(11), 1249. John Wiley and Sons Ltd

Purpose: Postmarketing drug safety surveillance relies upon measures of disproportionate reporting in spontaneous reporting systems. It has been hypothesized that products or events reported frequently may "mask" signals. Methods: We analyzed the mas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48db827a545c5bdb0493c749cc71288a
https://doi.org/10.1002/pds.4623

Current needs in pediatric pharmacoepidemiology

Autor: Katia M.C. Verhamme, Al Artaman, Rachel E. Sobel, Sonia S. Maruti, Tamar Lasky, Osemeke U. Osokogu, Angela S. Czaja

Publikováno v: Pharmacoepidemiology and Drug Safety. 25:738-742

Purpose We report on a needs assessment conducted by the International Society of Pharmacoepidemiology (ISPE) Pediatric Special Interest Group (SIG) to identify critical needs in pediatric pharmacoepidemiology and directions for future activities. Me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a2482647706af8f3c6e5d5509378e166
https://doi.org/10.1002/pds.3985

Comparing drug effectiveness in children: A systematic review

Autor: Miriam C. J. M. Sturkenboom, Carmen Ferrajolo, Osemeke U. Osokogu, Krupa Patel, Julijana Dukanovic

Publikováno v: Pharmacoepidemiology and Drug Safety, 27(12), 1295-1301. John Wiley & Sons Ltd.

Purpose: The purpose of the study is to assess the current state of the art in pediatric comparative effectiveness research, potential gaps, and areas for improvement. Methods: Relevant articles from inception to February 2015 were retrieved from Emb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f4ce20a0e3b7d2ed33f0cf15bce0a8
https://pure.eur.nl/en/publications/1fc6965b-bbbc-4bd3-91b1-092e53666ac7

Choice of time period to identify confounders for propensity score matching, affected the estimate: a retrospective cohort study of drug effectiveness in asthmatic children

Autor: Javeed Khan, Miriam C. J. M. Sturkenboom, Daniel Weibel, Katia M.C. Verhamme, Osemeke U. Osokogu, Swabra Nakato, Maria A. J. de Ridder

Publikováno v: Journal of Clinical Epidemiology, 101, 107-115. Elsevier Inc.

Objectives To control for confounding by indication in comparative (drug) effectiveness studies, propensity score (PS) methods may be used. Since childhood diseases or outcomes often present as acute events, we compared the effect of using different

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43596754adf1f993a09d6e335e9acdf9
https://doi.org/10.1016/j.jclinepi.2018.01.008