Heteromultimeric sarbecovirus receptor binding domain immunogens primarily generate variant-specific neutralizing antibodies.

Autor: Zang T; Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065.; HHMI, The Rockefeller University, New York, NY 10065., Osei Kuffour E; Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065., Baharani VA; Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065.; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065., Canis M; Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065., Schmidt F; Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065., Da Silva J; Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065., Lercher A; Laboratory of Virology and Infectious Diseases, The Rockefeller University, New York, NY 10065., Chaudhary P; Laboratory of Virology and Infectious Diseases, The Rockefeller University, New York, NY 10065., Hoffmann HH; Laboratory of Virology and Infectious Diseases, The Rockefeller University, New York, NY 10065., Gazumyan A; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065., Miranda IC; Laboratory of Comparative Pathology, The Rockefeller University, New York, NY 10065., MacDonald MR; Laboratory of Virology and Infectious Diseases, The Rockefeller University, New York, NY 10065., Rice CM; Laboratory of Virology and Infectious Diseases, The Rockefeller University, New York, NY 10065., Nussenzweig MC; HHMI, The Rockefeller University, New York, NY 10065.; Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065., Hatziioannou T; Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065., Bieniasz PD; Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065.; HHMI, The Rockefeller University, New York, NY 10065.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Dec 19; Vol. 120 (51), pp. e2317367120. Date of Electronic Publication: 2023 Dec 14.

USP18 (UBP43) Abrogates p21-Mediated Inhibition of HIV-1.

Autor: Osei Kuffour E; Clinic of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany., Schott K; Host-Pathogen Interactions, Paul-Ehrlich-Institut, Langen, Germany., Jaguva Vasudevan AA; Clinic of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany., Holler J; Department of Pediatrics, Emory University, Atlanta, Georgia, USA., Schulz WA; Department of Urology, Medical Faculty, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany., Lang PA; Department for Molecular Medicine II, Medical Faculty, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany., Lang KS; Institute of Immunology, University Hospital, University of Duisburg-Essen, Essen, Germany., Kim B; Department of Pediatrics, Emory University, Atlanta, Georgia, USA.; Department of Pharmacy, Kyunghee University, Seoul, South Korea., Häussinger D; Clinic of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany., König R; Host-Pathogen Interactions, Paul-Ehrlich-Institut, Langen, Germany.; Immunity and Pathogenesis Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, USA., Münk C; Clinic of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany carsten.muenk@med.uni-duesseldorf.de.

Publikováno v: Journal of virology [J Virol] 2018 Sep 26; Vol. 92 (20). Date of Electronic Publication: 2018 Sep 26 (Print Publication: 2018).