Výsledky vyhledávání - "Oscar Tejada"

Akademický článek

Folate deficiency increases the incidence of dolutegravir-associated foetal defects in a mouse pregnancy modelResearch in context

Autor: Haneesha Mohan, Jessica Nguyen, Ben MacKenzie, Audrey Yee, Evelyn Yukino Laurette, Tanvi Sanghvi, Oscar Tejada, Valeriya Dontsova, Kit-Yi Leung, Cameron Goddard, Taylor De Young, John G. Sled, Nicholas D.E. Greene, Andrew J. Copp, Lena Serghides

Publikováno v: EBioMedicine, Vol 95, Iss , Pp 104762- (2023)

Summary: Background: Dolutegravir (DTG) is a recommended first-line regimen for all people with Human Immunodeficiency Virus (HIV) infection. Initial findings from Botswana, a country with no folate fortification program, showed an elevated prevalenc

Externí odkaz: https://doaj.org/article/7e048acef5e94323b030a6a4ee465c56

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Akademický článek

Dolutegravir in pregnant mice is associated with increased rates of fetal defects at therapeutic but not at supratherapeutic levels

Autor: Haneesha Mohan, Monica Guzman Lenis, Evelyn Y. Laurette, Oscar Tejada, Tanvi Sanghvi, Kit-Yi Leung, Lindsay S. Cahill, John G. Sled, Paul Delgado-Olguín, Nicholas D.E. Greene, Andrew J. Copp, Lena Serghides

Publikováno v: EBioMedicine, Vol 63, Iss , Pp 103167- (2021)

Background: Dolutegravir (DTG) is a preferred regimen for all people with HIV including pregnant women, but its effects on the fetus are not fully understood. Periconceptional exposure to DTG has been associated with increased rates of neural tube de

Externí odkaz: https://doaj.org/article/b67b5396b8d6461f9d661ea55cd7e4fb

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Dolutegravir in pregnant mice is associated with increased rates of fetal defects at therapeutic but not at supratherapeutic levels

Autor: John G. Sled, Lena Serghides, Tanvi Sanghvi, Evelyn Y. Laurette, Oscar Tejada, Paul Delgado-Olguin, Haneesha Mohan, Kit-Yi Leung, Monica S. Guzman Lenis, Nicholas D. E. Greene, Lindsay S. Cahill, Andrew J. Copp

Publikováno v: EBioMedicine
EBioMedicine, Vol 63, Iss, Pp 103167-(2021)

Background Dolutegravir (DTG) is a preferred regimen for all people with HIV including pregnant women, but its effects on the fetus are not fully understood. Periconceptional exposure to DTG has been associated with increased rates of neural tube def

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad0cdecbab52b131b2b7210d319aa72b
https://doi.org/10.1016/j.ebiom.2020.103167

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