Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Oscar Reina"'
Autor:
Paula Bujosa, Oscar Reina, Adrià Caballé, Anna Casas-Lamesa, Mònica Torras-Llort, Juan Pérez-Roldán, Ana Silvina Nacht, Guillermo P. Vicent, Jordi Bernués, Fernando Azorín
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114137- (2024)
Summary: Chromatin-associated RNAs (cRNAs) are a poorly characterized fraction of cellular RNAs that co-purify with chromatin. Their full complexity and the mechanisms regulating their packaging and chromatin association remain poorly understood. Her
Externí odkaz:
https://doaj.org/article/f614dbef4fd84e8cbf7f94063b1580af
Autor:
Berta Duran-Arqué, Manuel Cañete, Chiara Lara Castellazzi, Anna Bartomeu, Anna Ferrer-Caelles, Oscar Reina, Adrià Caballé, Marina Gay, Gianluca Arauz-Garofalo, Eulalia Belloc, Raúl Mendez
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-27 (2022)
Abstract Background Vertebrate CPEB proteins bind mRNAs at cytoplasmic polyadenylation elements (CPEs) in their 3′ UTRs, leading to cytoplasmic changes in their poly(A) tail lengths; this can promote translational repression or activation of the mR
Externí odkaz:
https://doaj.org/article/f2d44e0e32c84e0b8bb39e127da46f6f
Autor:
Clara Suñer, Annarita Sibilio, Judit Martín, Chiara Lara Castellazzi, Oscar Reina, Ivan Dotu, Adrià Caballé, Elisa Rivas, Vittorio Calderone, Juana Díez, Angel R Nebreda, Raúl Méndez
Publikováno v:
eLife, Vol 11 (2022)
Chronic inflammation is a major cause of disease. Inflammation resolution is in part directed by the differential stability of mRNAs encoding pro-inflammatory and anti-inflammatory factors. In particular, tristetraprolin (TTP)-directed mRNA deadenyla
Externí odkaz:
https://doaj.org/article/4e3e383266cb49608da7a9a2ea87fedf
Autor:
Nuria Pell, Ester Garcia-Pras, Javier Gallego, Salvador Naranjo-Suarez, Alexandra Balvey, Clara Suñer, Marcos Fernandez-Alfara, Veronica Chanes, Julia Carbo, Marta Ramirez-Pedraza, Oscar Reina, Louise Thingholm, Corinna Bang, Malte Rühlemann, Andre Franke, Robert Schierwagen, Karl P. Rheinwalt, Jonel Trebicka, Raul Mendez, Mercedes Fernandez
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101388- (2021)
Objective: Obesity represents a growing health problem that is reaching pandemic dimensions and lacks effective cures, thus highlighting an urgent need for better mechanistic understanding and new therapeutic strategies. Unlike transcription, the fun
Externí odkaz:
https://doaj.org/article/86a68fa47e414fe0a0f7d694e72e9894
Publikováno v:
PLoS Genetics, Vol 16, Iss 8, p e1008962 (2020)
Haspin, a highly conserved kinase in eukaryotes, has been shown to be responsible for phosphorylation of histone H3 at threonine 3 (H3T3ph) during mitosis, in mammals and yeast. Here we report that haspin is the kinase that phosphorylates H3T3 in Dro
Externí odkaz:
https://doaj.org/article/6a69de1b67f34e63b158464b0f8f2779
Publikováno v:
Cell Reports, Vol 21, Iss 11, Pp 3178-3189 (2017)
Drosophila spermatogenesis constitutes a paradigmatic system to study maintenance, proliferation, and differentiation of adult stem cell lineages. Each Drosophila testis contains 6–12 germ stem cells (GSCs) that divide asymmetrically to produce gon
Externí odkaz:
https://doaj.org/article/fce16436d9c049a5a4fc2c26c1c0068d
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
While structural importance of linker histone H1 in packaging eukaryotic genome into chromatin is well known, its biological function remains poorly understood. Here the authors reveal that Drosophila linker histone H1 prevents DNA:RNA hybrids accumu
Externí odkaz:
https://doaj.org/article/54e92716a1c5421ab62720cdc86bee36
Autor:
Delphine Casabonne, Oscar Reina, Yolanda Benavente, Nikolaus Becker, Marc Maynadié, Lenka Foretová, Pierluigi Cocco, Anna González-Neira, Alexandra Nieters, Paolo Boffetta, Jaap M. Middeldorp, Silvia de Sanjose
Publikováno v:
Haematologica, Vol 96, Iss 2 (2011)
Using EpiLymph case-control data, we found that chronic lymphocytic leukemia patients were more likely to have abnormal reactive serological patterns to Epstein Barr virus than controls. Here, we aimed to assess whether this association is modified b
Externí odkaz:
https://doaj.org/article/7185aef71c4e403ead7afe996a1706a3
Autor:
Xavier Solé, Núria Bonifaci, Núria López-Bigas, Antoni Berenguer, Pilar Hernández, Oscar Reina, Christopher A Maxwell, Helena Aguilar, Ander Urruticoechea, Silvia de Sanjosé, Francesc Comellas, Gabriel Capellá, Víctor Moreno, Miguel Angel Pujana
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4544 (2009)
Gene expression profiling has identified cancer prognostic and predictive signatures with superior performance to conventional histopathological or clinical parameters. Consequently, signatures are being incorporated into clinical practice and will s
Externí odkaz:
https://doaj.org/article/20d0f19f31fa4a788ea07ceecd3a2d37
Autor:
Elias Campo, Silvia de Sanjosé, Emili Montserrat, Miguel A. Pujana, Africa García-Orad, Pedro Jares, Maria T. Ardanaz, Oscar Reina, Susana Pérez-Álvarez, Dolors Colomer, Idoia Martín-Guerrero, Francesc Bosch, Yolanda Benavente, Anna Enjuanes
Supplementary Table 2 from Genetic Variants in Apoptosis and Immunoregulation-Related Genes Are Associated with Risk of Chronic Lymphocytic Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9ec7f6a6783153f8098a80a8f1ae5d
https://doi.org/10.1158/0008-5472.22376457.v1
https://doi.org/10.1158/0008-5472.22376457.v1