Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Oscar R. Colamonici"'
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87620 (2014)
Cell cycle transitions are governed by the timely expression of cyclins, the activating subunits of Cyclin-dependent kinases (Cdks), which are responsible for the inactivation of the pocket proteins. Overexpression of cyclins promotes cell proliferat
Externí odkaz:
https://doaj.org/article/a0a8d99176f94f01bacd3f55e938e0b9
Autor:
Jiwang Chen, Marcelo G. Bonini, Suellen D. S. Oliveira, Oscar R. Colamonici, Richard D. Minshall, Maricela Castellon, Olga Chernaya, Roberto Machado
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d456481a2cbd3ca1584e0cc006ec0550
https://doi.org/10.1096/fasebj.2018.32.1_supplement.573.9
https://doi.org/10.1096/fasebj.2018.32.1_supplement.573.9
Publikováno v:
Experimental Cell Research. 315:2914-2920
Mip130/LIN-9 is part of a large complex that includes homologs of the Drosophila dREAM (drosophila RB-like, E2F, and Myb) and C. elegans DRM complexes. This complex also includes proteins such as Mip40/LIN-37, Mip120/LIN-54, and LIN-52. In mammalian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f648d0c5d411995f2ef304b54aadd39
https://doi.org/10.1016/j.yexcr.2009.07.014
https://doi.org/10.1016/j.yexcr.2009.07.014
Publikováno v:
Journal of Biological Chemistry. 282:168-175
Members of the novel family of proteins that include Drosophila Mip130, Caenorhabditis elegans LIN-9, and mammalian LIN-9 intervene in different cellular functions such as regulation of transcription, differentiation, transformation, and cell cycle p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5160c112f1199cdf50208a8d184294a1
https://doi.org/10.1074/jbc.m609924200
https://doi.org/10.1074/jbc.m609924200
Autor:
Yasuji Mori, Alo Nag, Oscar R. Colamonici, Andrei L. Gartel, Wei Pan, Nissim Hay, Pradip Raychaudhuri, Abhishek Datta
Publikováno v:
Journal of Biological Chemistry. 279:36698-36707
The tumor suppressor protein ARF (alternate reading frame) inhibits MDM2 to stabilize and activate the functions of p53. Here we provide evidence for an additional activity of ARF that attenuates cell cycle progression independently of p53 activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2547c77df643c23821e86d633efb758
https://doi.org/10.1074/jbc.m312305200
https://doi.org/10.1074/jbc.m312305200
Autor:
Mark Pilkinton, Jiaping Xue, Debra Salvi, Hiroaki Kiyokawa, Oscar R. Colamonici, Raudel Sandoval
Publikováno v:
Journal of Biological Chemistry. 279:32275-32280
The regulation of cell growth is one of the most important effects of type I interferons (IFNs). This response may involve a cytostatic effect or the induction of apoptosis depending on the cell context. Often the growth-inhibitory response of type I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::038931cf8329483726568a5ab5fb0d93
https://doi.org/10.1074/jbc.m313830200
https://doi.org/10.1074/jbc.m313830200
Autor:
Lewis C. Cantley, Lynda A. Morrison, T Sarma, David A. Fruman, B Hemmings, R M Buller, C Prejean, Oscar R. Colamonici, O Kurnasov, Anna Usacheva
Publikováno v:
The Journal of Immunology. 167:4553-4559
The Janus kinase/STAT pathway has emerged as the paradigm of IFN-induced protection from viral infections. However, the possible participation of other signaling proteins in this protection is not clearly understood. In this report, we demonstrate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fd1e2322a0bb274850049dbd38a54e
https://doi.org/10.4049/jimmunol.167.8.4553
https://doi.org/10.4049/jimmunol.167.8.4553
Publikováno v:
Journal of Interferon & Cytokine Research. 20:479-485
Despite accumulating information about the different effector molecules and signaling cascades that are invoked on interferon-alpha (IFN-alpha) binding to the type 1 IFN receptor, little is known about the specifics of the binding interactions betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75eb98b758eea8a45ef8a340eb82ada9
https://doi.org/10.1089/10799900050023898
https://doi.org/10.1089/10799900050023898
Autor:
Christine Prejean, Oscar R. Colamonici
Publikováno v:
Seminars in Cancer Biology. 10:83-92
Type I interferons are imperative in maintaining a defense against viral infection. These cytokines also play an important role in the control of cell proliferation. These effects are triggered by ligand binding to a specific cell surface receptor. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80cfbac1f768499da9b63751d4359f38
https://doi.org/10.1006/scbi.2000.0311
https://doi.org/10.1006/scbi.2000.0311
Autor:
Hans R. Figulla, Oscar R. Colamonici, Eleanor N. Fish, Albert Heim, Beata Majchrzak, Shahab Uddin, Leonidas C. Platanias, Isabella M. Grumbach
Publikováno v:
Journal of Interferon & Cytokine Research. 19:797-801
We determined whether selective activation of components of the Jak-Stat pathway by different type I interferons (IFN) occurs in human myocardial fibroblasts that exhibit much higher sensitivity to the antiviral effects of IFN-beta than of IFN-alpha.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2875705568accc29210309e4d1da5c
https://doi.org/10.1089/107999099313659
https://doi.org/10.1089/107999099313659