Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Oscar Okwudiri, Onyema"'
Autor:
Hung Cao Dinh, Ivan Bautmans, Ingo Beyer, Oscar Okwudiri Onyema, Keliane Liberman, Liza De Dobbeleer, Wim Renmans, Sam Vander Meeren, Kristin Jochmans, Andreas Delaere, Veerle Knoop, Rose Njemini
Publikováno v:
Immunity & Ageing, Vol 16, Iss 1, Pp 1-14 (2019)
Abstract Background Ageing is associated with a decline in immune function termed immunosenescence. This process is characterized amongst others by less naive T-cells and more senescent phenotypes, which have been implicated in the pathogenesis of ma
Externí odkaz:
https://doaj.org/article/b8fd050a32044832978fe94b378bfaa9
Autor:
Yizhan Guo, Thomas H. Barker, Anirban Banerjee, Qing Wang, Amir Manafi, Bayan Mahgoub, Oscar Okwudiri Onyema, Daniel Kreisel, Andrew E. Gelman, Zhongcheng Mei, Mark H. Stoler, Dongge Li, David S. Wilkes, Alexander S. Krupnick
Publikováno v:
American Journal of Transplantation. 19:2705-2718
Despite standardized postoperative care, some lung transplant patients suffer multiple episodes of acute and chronic rejection while others avoid graft problems for reasons that are poorly understood. Using an established model of C57BL/10 to C57BL/6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd069dc1648a01aa4b2c88cf6df2961f
https://doi.org/10.1111/ajt.15523
https://doi.org/10.1111/ajt.15523
Autor:
Mahmut Parlak, Yizhan Guo, Lei Shi, Lucy C. Sullivan, Qing Wang, Oscar Okwudiri Onyema, David L. Brautigan, Saeed Arefanian, Anirban Banerjee, Michael G. Brown, Timothy N. J. Bullock, Alexander S. Krupnick, Ulrike Lorenz, Edward B. Stelow, Kang Li
Publikováno v:
Proceedings of the National Academy of Sciences. 115:11808-11813
Natural killer (NK) cells play a critical role in controlling malignancies. Susceptibility or resistance to lung cancer, for example, specifically depends on NK cell function. Nevertheless, intrinsic factors that control NK cell-mediated clearance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d8b6c15def426ef549e6d7e89151a4
https://doi.org/10.1073/pnas.1804931115
https://doi.org/10.1073/pnas.1804931115
Autor:
Sam Vander Meeren, Ivan Bautmans, Keliane Liberman, Ingo Beyer, Kristin Jochmans, Liza De Dobbeleer, Oscar Okwudiri Onyema, Wim Renmans, Rose Njemini, Hung Cao Dinh, Andreas Delaere, Veerle Knoop
Publikováno v:
The Journals of Gerontology: Series A. 74:1870-1878
Aging is characterized by a progressive decline in immune function known as immunosenescence. Although the causes of immunosenescence are likely to be multifactorial, an age-associated accumulation of senescent T cells and decreased naive T-cell repe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5048675f8a030cc80b41af26f0d162
https://doi.org/10.1093/gerona/gly229
https://doi.org/10.1093/gerona/gly229
Autor:
Oscar Okwudiri Onyema, Daniel Kreisel, Elizabeth A. Jacobsen, Andrew E. Gelman, Yizhan Guo, Alexander S. Krupnick, Atsushi Hata
Publikováno v:
Am J Transplant
Eosinophils are rare granulocytes that belong to the innate arm of the immune system. This cell population is traditionally defined as a destructive and cytotoxic mediator in asthma and helminth infection. Limited data in transplantation have suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c788b663f2e9f8dac6c457117a10f45a
https://europepmc.org/articles/PMC7842192/
https://europepmc.org/articles/PMC7842192/
Autor:
Oscar Okwudiri Onyema, Kristin Jochmans, Sam Vander Meeren, Liza De Dobbeleer, Veerle Knoop, Andreas Delaere, Ivan Bautmans, Keliane Liberman, Ingo Beyer, Rose Njemini, Hung Cao Dinh, Wim Renmans
Publikováno v:
Immunity & Ageing : I & A
Immunity & Ageing, Vol 16, Iss 1, Pp 1-14 (2019)
Immunity & Ageing, Vol 16, Iss 1, Pp 1-14 (2019)
Background Ageing is associated with a decline in immune function termed immunosenescence. This process is characterized amongst others by less naive T-cells and more senescent phenotypes, which have been implicated in the pathogenesis of many age-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c8a39548827950285e8798450f87b28
http://europepmc.org/articles/PMC6657061
http://europepmc.org/articles/PMC6657061
Autor:
Bayan Mahgoub, Dongge Li, Andrew E. Gelman, Yizhan Guo, Anirban Banerjee, Adam G. Schrum, Alexander S. Krupnick, Melissa T. Zaidi, Daniel Kreisel, Mark H. Stoler, Amir Manafi, Oscar Okwudiri Onyema, Elizabeth A. Jacobsen, Qing Wang, Zhongcheng Mei
Publikováno v:
JCI Insight. 4
Despite the accepted notion that granulocytes play a universally destructive role in organ and tissue grafts, it has been recently described that eosinophils can facilitate immunosuppression-mediated acceptance of murine lung allografts. The mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8f588c63ab328b4764980a081cae03
https://doi.org/10.1172/jci.insight.128241
https://doi.org/10.1172/jci.insight.128241
Autor:
Daniel Kreisel, Oscar Okwudiri Onyema, Amir Manafi, Dongge Li, Andrew E. Gelman, Yizhan Guo, Alexander S. Krupnick, Zhongcheng Mei, Qing Wang
Publikováno v:
The Journal of Heart and Lung Transplantation. 38:S83-S84
Purpose Despite the growing experience in lung transplantation a significant number of patients rapidly succumb to chronic rejection in the form of bronchiolitis obliterans (OB). The reasons for such discrepancies are unknown but have been suspected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba822d2911f7f3269b671149e8ad4ab0
https://doi.org/10.1016/j.healun.2019.01.192
https://doi.org/10.1016/j.healun.2019.01.192
Autor:
Oscar Okwudiri Onyema, Wenjun Li, Daniel Kreisel, Yizhan Guo, Christopher D. Nazaroff, Mark H. Stoler, Qing Wang, Alexander S. Krupnick, Christine Lau, Elizabeth A. Jacobsen, Kang Li, James J. Lee, Andrew E. Gelman, Xingan Wang
Publikováno v:
JCI insight. 2(24)
Lungs allografts have worse long-term survival compared with other organ transplants. This is most likely due to their unique immunoregulation that may not respond to traditional immunosuppression. For example, local NO generation by inducible NOS (i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03174cc28f70338c87df79ef7d1b75b9
https://pubmed.ncbi.nlm.nih.gov/29263310
https://pubmed.ncbi.nlm.nih.gov/29263310
Autor:
Oscar Okwudiri Onyema, Yizhan Guo, Bayan Mahgoub, Amir Manafi, Stacey Criswell, Joanne Lannigan, Elizabeth A Jacobsen, Andrew E Gelman, Daniel Kreisel, Alexander S. Krupnick
Publikováno v:
The Journal of Immunology. 202:69.9-69.9
Eosinophils play a surprising role in downregulating lung graft-specific alloimmunity, even without immunosuppression. We demonstrate here, a mechanism used by eosinophils to downregulate alloimmune responses. To study the mechanism of eosinophil dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c3d91fa8398a253305e25ed07f5b209
https://doi.org/10.4049/jimmunol.202.supp.69.9
https://doi.org/10.4049/jimmunol.202.supp.69.9