The Allergy Archives: Pioneers and Milestones

Autor: Sheldon G. Cohen, Murray Dworetzky, Oscar L. Frick

Publikováno v: Journal of Allergy and Clinical Immunology. 111:205-210

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4489c27bf6c0f6301e6facaa26db4221
https://doi.org/10.1067/mai.2003.106

Thioredoxin-linked mitigation of allergic responses to wheat

Autor: B. C. Yee, Rosa Lozano, Oscar L. Frick, Karoly Kobrehel, M. Momma, Richard W. Ermel, Bob B. Buchanan, C. Adamidi

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 1997, 94, pp.5372-5377
Proceedings of the National Academy of Sciences of the United States of America (94), 5372-5377. (1997)

Thioredoxin, a ubiquitous 12-kDa regulatory disulfide protein, was found to reduce disulfide bonds of allergens (convert S-S to 2 SH) and thereby mitigate the allergenicity of commercial wheat preparations. Allergenic strength was determined by skin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f4bda4fd60518a4d9c098456eef189
https://doi.org/10.1073/pnas.94.10.5372

The level of expression of thioredoxin is linked to fundamental properties and applications of wheat seeds

Autor: Yongchun Li, Susumu Morigasaki, Hongbin Niu, Peggy G. Lemaux, H. K. Kim, Jun Yin, Jiangping Ren, Myeong-Je Cho, Joshua H. Wong, Bob B. Buchanan, Hongxiang Guo, Oscar L. Frick, Su-Mei Zhou, Yong-Bum Kim

Publikováno v: Molecular plant. 2(3)

Work with cereals (barley and wheat) and a legume (Medicago truncatula) has established thioredoxin h (Trx h) as a central regulatory protein of seeds. Trx h acts by reducing disulfide (S-S) groups of diverse seed proteins (storage proteins, enzymes,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e9dc5132f6d9a71e231461136e7afd
https://pubmed.ncbi.nlm.nih.gov/19825627

Neuropeptides, mast cells and allergy: novel mechanisms and therapeutic possibilities

Autor: S. P. Sreedharan, Daniel C. Adelman, Avi Hassner, P. P. J. Cheng, Edward J. Goetzl, Oscar L. Frick

Publikováno v: Clinical Experimental Allergy. 20:3-7

Diverse neuropeptides are released by neuroendocrine and immune cells at the sites of allergic and inflammatory reactions. The neuropeptides and other neuromediators affect functions of smooth muscle, microvasculature and secretory cells, and are pot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d911a3ab8680e8039454b3f4a044206
https://doi.org/10.1111/j.1365-2222.1990.tb02469.x

Allergen immunotherapy with heat-killed Listeria monocytogenes alleviates peanut and food-induced anaphylaxis in dogs

Autor: Oscar L. Frick, Suzanne S. Teuber, Susumu Morigasaki, Bob B. Buchanan, D. T. Umetsu

Publikováno v: Allergy. 60(2)

Background: Heat-killed Listeria monocytogenes (HKL) potently stimulates interferon (IFN)-γ production in CD4 T-lymphocytes, and when used as adjuvant for immunotherapy, reduces immunoglobulin (Ig)E production and reverses established allergen-induc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e469481ca5f10b8b3bb65d95a1e31bb0
https://pubmed.ncbi.nlm.nih.gov/15647048