Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Oscar Kuang Sheng Lee"'
Autor:
Xiaobo Zhu, Mingde Cao, Kejia Li, Yau-Tsz Chan, Hon-Fai Chan, Yi-Wah Mak, Hao Yao, Jing Sun, Michael Tim-Yun Ong, Kevin Ki-Wai Ho, Chien-Wei Lee, Oscar Kuang-Sheng Lee, Patrick Shu-Hang Yung, Yangzi Jiang
Publikováno v:
Bioactive Materials, Vol 39, Iss , Pp 255-272 (2024)
Osteoarthritis (OA) is a major clinical challenge, and effective disease-modifying drugs for OA are still lacking due to the complicated pathology and scattered treatment targets. Effective early treatments are urgently needed to prevent OA progressi
Externí odkaz:
https://doaj.org/article/65efe12f07f7452db3d7098879962681
Autor:
Wei-Ting Lin, Hao-Hsiang Wu, Chien-Wei Lee, Yu-Fan Chen, Lawrence Huang, Jennifer Hui-Chun Ho, Oscar Kuang-Sheng Lee
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102102- (2024)
Acute lung injury (ALI) is a life-threatening condition with limited treatment options. The pathogenesis of ALI involves macrophage-mediated disruption and subsequent repair of the alveolar barriers, which ultimately results in lung damage and regene
Externí odkaz:
https://doaj.org/article/b094449b64fc48d8b3e309fe915326b0
Autor:
Chao-Yang Chen, Shih-Hsien Yang, Ping-Ying Chang, Su-Feng Chen, Shin Nieh, Wen-Yen Huang, Yu-Chun Lin, Oscar Kuang-Sheng Lee
Publikováno v:
Cells, Vol 13, Iss 16, p 1334 (2024)
Colorectal cancer (CRC) is a leading cause of cancer mortality worldwide, and cancer-associated fibroblasts (CAFs) play a major role in the tumor microenvironment (TME), which facilitates the progression of CRC. It is critical to understand how CAFs
Externí odkaz:
https://doaj.org/article/6b4e4d34d99741279c61afb4750fff04
Autor:
Belle Yu-Hsuan Wang, Allen Wei-Ting Hsiao, Hoi Ting Shiu, Nicodemus Wong, Amanda Yu-Fan Wang, Chien-Wei Lee, Oscar Kuang-Sheng Lee, Wayne Yuk-Wai Lee
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Background High dosage of dexamethasone (Dex) is an effective treatment for multiple diseases; however, it is often associated with severe side effects including muscle atrophy, resulting in higher risk of falls and poorer life quality of pa
Externí odkaz:
https://doaj.org/article/0a2116ecbdfb4c19ba4b5b75edf479c0
Autor:
Belle Yu‐Hsuan Wang, Yi‐Fan Chen, Allen Wei‐Ting Hsiao, Wan‐Jing Chen, Chien‐Wei Lee, Oscar Kuang‐Sheng Lee
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 3, Pp 1349-1364 (2023)
Abstract Background The progressive deterioration of tissue–tissue crosstalk with aging causes a striking impairment of tissue homeostasis and functionality, particularly in the musculoskeletal system. Rejuvenation of the systemic and local milieu
Externí odkaz:
https://doaj.org/article/23783ed0d4b6483c995fcb927f8b1f17
Autor:
Kuan-Jung Chen, Wei Hsiung, Chien-Yuan Wang, Oscar Kuang-Sheng Lee, Kuo-Kuang Huang, Ye Huang, Jesse Chieh-Szu Yang
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0296300 (2024)
ObjectiveThis study aimed to compare the stability and mechanical properties of the double chevron-cut (DCC) and biplanar (BP) distal femoral osteotomy (DFO) techniques, along with analyzing their respective contact surface areas.MethodsBiomechanical
Externí odkaz:
https://doaj.org/article/03435efb02fd49cd973d52588b338f60
Autor:
Chun-Yu Lin, Jacky Chung-Hao Wu, Yen-Ming Kuan, Yi-Chun Liu, Pi-Yi Chang, Jun-Peng Chen, Henry Horng-Shing Lu, Oscar Kuang-Sheng Lee
Publikováno v:
Bioengineering, Vol 11, Iss 4, p 399 (2024)
Background and objective: Local advanced rectal cancer (LARC) poses significant treatment challenges due to its location and high recurrence rates. Accurate early detection is vital for treatment planning. With magnetic resonance imaging (MRI) being
Externí odkaz:
https://doaj.org/article/3c7c310689cb48daa55f2387d906c62e
Publikováno v:
Chinese Journal of Physiology, Vol 66, Iss 2, Pp 55-64 (2023)
Mesenchymal stem cells (MSCs) possess the capacity for self-renewal and multipotency. The traditional approach to manipulating MSC's fate choice predominantly relies on biochemical stimulation. Accumulating evidence also suggests the role of physical
Externí odkaz:
https://doaj.org/article/fe0b79756a6640b6a1079d4307ec1202
Autor:
Kuo-Hsuan Hung, Yu-Ching Kao, Yu-Hsuan Tang, Yi-Ting Chen, Chuen-Heng Wang, Yu-Chen Wang, Oscar Kuang-Sheng Lee
Publikováno v:
BMC Ophthalmology, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background To verify efficacy of automatic screening and classification of glaucoma with deep learning system. Methods A cross-sectional, retrospective study in a tertiary referral hospital. Patients with healthy optic disc, high-tension, or
Externí odkaz:
https://doaj.org/article/c7ce4bc65a0b404ebe5d671662811dfa
Autor:
Chien-Wei Lee, Yi-Fan Chen, Allen Wei-Ting Hsiao, Amanda Yu-Fan Wang, Oscar Yuan-Jie Shen, Belle Yu-Hsuan Wang, Lok Wai Cola Ho, Wei-Ting Lin, Chung Hang Jonathan Choi, Oscar Kuang-Sheng Lee
Publikováno v:
Journal of Advanced Research, Vol 39, Iss , Pp 73-88 (2022)
Introduction: The regenerative capacity of mesenchymal stromal cells or medicinal signaling cells (MSCs) is largely mediated by their secreted small extracellular vesicles (sEVs), and the therapeutic efficacy of sEVs can be enhanced by licensing appr
Externí odkaz:
https://doaj.org/article/ce36e7b18faa4f509488b9076466086f