Zobrazeno 1 - 10 of 468 pro vyhledávání: '"Oscar De Leon"'
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Akademický článek
Safety of Co-Crystal of Tramadol-Celecoxib (CTC) in Patients with Acute Moderate-to-Severe Pain: Pooled Analysis of Three Phase 3 Randomized Trials
Autor: Eugene R. Viscusi, Richard Langford, Adelaida Morte, Anna Vaqué, Jesús Cebrecos, Mariano Sust, José María Giménez-Arnau, Oscar de Leon-Casasola
Publikováno v: Pain and Therapy, Vol 13, Iss 6, Pp 1617-1631 (2024)
Abstract Introduction Multi-modal analgesia is desirable for the management of acute pain since it can provide effective pain relief at lower doses, thereby aiding tolerability. Co-crystal of tramadol-celecoxib (CTC) provides effective analgesia in m
Externí odkaz: https://doaj.org/article/915a54414edb4cf9857235723f72b67d
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2
Akademický článek
Efficacy of Co-Crystal of Tramadol-Celecoxib (CTC) in Patients with Acute Moderate-to-Severe Pain: A Pooled Analysis of Data from Two Phase 3 Randomized Clinical Trials
Autor: Richard Langford, Eugene R. Viscusi, Adelaida Morte, Jesús Cebrecos, Mariano Sust, José María Giménez-Arnau, Oscar de Leon-Casasola
Publikováno v: Drugs in R&D, Vol 24, Iss 2, Pp 239-252 (2024)
Abstract Background and Objectives New acute pain medications are needed that provide effective analgesia while minimizing side effects and opioid exposure. Clinical trials of co-crystal of tramadol-celecoxib (CTC) have demonstrated an improved benef
Externí odkaz: https://doaj.org/article/19b3c818f9a44197b7fa0da272900cc9
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3
Akademický článek
Global burden of respiratory infections associated with seasonal influenza in children under 5 years in 2018: a systematic review and modelling study
Autor: Xin Wang, MSc, You Li, PhD, Katherine L O'Brien, ProfMD, Shabir A Madhi, ProfPhD, Marc-Alain Widdowson, VetMB, Peter Byass, ProfPhD, Saad B Omer, ProfPhD, Qalab Abbas, MBBS, Asad Ali, MD, Alberta Amu, MD, Eduardo Azziz-Baumgartner, MD, Quique Bassat, ProfMD, W Abdullah Brooks, MD, Sandra S Chaves, MD, Alexandria Chung, BMedSci(H), Cheryl Cohen, MD, Marcela Echavarria, PhD, Rodrigo A Fasce, BSc, Angela Gentile, ProfMD, Aubree Gordon, PhD, Michelle Groome, PhD, Terho Heikkinen, ProfMD, Siddhivinayak Hirve, PhD, Jorge H Jara, MD, Mark A Katz, MD, Najwa Khuri-Bulos, ProfMD, Anand Krishnan, ProfMD, Oscar de Leon, BSc, Marilla G Lucero, MD, John P McCracken, ScD, Ainara Mira-Iglesias, MSc, Jennifer C Moïsi, PhD, Patrick K Munywoki, PhD, Millogo Ourohiré, MD, Fernando P Polack, ProfMD, Manveer Rahi, MBChB, Zeba A Rasmussen, MD, Barbara A Rath, ProfMD, Samir K Saha, ProfPhD, Eric AF Simões, ProfMD, Viviana Sotomayor, MPH, Somsak Thamthitiwat, MD, Florette K Treurnicht, PhD, Marylene Wamukoya, MPH, Lay-Myint Yoshida, ProfPhD, Heather J Zar, ProfPhD, Harry Campbell, ProfMD, Harish Nair, ProfPhD
Publikováno v: The Lancet Global Health, Vol 8, Iss 4, Pp e497-e510 (2020)
Summary: Background: Seasonal influenza virus is a common cause of acute lower respiratory infection (ALRI) in young children. In 2008, we estimated that 20 million influenza-virus-associated ALRI and 1 million influenza-virus-associated severe ALRI
Externí odkaz: https://doaj.org/article/409dc8b84c024523a735cf915d006f29
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4
Facial reconstruction in mucormycosis: A case report
Autor: Luis Nieto M.D., Oscar de Leon M.D., Nicolas Luna Acero M.D., Francico Rojas Badillo M.D., Valentina Arenas Arenas M.D.
INTRODUCTION: Mucormycosis is a rare opportunistic infectious pathology of angioinvasive fungal etiology produced by fungi of the order Mucorales characterized by a rapidly progressive invasion of the host vasculature by hyphae, resulting in ischemia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98cfe45d5d592c92ac49080880bdd166
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6
Celecoxib-tramadol co-crystal in patients with moderate-to-severe pain following bunionectomy with osteotomy: A phase 3, randomized, double-blind, factorial, active- and placebo-controlled trial
Autor: Eugene R. Viscusi, Oscar de Leon‐Casasola, Jesús Cebrecos, Adam Jacobs, Adelaida Morte, Esther Ortiz, Mariano Sust, Anna Vaqué, Ira Gottlieb, Stephen Daniels, Joseph S. Gimbel, Derek Muse, Peter Winkle, Michael E. Kuss, Sebastián Videla, Neus Gascón, Carlos Plata‐Salamán
Publikováno v: Pain practice : the official journal of World Institute of PainREFERENCES.
Celecoxib-tramadol co-crystal (CTC) is a first-in-class analgesic co-crystal of celecoxib and racemic tramadol with an improved pharmacologic profile, conferred by the co-crystal structure, compared with its active constituents administered alone/con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52c331d4866bad70763dd1cfb83ddb5
https://pubmed.ncbi.nlm.nih.gov/35686380
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9
Impact of perioperative pain management on cancer recurrence: an ASRA/ESRA special article
Autor: Vijay Gottumukkala, Ricardo Vallejo, Juan P. Cata, Alain Borgeat, Andres Missair, Donal J. Buggy, Gina Votta-Velis, Esther Benedetti de Marrero, Mark Johnson, D. I. Sessler, Marc A. Huntoon, Jose De Andres, Mohammed Tiouririne, Oscar De Leon Casasola
Publikováno v: Regional Anesthesia & Pain Medicine. 44:13-28
Cancer causes considerable suffering and 80% of advanced cancer patients experience moderate to severe pain. Surgical tumor excision remains a cornerstone of primary cancer treatment, but is also recognized as one of the greatest risk factors for met
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61960bf8fc5e48b13d656a4570cfabfa
https://doi.org/10.1136/rapm-2018-000001
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10
LPG stove and fuel intervention among pregnant women reduce fine particle air pollution exposures in three countries: Pilot results from the HAPIN trial
Autor: Usha Ramakrishnan, Shirin Jabbarzadeh, Pattie Lenzen, Erick Mollinedo, Rachel Meyers, Penelope P. Howards, Anaite Diaz-Artiga, Ajay Pillarisetti, Kyle Steenland, Krishnendu Mukhopadhyay, Jiawen Liao, Kalpana Balakrishnan, Eduardo Canuz, Jean de Dieu Ntivuguruzwa, Fiona Majorin, Sheela S. Sinharoy, Ashlinn Quinn, Thomas Clasen, Miles A. Kirby, Eric D. McCollum, Jane Mbabazi, Ghislaine Rosa, Marilu Chiang, Bonnie N. Young, John P. McCracken, Viviane Valdes, Bernard Mutariyani, Florien Ndagijimana, Amy Lovvorn, Alejandra Bussalleu, Gloriose Bankundiye, Maggie L. Clark, Luke P. Naeher, Dana B. Barr, Suzanne M. Simkovich, Elisa Puzzolo, Steven A. Harvey, Gurusamy Thangavel, Naveen Puttaswamy, Jeremy A. Sarnat, Kendra N. Williams, Lisa M. Thompson, Wenlu Ye, Damien Swearing, Kirk R. Smith, Sankar Sambandam, Sarada S. Garg, Katherine A. Kearns, Lawrence H. Moulton, Rengaraj Ramasami, Yunyun Chen, Vigneswari Aravindalochanan, Marvin Johnson, Lisa de las Fuentes, Alexander Ramirez, Ian Hennessee, William Checkley, Ashley Toenjes, Shakir Hossen, Ricardo Piedrahita, P. Barry Ryan, Karthikeyan Rajamani, Joshua P. Rosenthal, Lisa Elon, Lindsay M. Jaacks, Ephrem Dusabimana, Jennifer L. Peel, Durairaj Natesan, Mayari Hengstermann, Lance A. Waller, Rachel Craik, Oscar de Leon, Victor G. Davila-Roman, Azhar Nizam, Aris T. Papageorghiou, Alexie Mukeshimana, Juan Gabriel Espinoza, Sudhakar Saidam, Adly Castañaza, Sarah Hamid, Phabiola Herrera, Stella Hartinger
Publikováno v: Environmental Pollution (Barking, Essex : 1987)
The Household Air Pollution Intervention Network trial is a multi-country study on the effects of a liquefied petroleum gas (LPG) stove and fuel distribution intervention on women's and children's health. There is limited data on exposure reductions
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7cc12c7cc0d8f5d07fdcaf148ba718
https://pubmed.ncbi.nlm.nih.gov/34740288
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