Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Oscar C. Salgado"'
Autor:
Zengdi Zhang, Oscar C. Salgado, Bing Liu, Zahra Moazzami, Kristin A. Hogquist, Michael A. Farrar, Hai-Bin Ruan
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The immunosuppressive regulatory T (Treg) cells exert emerging effects on adipose tissue homeostasis and systemic metabolism. However, the metabolic regulation and effector mechanisms of Treg cells in coping with obesogenic insults are not fully unde
Externí odkaz:
https://doaj.org/article/5a8d1a5f31b14dce8daa1bc355c690e2
Autor:
Bing Liu, Oscar C. Salgado, Sangya Singh, Keli L. Hippen, Jason C. Maynard, Alma L. Burlingame, Lauren E. Ball, Bruce R. Blazar, Michael A. Farrar, Kristin A. Hogquist, Hai-Bin Ruan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The transcription factor Foxp3 and Stat5 modulate lineage stability and function of regulatory T (Treg) cells to promote immune homeostasis. Here the authors show that O-GlcNAcylation of Foxp3 and Stat5, mediated by O-GlcNAc transferase (OGT), is ess
Externí odkaz:
https://doaj.org/article/753e12c8c75848d7bf15336570926002
Autor:
Frances V. Sjaastad, Matthew A. Huggins, Erin D. Lucas, Cara Skon-Hegg, Whitney Swanson, Matthew D. Martin, Oscar C. Salgado, Julie Xu, Mark Pierson, Thamotharampillai Dileepan, Tamara A. Kucaba, Sara E. Hamilton, Thomas S. Griffith
Publikováno v:
The Journal of Immunology. 209:2149-2159
Successful vaccination strategies offer the potential for lifelong immunity against infectious diseases and cancer. There has been increased attention regarding the limited translation of some preclinical findings generated using specific pathogen-fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872f7a37664b90156082e0ec32861d51
https://doi.org/10.4049/jimmunol.2200324
https://doi.org/10.4049/jimmunol.2200324
Autor:
Elise R. Breed, Matouš Vobořil, Katherine M. Ashby, Ryan J. Martinez, Lily Qian, Haiguang Wang, Oscar C. Salgado, Christine H. O’Connor, Kristin A. Hogquist
Publikováno v:
Nature Immunology. 23:1042-1051
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a7b9d2dfb3ef3caa1f7be3027f69771
https://doi.org/10.1038/s41590-022-01218-x
https://doi.org/10.1038/s41590-022-01218-x
Autor:
Ryan J. Martinez, Elise R. Breed, Yosan Worota, Katherine M. Ashby, Matouš Vobořil, Tailor Mathes, Oscar C. Salgado, Christine H. O’Connor, Sergei V. Kotenko, Kristin A. Hogquist
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The activation of thymic B cells is critical for their licensing as antigen presenting cells and resulting ability to mediate T cell central tolerance. The processes leading to licensing are still not fully understood. By comparing thymic B cells to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::530cb14683162587eb4f389d5cf42d48
https://doi.org/10.1073/pnas.2220120120
https://doi.org/10.1073/pnas.2220120120
Autor:
Ming Zhao, Kaiqun Ren, Xiwen Xiong, Yue Xin, Yujie Zou, Jason C. Maynard, Angela Kim, Alexander P. Battist, Navya Koneripalli, Yusu Wang, Qianyue Chen, Ruyue Xin, Chenyan Yang, Rong Huang, Jiahui Yu, Zan Huang, Zengdi Zhang, Haiguang Wang, Daoyuan Wang, Yihui Xiao, Oscar C. Salgado, Nicholas N. Jarjour, Kristin A. Hogquist, Xavier S. Revelo, Alma L. Burlingame, Xiang Gao, Jakob von Moltke, Zhaoyu Lin, Hai-Bin Ruan
Publikováno v:
Immunity
The epithelium is an integral component of mucosal barrier and host immunity. Following helminth infection, the intestinal epithelial cells secrete "alarmin" cytokines, such as interleukin-25 (IL-25) and IL-33, to initiate the type 2 immune responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a55872d8119a1575f1fd3cc2f388c52
https://pubmed.ncbi.nlm.nih.gov/35830826
https://pubmed.ncbi.nlm.nih.gov/35830826
Publikováno v:
The Journal of Immunology. 208:107.05-107.05
Autoimmune diseases are triggered by the loss of immunological tolerance to self-antigens. Although previous work has characterized mechanisms driving immune tolerance to tissue restricted self-antigens, less is understood about how tolerance is esta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e94bad6a0d5a714396d26a053e2d362f
https://doi.org/10.4049/jimmunol.208.supp.107.05
https://doi.org/10.4049/jimmunol.208.supp.107.05
Autor:
Roland Ruscher, Kristin A. Hogquist, Oscar C. Salgado, Sara H. Osum, S. Thera Lee, Elise R. Breed
Publikováno v:
The Journal of Experimental Medicine
Molecular time-stamp experiments reveal that CD8αα IELs become established in the intestine largely in the first weeks of life. The TCR usage of the IELs that seed the gut initially compared with later in life differs, suggesting functional heterog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5014a5650e8091121bd1392420dca4fd
https://doi.org/10.1084/jem.20192336
https://doi.org/10.1084/jem.20192336
Autor:
Oscar C. Salgado Barrero, Hai Bin Ruan
Publikováno v:
Diabetes. 69
Adipose tissue-resident regulatory T (Treg) cells have been proposed to exert metabolic roles in controlling inflammation, insulin sensitivity and thermogenesis. However, it is still largely unclear how Treg cells integrate immunological and metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb47458a6a3fccb3d66e89ef30b40467
https://doi.org/10.2337/db20-292-or
https://doi.org/10.2337/db20-292-or
Autor:
Oscar C. Salgado, Kristin A. Hogquist
Publikováno v:
Nature Immunology. 20:952-954
Characterization of the self antigens that neonatal regulatory T cells recognize reveals dramatic effects of age and inflammation on the fate of T cells developing in the thymus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88a04ad7058e34fca1517e5b01c757a1
https://doi.org/10.1038/s41590-019-0440-z
https://doi.org/10.1038/s41590-019-0440-z