Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Oscar Bartulos"'
Autor:
Matthijs Snelders, Iris H. Koedijk, Julia Schirmer, Otto Mulleners, Juancito van Leeuwen, Nathalie P. de Wagenaar, Oscar Bartulos, Pieter Voskamp, Stefan Braam, Zeno Guttenberg, A.H. Jan Danser, Danielle Majoor-Krakauer, Erik Meijering, Ingrid van der Pluijm, Jeroen Essers
Publikováno v:
Biomaterials and Biosystems, Vol 8, Iss , Pp 100068- (2022)
Current in vivo disease models and analysis methods for cardiac drug development have been insufficient in providing accurate and reliable predictions of drug efficacy and safety. Here, we propose a custom optical flow-based analysis method to quanti
Externí odkaz:
https://doaj.org/article/3c0f49b15c77485f83a3373cfb3b7a85
Autor:
Biraja C. Dash, Karen Levi, Jonas Schwan, Jiesi Luo, Oscar Bartulos, Hongwei Wu, Caihong Qiu, Ting Yi, Yongming Ren, Stuart Campbell, Marsha W. Rolle, Yibing Qyang
Publikováno v:
Stem Cell Reports, Vol 7, Iss 1, Pp 19-28 (2016)
There is an urgent need for an efficient approach to obtain a large-scale and renewable source of functional human vascular smooth muscle cells (VSMCs) to establish robust, patient-specific tissue model systems for studying the pathogenesis of vascul
Externí odkaz:
https://doaj.org/article/78de9c9033464861b65086094fd511cd
Autor:
Esra Cagavi, Oscar Bartulos, Carol Y Suh, Baonan Sun, Zhichao Yue, Zhengxin Jiang, Lixia Yue, Yibing Qyang
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e110752 (2014)
As heart failure due to myocardial infarction remains a leading cause of morbidity worldwide, cell-based cardiac regenerative therapy using cardiac progenitor cells (CPCs) could provide a potential treatment for the repair of injured myocardium. As a
Externí odkaz:
https://doaj.org/article/59ee67bfe7a946879405f0645de74233
Autor:
Thomas Hutschalik, Ozan Özgül, Marilù Casini, Brigitta Szabó, Rémi Peyronnet, Óscar Bártulos, Mariana Argenziano, Ulrich Schotten, Elena Matsa
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Background Atrial fibrillation has an estimated prevalence of 1.5–2%, making it the most common cardiac arrhythmia. The processes that cause and sustain the disease are still not completely understood. An association between atrial fibrill
Externí odkaz:
https://doaj.org/article/62230f7377c342b9b213ccfb407b8704
Autor:
Jiesi Luo, Stuart G. Campbell, Yibing Qyang, David H. Sachs, Alan Dardik, Marsha W. Rolle, Liqiong Gui, Peining Li, George Tellides, Xiaoqiang Cong, Xia Li, Darrell N. Kotton, Laura E. Niklason, Lingfeng Qin, Jordan S. Pober, Matthew W. Ellis, Jonas Schwan, Yongming Ren, Mehmet H. Kural, Guangxin Li, Robert J. Hawley, Oscar Bartulos
Publikováno v:
Biomaterials. 147:116-132
Development of autologous tissue-engineered vascular constructs using vascular smooth muscle cells (VSMCs) derived from human induced pluripotent stem cells (iPSCs) holds great potential in treating patients with vascular disease. However, preclinica
Autor:
Jonas Schwan, Yibing Qyang, Andrea T. Kwaczala, Yongming Ren, Lorenzo R. Sewanan, Oscar Bartulos, Aaron H. Morris, Stuart G. Campbell, Daniel Jacoby, Thomas J. Ryan
Publikováno v:
Scientific Reports
We have developed an engineered heart tissue (EHT) system that uses laser-cut sheets of decellularized myocardium as scaffolds. This material enables formation of thin muscle strips whose biomechanical characteristics are easily measured and manipula
Autor:
Alda Bregasi, Yibing Qyang, Nicole Mikush, Diane S. Krause, Lin Wang, Carol Y. Suh, Yan Huang, Jordan S. Pober, Oscar Bartulos, Zhen W. Zhuang, William G. Chang, Lawrence H. Young
Publikováno v:
JCI insight. 1(10)
Cardiovascular progenitor cells (CPCs) expressing the ISL1-LIM-homeodomain transcription factor contribute developmentally to cardiomyocytes in all 4 chambers of the heart. Here, we show that ISL1-CPCs can be applied to myocardial regeneration follow
Autor:
Catalina Hernández-Sánchez, Carmen Lopez-Sanchez, Flora de Pablo, A.I. Valenciano, Oscar Bartulos, Enrique Martínez-Campos, Virginio Garcia-Martinez, Carlos M. Gañan
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scopus-Elsevier
instname
Scopus-Elsevier
47 p.-5 fig.-6 supl.tab.-5 supl.fig.
AimsTyrosine hydroxylase (TH) is the first and rate-limiting enzyme in catecholamine biosynthesis. Whereas the neuroendocrine roles of cathecolamines postnatally are well known, the presence and function of T
AimsTyrosine hydroxylase (TH) is the first and rate-limiting enzyme in catecholamine biosynthesis. Whereas the neuroendocrine roles of cathecolamines postnatally are well known, the presence and function of T
Autor:
Oscar Bartulos
Publikováno v:
Journal of Heart Health. 1
Mortality rate in patients that suffer heart failure is approximately 50 per cent in a 5-year follow up, exceeding the mortality detected in patients with cancer. Angiotensin Converting Enzyme (ACE) inhibitors and beta-blockers are effective to treat
Publikováno v:
Journal of cardiovascular pharmacology and therapeutics. 19(4)
Cardiovascular diseases remain the leading causes of morbidity and mortality in the developed world. Cellular based cardiac regenerative therapy serves as a potential approach to treating cardiovascular diseases. Although various cellular types have