Non-synonymous variation and protein structure of candidate genes associated with selection in farm and wild populations of turbot (Scophthalmus maximus)

Autor: Øivind Andersen, Juan Andrés Rubiolo, Davide Pirolli, Oscar Aramburu, Marina Pampín, Benedetta Righino, Diego Robledo, Carmen Bouza, Maria Cristina De Rosa, Paulino Martínez

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)

Abstract Non-synonymous variation (NSV) of protein coding genes represents raw material for selection to improve adaptation to the diverse environmental scenarios in wild and livestock populations. Many aquatic species face variations in temperature,

Externí odkaz: https://doaj.org/article/f6b48c165c714a34be0472370f0bc92c

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Utilidad pronóstica de las cifras ambulatorias de presión arterial en pacientes de edad avanzada con insuficiencia cardíaca. Resultados del estudio DICUMAP

Autor: Óscar Aramburu Bodas, Manuel Méndez Bailón, Jesús Díez-Manglano, Fernando Salgado Ordóñez, M. Montero Pérez-Barquero, Miguel Camafort, José Manuel Varela Aguilar, Jorge Francisco, Luis Manzano Espinosa, Jordi Grau Amorós, Oscar Aramburu, Manuel Montero Pérez-Barquero, los investigadores Dicumap, J.C. Arévalo-Lorido, Pardeep S. Jhund, Javier Sobrino Martínez, José Luis Arias Jiménez, Nuria Ribas Pizá, Miguel Camafort Babkowski, Gerard Torres Cortada, Gonzalo Martínez de las Cuevas, J. Vila, Jorge Gómez Cerezo, Luis Manzano, Javier Sobrino-Martinez, Francesc Formiga, A. Castro-Salomó, Jose Carlos Arévalo Lorido, Jesús Díez Manglano

Publikováno v: Revista Clínica Española. 221:433-440

Resumen Introduccion La monitorizacion ambulatoria de la presion arterial (MAPA) ha demostrado la utilidad en la evaluacion pronostica de los pacientes hipertensos con insuficiencia cardiaca (IC) con o sin otras enfermedades cardiovasculares. El obje

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d75852e2c39adf68b6739b91f4a2bf3
https://doi.org/10.1016/j.rce.2020.11.010

Mechanism of Vascular Toxicity in Rats Subjected to Treatment with a Tyrosine Kinase Inhibitor

Autor: Oscar Aramburu, Álvaro Santana-Garrido, Claudia Reyes-Goya, Estefanía Soto-Astacio, Sonia Zambrano, Alfonso Mate, Carmen Vázquez

Publikováno v: Toxics
Volume 8
Issue 3
Digital.CSIC. Repositorio Institucional del CSIC
instname
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
idUS. Depósito de Investigación de la Universidad de Sevilla
Toxics, Vol 8, Iss 49, p 49 (2020)

Sunitinib (Su) is a tyrosine kinase inhibitor with antiangiogenic and antineoplastic effects that is recommended therapy for renal cell carcinoma, gastrointestinal stromal tumors, and pancreatic neuroendocrine tumors. Arterial hypertension is one of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c799bb1c16ac31d2c4c6e9403cea2459

Inflammatory and fibrotic processes are involved in the cardiotoxic effect of sunitinib: Protective role of l -carnitine

Autor: Sonia Zambrano, Carmen Vázquez, José L. Miguel-Carrasco, José L. Arias, Oscar Aramburu, Alfonso Mate, Miguel Arévalo, Antonio J. Blanca, María V. Ruiz-Armenta

Publikováno v: Toxicology Letters. 241:9-18

Sunitinib (Su) is currently approved for treatment of several malignances. However, along with the benefits of disease stabilization, cardiovascular toxicities have also been increasingly recognized. The aim of this study was to analyze which mechani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac39806618d2daa05977f67ec442fb1
https://doi.org/10.1016/j.toxlet.2015.11.007