Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Oscar A. Hernandez Murillo"'
Autor:
Amber Tariq, JiaBei Lin, Meredith E. Jackrel, Christina D. Hesketh, Peter J. Carman, Korrie L. Mack, Rachel Weitzman, Craig Gambogi, Oscar A. Hernandez Murillo, Elizabeth A. Sweeny, Esin Gurpinar, Adam L. Yokom, Stephanie N. Gates, Keolamau Yee, Saurabh Sudesh, Jacob Stillman, Alexandra N. Rizo, Daniel R. Southworth, James Shorter
Publikováno v:
Cell Reports, Vol 28, Iss 8, Pp 2080-2095.e6 (2019)
Summary: Hsp104 is an AAA+ protein disaggregase, which can be potentiated via diverse mutations in its autoregulatory middle domain (MD) to mitigate toxic misfolding of TDP-43, FUS, and α-synuclein implicated in fatal neurodegenerative disorders. Pr
Externí odkaz:
https://doaj.org/article/bf589229a4c8478bb067db7496f89daf
