Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Oscar, Pan"'
Autor:
Derek E. Piper, William G. Romanow, Ruwanthi N. Gunawardane, Preston Fordstrom, Stephanie Masterman, Oscar Pan, Stephen T. Thibault, Richard Zhang, David Meininger, Margrit Schwarz, Zhulun Wang, Chadwick King, Mingyue Zhou, NigelP.C. Walker
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 9, Pp 1711-1719 (2015)
LCAT is intimately involved in HDL maturation and is a key component of the reverse cholesterol transport (RCT) pathway which removes excess cholesterol molecules from the peripheral tissues to the liver for excretion. Patients with loss-of-function
Externí odkaz:
https://doaj.org/article/b3706d7d8e0b442f9e08dfa98b04c870
Autor:
Zhulun Wang, David Park Meininger, Oscar Pan, Ruwanthi N. Gunawardane, Chadwick T. King, Richard Zhang, Mingyue Zhou, Stephen T. Thibault, Derek E. Piper, William G. Romanow, Nigel Walker, Preston Fordstrom, Margrit Schwarz, Stephanie Masterman
Publikováno v:
Journal of Lipid Research. 56:1711-1719
LCAT is intimately involved in HDL maturation and is a key component of the reverse cholesterol transport (RCT) pathway which removes excess cholesterol molecules from the peripheral tissues to the liver for excretion. Patients with loss-of-function
Autor:
Dong, Liu, Mandy, Tseng, Linda F, Epstein, Lydia, Green, Brian, Chan, Brian, Soriano, Desiree, Lim, Oscar, Pan, Christopher M, Murawsky, Chadwick T, King, Bryan D, Moyer
Publikováno v:
F1000Research
Identification of small and large molecule pain therapeutics that target the genetically validated voltage-gated sodium channel Na V1.7 is a challenging endeavor under vigorous pursuit. The monoclonal antibody SVmab1 was recently published to bind th
Autor:
Vibha Jawa, Karen Richmond, Jette Wypych, Martha M. Hokom, Theresa J. Goletz, Marisa K. Joubert, Jilin Sun, Lei Zhou, Bruce A. Kerwin, Oscar Pan, Catherine M. Eakin, Linda O. Narhi, Taruna Arora, Arunan Kaliyaperumal, Vivian Bi
Publikováno v:
Journal of Pharmaceutical Sciences. 102:3545-3555
We describe a novel human immunoglobulin G2 (IgG2)-tolerant and immune-competent heterozygous mouse model (Xeno-het) developed by crossbreeding a human Ig-tolerized XenoMouse® with a C57BL/6J wild-type mouse. The Xeno-het mouse expresses both mouse
Autor:
Brian Soriano, Desiree Lim, Chadwick T. King, Brian Mingtung Chan, Mandy Tseng, Dong Liu, Christopher Murawsky, Linda F. Epstein, Oscar Pan, Bryan D. Moyer, Lydia Green
Publikováno v:
F1000Research. 5:2764
Identification of small and large molecule pain therapeutics that target the genetically validated voltage-gated sodium channel NaV1.7 is a challenging endeavor under vigorous pursuit. The monoclonal antibody SVmab1 was recently published to bind the
Autor:
Higbee Jared Martin, Bei Shan, Margrit Schwarz, Wen-Chen Yeh, William G. Romanow, Qiong Cao, Mei Lu, Joyce Chi Yee Chan, Richard Zhang, Yongmei Di, Ping Cao, Maurice Emery, Evelyn Yang, Stephen T. Thibault, Lei Zhou, Susan Shetterly, Gayle Kwon, Timothy W. Yu, Dongming Liu, Wenyan D. Shen, Kirk Henne, Oscar Pan, Mei-Mei Tsai, Heather Salomonis, Bryna Fuchslocher, Ziva Arimura, Nigel Walker, Qiang Liu, Mark Daris, Derek E. Piper, Kijeong Lee, Simon Mark Jackson, Wei Wang, Chadwick T. King, Jie Tang, Xiao-Ping Yang, Jackie Sheng, Yan Wang, Marc W. Retter, Zhen Xia
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(24)
Proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates serum LDL cholesterol (LDL-C) by interacting with the LDL receptor (LDLR) and is an attractive therapeutic target for LDL-C lowering. We have generated a neutralizing anti-PCSK9 antibody
Publikováno v:
Cancer Research. 71:558-558
Modification of heparan sulfate proteoglycans (HSPG) in the tumour microenvironment can have a significant influence on tumour cell behavior, tumour growth and metastasis. HSPG play an important role in shaping the integrity of the extracellular matr