Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch

Autor: Abe, Y., Fujiwara, Y., Takahashi, H., Matsumura, Y., Sawada, T., Jiang, S., Nakaki, R., Uchida, A., Nagao, N., Naito, M., Kajimura, S., Kimura, Hiroshi, Osborne, T. F., Aburatani, H., Kodama, T., Inagaki, T., Sakai, J.

Publikováno v: Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)

In acute cold stress in mammals, JMJD1A, a histone H3 lysine 9 (H3K9) demethylase, upregulates thermogenic gene expressions through β-adrenergic signaling in brown adipose tissue (BAT). Aside BAT-driven thermogenesis, mammals have another mechanism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab4a8e4d4578802fb11578096f8f306
http://europepmc.org/articles/PMC5908789

Genome-wide analysis of FoxO1 binding in hepatic chromatin: Potential involvement of FoxO1 in linking retinoid signaling to hepatic gluconeogenesis

Autor: Shin, D.-J., Joshi, P., Hong, S.-H., Mosure, K., Shin, D.-G., Osborne, T. F

Publikováno v: Shin, D.-J.; Joshi, P.; Hong, S.-H.; Mosure, K.; Shin, D.-G.; & Osborne, T. F. (2012). Genome-wide analysis of FoxO1 binding in hepatic chromatin: Potential involvement of FoxO1 in linking retinoid signaling to hepatic gluconeogenesis. Nucleic Acids Research, 40(22), 11499-11509. doi: 10.1093/nar/gks932. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2zd997k4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::70bd33181938170e0a2e67f43fc437d3
http://www.escholarship.org/uc/item/2zd997k4

Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase.

Autor: Magaña, M M, Koo, S H, Towle, H C, Osborne, T F

Publikováno v: Journal of Biological Chemistry; February 2000, Vol. 275 Issue: 7 p4726-33, 8p

Co-stimulation of promoter for low density lipoprotein receptor gene by sterol regulatory element-binding protein and Sp1 is specifically disrupted by the yin yang 1 protein.

Autor: Bennett, M K, Ngo, T T, Athanikar, J N, Rosenfeld, J M, Osborne, T F

Publikováno v: Journal of Biological Chemistry; May 1999, Vol. 274 Issue: 19 p13025-32, 8p

Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

Autor: Gil, G, Smith, J R, Goldstein, J L, Slaughter, C A, Orth, K, Brown, M S, Osborne, T F

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; December 1988, Vol. 85 Issue: 23 p8963-8967, 5p