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pro vyhledávání: '"Osborne, James M."'
Increasingly, experimentalists and modellers alike have come to recognise the important role of spatial structure in infection dynamics. Almost invariably, spatial computational models of viral infections -- as with in vitro experimental systems -- r
Externí odkaz:
http://arxiv.org/abs/2408.07618
The maintenance of tissue and organ structures during dynamic homeostasis is often not well understood. In order for a system to be stable, cell renewal, cell migration and cell death must be finely balanced. Moreover, a tissue's shape must remain re
Externí odkaz:
http://arxiv.org/abs/2205.04592
Autor:
Osborne, James M.
Publikováno v:
In Journal of Theoretical Biology 7 November 2024 594
In this paper, we present and validate a simple adaptive surface remeshing technique to transfer history dependent variables from an old distorting mesh to a new mesh during finite element simulations of elastic surface deformation. This technique al
Externí odkaz:
http://arxiv.org/abs/2011.06756
Multicellular tissues are the building blocks of many biological systems and organs. These tissues are not static, but dynamically change over time. Even if the overall structure remains the same there is a turnover of cells within the tissue. This d
Externí odkaz:
http://arxiv.org/abs/2006.12909
Publikováno v:
In Journal of Theoretical Biology 21 September 2023 573
Akademický článek
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Publikováno v:
In Journal of Computational and Applied Mathematics 15 May 2022 405
Autor:
Kay, Sophie K., Harrington, Heather A., Shepherd, Sarah, Brennan, Keith, Dale, Trevor, Osborne, James M., Gavaghan, David J., Byrne, Helen M.
The Notch pathway plays a vital role in determining whether cells in the intestinal epithelium adopt a secretory or an absorptive phenotype. Cell fate specification is coordinated via Notch's interaction with the canonical Wnt pathway. Here, we propo
Externí odkaz:
http://arxiv.org/abs/1608.06146
Academic software development practices often differ from those of commercial development settings, yet only limited research has been conducted on assessing software development practises in academia. Here we present a case study of software develop
Externí odkaz:
http://arxiv.org/abs/1506.05272