Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Osato Ogbeifun"'
Autor:
Swapnalee Sarmah, Pooja Muralidharan, Courtney L. Curtis, Jeanette N. McClintick, Bryce B. Buente, David J. Holdgrafer, Osato Ogbeifun, Opeyemi C. Olorungbounmi, Liliana Patino, Ryan Lucas, Sonya Gilbert, Evan S. Groninger, Julia Arciero, Howard J. Edenberg, James A. Marrs
Publikováno v:
Biology Open, Vol 2, Iss 10, Pp 1013-1021 (2013)
Summary Fetal alcohol spectrum disorder (FASD) occurs when pregnant mothers consume alcohol, causing embryonic ethanol exposure and characteristic birth defects that include craniofacial, neural and cardiac defects. Gastrulation is a particularly sen
Externí odkaz:
https://doaj.org/article/027fb73922a846ae8da67340c6638256
Autor:
Wambui S Wandu, Cuiyan Tan, Osato Ogbeifun, Barbara P Vistica, Guangpu Shi, Samuel J H Hinshaw, Chengsong Xie, Xi Chen, Dennis M Klinman, Huaibin Cai, Igal Gery
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128906 (2015)
Mutations in LRRK2 are related to certain forms of Parkinson's disease and, possibly, to the pathogenesis of Crohn's disease. In both these diseases inflammatory processes participate in the pathogenic process. LRRK2 is expressed in lymphoid cells an
Externí odkaz:
https://doaj.org/article/d5759c03978d4c24a5912486766dcee2
Autor:
Osato Ogbeifun, Samuel J. H. Hinshaw, Lindsey F. Nugent, Ignacio R. Rodriguez, Igal Gery, Siqi Chen, Wambui S. Wandu, Arvydas Maminishkis, Guangpu Shi
Publikováno v:
Investigative Ophthalmology & Visual Science. 56:1658-1664
PURPOSE The inflammatory process plays a major role in the pathogenesis of AMD, and recent data indicate the involvement of inflammasomes. Inflammasomes are intracellular structures that trigger inflammation by producing mature interleukin-(IL)-1β a
Autor:
Igal Gery, Guangpu Shi, Yichao Li, Cancan Lyu, Osato Ogbeifun, Haohua Qian, Wambui S. Wandu, Samuel J. H. Hinshaw
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Digoxin, a major medication for heart disease, was recently reported to have immunosuppressive capacity. Here, we determined the immunosuppressive capacity of digoxin on the development of experimental autoimmune uveitis (EAU) and on related
Autor:
Xi Chen, Huaibin Cai, Osato Ogbeifun, Cuiyan Tan, Guangpu Shi, Barbara P. Vistica, Chengsong Xie, Wambui S. Wandu, Dennis M. Klinman, Samuel J. H. Hinshaw, Igal Gery
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128906 (2015)
PLoS ONE
PLoS ONE
Background Mutations in LRRK2 are related to certain forms of Parkinson’s disease and, possibly, to the pathogenesis of Crohn’s disease. In both these diseases inflammatory processes participate in the pathogenic process. LRRK2 is expressed in ly
Autor:
Samuel J. H. Hinshaw, Guangpu Shi, Barbara P. Vistica, Lindsey F. Nugent, Osato Ogbeifun, Igal Gery
Publikováno v:
Investigative ophthalmologyvisual science. 54(12)
Purpose Ligands for aryl hydrocarbon receptor (AHR), such as dioxins, are highly toxic. One such ligand, TCDD, was found to exert potent immunosuppressive capacities in mice developing pathogenic autoimmune processes, including EAU, but its toxicity